A report on the diagnosis of intermediate hyperglycemia in Korea: A pooled analysis of four community-based cohort studies

Oh, Jee Young; Lim, Soo; Kim, Dae Jung; Kim, Nan Hee; Kim, Dong Jun; Moon, Sung Dae; Jang, Hak Chul; Cho, Young Min; Song, Ki Ho; Ahn, Chul Woo; Sung, Yeon Ah; Park, Joong Yeol; Shin, Chol; Lee, Hong Kyu; Park, Kyong Soo

doi:10.1016/j.diabres.2008.01.022

Cited by 21 publications

(24 citation statements)

References 29 publications

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“…We classified FPG levels into the following five groups: normal fasting glucose (NFG) 1 (<90 mg/dL), NFG 2 (90–99 mg/dL), IFG 1 (100–110 mg/dL), IFG 2 (111–125 mg/dL) and diabetes, defined as either FPG ≥ 126 mg/dL, treatment with anti-diabetes drugs, or a history of diabetes diagnosed by a physician. 23 Logistic regression analysis was used to evaluate the odds ratios of the presence of diabetes or IFG for periodontitis and severe periodontitis according to age group using the above-mentioned variables as covariates. All of the tests were 2-sided, and P values <0.05 indicate statistical significance.…”

Section: Methodsmentioning

confidence: 99%

The Prevalence and Associated Factors of Periodontitis According to Fasting Plasma Glucose in the Korean Adults

2016

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Although the relationship between diabetes and periodontitis is well established, the association between periodontitis and prediabetes has been investigated less extensively. Furthermore, there has been little research on the prevalence of periodontitis among individuals with prediabetes and diabetes as well as in the overall population using nationally representative data.Among 12,406 adults (≥19 years’ old) who participated in the 2012–2013 Korea National Health and Nutrition Examination Survey, a total of 9977 subjects completed oral and laboratory examinations and were included in this analysis. Periodontitis was defined as a community periodontal index score of ≥3 according to the World Health Organization criteria. The fasting plasma glucose level was categorized into the following 5 groups: normal fasting glucose (NFG) 1 (<90 mg/dL), NFG 2 (90–99 mg/dL), impaired fasting glucose (IFG) 1 (100–110 mg/dL), IFG 2 (111–125 mg/dL), and diabetes (≥126 mg/dL).Overall, the weighted prevalence of periodontitis among the Korean adult population was 24.8% (23.3–26.4%) (weight n = 8,455,952/34,086,014). The unadjusted weighted prevalences of periodontitis were 16.7%, 22.8%, 29.6%, 40.7%, and 46.7% in the NFG 1, NFG 2, IFG 1, IFG 2, and diabetes groups, respectively (P < 0.001). After adjusting for age, sex, smoking history, heavy alcohol drinking, college graduation, household income, waist circumference, serum triglyceride level, serum high-density lipoprotein cholesterol level, and the presence of hypertension, the adjusted weighted prevalence of periodontitis increased to 29.7% in the IFG 2 group (P = 0.045) and 32.5% in the diabetes group (P < 0.001), compared with the NFG 1 group (24%). The odds ratios for periodontitis with the above-mentioned variables as covariates were 1.42 (95% confidence interval [CI] 1.14–1.77, P = 0.002) in the diabetes group and 1.33 (95% CI 1.01–1.75, P = 0.044) in the IFG 2 group, respectively, compared with the NFG1 group.In conclusion, a higher range of IFG levels as well as diabetes, were positively associated with chronic periodontitis in a representative sample of Korean adults. This study suggests that individuals with a higher range of IFG levels before diabetes are at risk of periodontitis, and may benefit from dental screening.

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Section: Methodsmentioning

confidence: 99%

The Prevalence and Associated Factors of Periodontitis According to Fasting Plasma Glucose in the Korean Adults

2016

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“…In comparison, OGTT is a more difficult and time-consuming test to perform than evaluating HbA1c level. If using FPG only for diagnosis of diabetes, individuals with FPG <126 mg/dL and PPG ≥200 mg/dL may be missed because results from FPG and PPG can show a discordance [11-14]. An advantage of using HbA1c level is that it can be determined by both FPG and PPG exposure [7-9].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Diabetes and Prediabetes according to Fasting Plasma Glucose and HbA1c

et al. 2013

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BackgroundDue to the inconvenience of performing oral glucose tolerance tests and day to day variability in glucose level, glycated hemoglobin (HbA1c) has been recommended by the American Diabetes Association as a method to diagnose diabetes. In addition, the Korean Diabetes Association has also recommended the use of HbA1c as a diagnostic test for diabetes. In this study, we evaluated the prevalence of diabetes according to fasting plasma glucose (FPG) level only or the combination of FPG and HbA1c tests.MethodsData from the 2011 Korea National Health and Nutrition Examination Survey (KNHANES) were analyzed. Among 5,811 subjects aged 30 years or older, 5,020 were selected after excluding the data of fasting time <8 hours, missing values from fasting glucose or HbA1c level, previous diagnosis of diabetes made by physicians, or current use of antidiabetic medications. Diabetes was defined as FPG ≥126 mg/dL, previous diagnosis of diabetes made by a medical doctor, current use of antidiabetic medications, and/or HbA1c ≥6.5%. Prediabetes was defined as FPG of 100 to 125 mg/dL and/or HbA1c of 5.7% to 6.4%.ResultsWhen we used FPG only, the prevalence of diabetes and prediabetes were 10.5% (men, 12.6%; women, 8.5%) and 19.3% (men, 23.8%; women, 14.9%), respectively. When HbA1c was included as a diagnostic test, the prevalence of diabetes and prediabetes increased to 12.4% (men, 14.5%; women, 10.4%) and 38.3% (men, 41%; women, 35.7%), respectively. Participants with HbA1c ≥6.5% and fasting glucose level <126 mg/dL were older and had lower estimated glomerular filtration rate.ConclusionWe concluded that using fasting glucose level only may result in an underestimation of diabetes and prediabetes. HbA1c is an acceptable complementary diagnostic test for diabetes in Korean patients. However, national standardization is needed to order to use HbA1c as a diagnostic method of diabetes and prediabetes.

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“…We also suggest that the FPG level required for a diagnosis of type 2 diabetes mellitus is lower in the Korean and Asian populations than in Western populations [5]. For this reason, Oh et al [7] analyzed the IFG population according to fasting glucose level, as follows: stage 1 IFG (100 to 109 mg/dL) and stage 2 IFG (110 to 125 mg/dL). For subjects in the stage 2 group, poorer metabolic profiles were detected in terms of total cholesterol, triglyceride, and high blood pressure.…”

Section: Screening Of Type 2 Diabetes Mellitusmentioning

confidence: 99%

2011 Clinical Practice Guidelines for Type 2 Diabetes in Korea

Kim

et al. 2011

J Korean Diabetes

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A report on the diagnosis of intermediate hyperglycemia in Korea: A pooled analysis of four community-based cohort studies

Cited by 21 publications

References 29 publications

The Prevalence and Associated Factors of Periodontitis According to Fasting Plasma Glucose in the Korean Adults

The Prevalence and Associated Factors of Periodontitis According to Fasting Plasma Glucose in the Korean Adults

Prevalence of Diabetes and Prediabetes according to Fasting Plasma Glucose and HbA1c

2011 Clinical Practice Guidelines for Type 2 Diabetes in Korea

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