A report on pharmacognostical evaluation of four Adiantum species, Pteridophyta, for their authentication and quality control

Singh, Shweta; Khatoon, Sayyada; Singh, Harsh; Behera, Shashikanta; Khare, Priyanka; Rawat, Ajay Kumar Singh

doi:10.1590/s0102-695x2013005000023

Cited by 18 publications

(12 citation statements)

References 7 publications

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“…Surprising results that was no difference between inhibition zones of methicillin-resistant and methicillin-susceptible strain may be due to the some component of essential oil caused bacterial cell damaged this result is in agreement with [44][45][46]. They found that essential oil caused gross membrane damaged and provoke whole cell lysis of eukaryotic.…”

Section: Discussionsupporting

confidence: 62%

“…The mecA and Bel gene coding for methicillin resistance via penicillin binding protein 2a (PBP2a) are well established and is considered as "gold standard" for detection of methicillin resistance in comparison with phenotypic methods [46,47]. Our results revealed that the inhibitory effect of essential oils on Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis (MRSA) and Gram-negative bacteria Escherichia coli bacteria may be due to reduction or modified of β-lactamse (methicillin) resistance but the actual mechanism is unknown.…”

Section: Discussionmentioning

confidence: 99%

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Antimicrobial, Antiviral Activity and GC-MS Analysis of Essential Oil Extracted from Achillea fragrantissima Plant Growing In Sinai Peninsula, Egypt

Zeedan¹

2014

J Microb Biochem Technol

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Medicinal plants are considered new resources for producing agents that could act as alternatives to antibiotics in treatment of antibiotic-resistant bacteria. The present study aimed to evaluate the efficacy of essential oil extracted from Achillea fragrantissima plant growing in Egypt for antimicrobial, antiviral activities and chemical composition analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). We also performed determination of essential oil antimicrobial activity by agar desk diffusion method and Minimal Inhibitory Concentration (MIC). Also, antiviral activity on ORF virus by pock reduction test was performed. It was reduced virus titer from 5.9 to 1.00 at 180 minutes. Detection of beta lactams resistant bacteria (Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis (MRSA) and Gram-negative bacteria Escherichia coli) by PCR with primers of mecA gene and Bela gene. The essential oil obtained by hydrodistillation was analyzed by GC-MS. The major components were found to be Santolina triene (1.97%), 2,5,5-trimethyl-3,6-heptadien-2-ol (8.23%) Eucalyptol 8.17, trans-2,7-Dimethyl-4,6octadien-2-ol (24.40%), 1,5-Heptadien-4-one-3,6-trimethyl (7.65%), Artemisia alcohol (3.49%), à Thujone (33.97%), Cissabinol (1.92%), Lavandulol (0.71%), 2-Octen-4-ol, 2-methyl (2.02%), 3-Cyclohexen1ol,4-methyl1 (1 methylethyl) (CAS) (2.15%), à terpineol ( 0.05% ), Estragole (0.71%) Lavandulyl acetate (0.49%), Sabinyl acetate (2.12 %), Germacrened (0.94%). Finally, our study proved that the essential oil has bactericidal effect on some bacterial resistant antibiotic (Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis (MRSA) and Gram-negative bacteria Escherichia coli ) as well as antiviral activity on ORF virus but it is still need further extensive studies for safety and drug interaction. Antimicrobial, Antiviral Activity and GC-MS Analysis of Essential IntroductionMedicinal plants still constitute one of the major source of drugs in modern as well as traditional medicine throughout the world [1,2]. Since a long period of time, plants have been a valuable source of natural products for maintaining animals and human health [2,3]. The development of multidrug-resistant(MDR) bacteria takes place because of the accumulation of different antibiotic resistance mechanisms inside the same strain which able to live in the presence of antibiotics drugs so that standard treatments become ineffective [4,[14][15][16]. Although, the pharmacological companies have produced a number of new antibiotics recently, but even then microorganism resistance to antibiotics increased throughout the world [5,7]. This situation has attract attention of researchers towards herbal products for developing and improve the antibacterial drugs quality [6,7].Natural products of higher plants may possess a new source of antimicrobial agents with possibly novel mechanisms for treatment of infectious diseases [8,9]. Medicinal plants contain active principles which can be used as alternative effective herbal dru...

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Antimicrobial, Antiviral Activity and GC-MS Analysis of Essential Oil Extracted from Achillea fragrantissima Plant Growing In Sinai Peninsula, Egypt

Zeedan¹

2014

J Microb Biochem Technol

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“…Oral administration of the aqueous extract of the trunk barks of S. campanulata P. Beauv at doses of 200, 400 and 800 mg/kg body weight over a period of 8 days influenced the copulatory activity of normal and sexually experienced male Wistar albino rats. Compared with the animals in the negative control groups, the effects of the extract on the sexual behavior of the treated rats were materialized by stimulation of sexual motivation, effect confirmed by the increase in the frequencies of erections and mounts as well as the decrease in the latency of mount; stimulation of sexual performance, effect confirmed by the increase in the frequency of intromissions as well as the decrease of the latency of intromission; stimulation of sexual pleasure by an increase in the frequency of ejaculation and the latency of ejaculation, effect confirmed by the increase of the frequency of ejaculations and the increase of the latency of ejaculation (Singh et al, 2013b). It can be concluded that the aqueous extract of the trunk barks of S. campanulata P. Beauv have a pro-ejaculatory aphrodisiac effect.…”

Section: Resultsmentioning

confidence: 88%

Evaluation of aphrodisiac properties of the aqueous extract of the trunk barks of Spathodea campanulata P. Beauv. (Bignoniaceae) on albino rats (Rattus norvegicus)

Clovis¹,

Yaya²,

Nga³

et al. 2019

J. Med. Plants Res.

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Spathodea campanulata P. Beauvois (Bignoniaceae) is a tree from the tropical and subtropical forests of Africa, used in folk medicine for the treatment of several diseases such as gastric pain, rheumatism, lumbago, cataracts and some intestinal parasites. In West Cameroon, traditional healers use a decoction of the bark of the trunk as an aphrodisiac in males. The objective of the present study was to evaluate the aphrodisiac activity of the aqueous extract of the trunk barks of S. campanulata in male rats. The male rats were divided into five lots: A, B, C, D and E of six animals each. Lot A received 5 ml/kg of distilled water daily for 8 days (negative control). Lot B received 5 mg/kg of Sildenafil Citrate (Viagra®) daily for 8 days (positive control). Lots C, D and E received 200, 400 and 800 mg/kg, respectively of the aqueous extract of the trunk barks of S. campanulata daily for 8 days. On the first, fourth and eighth day of administration, the copulatory parameters were observed and recorded. The extract induced an increase in erectile function stimulation through the significant increase (p<0.001) in the number of erections, the frequency of mount and a decrease in mount latency, reflecting an increase in sexual stimulation; an increase in the frequency of intromission (p<0.001) and a decrease in intromission latency, reflecting a stimulation of sexual performance. There was also an increase in ejaculation frequency and ejaculation latency (p<0.001). These results indicate a pro-ejaculatory aphrodisiac potential of the aqueous extract of the trunk barks of S. campanulata in male rats and would justify the empirical use of this plant in the treatment of erectile dysfunction in humans, in traditional medicine.

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“…Adiantum capillus-veneris is used as traditional medicine for curing various diseases 6 . In Ayurvedic system of medicine for certain health conditions such as cold, tumors of the spleen, liver, skin diseases, bronchitis and inflammation 7 . Capillaries are a main ingredient of Adiantum capillus used as a cough syrup and fever as well as used as a stimulant, emollient and purgative also used to improve appetite, digestion, stimulate renal function, regulate menstruation, and facilitate childbirth depurative, emetic, emollient, febrifuge, galactagogue, alopecia and tonic.…”

Section: Introductionmentioning

confidence: 99%

“…The extracts of the Adiantum leaves have anti-inflammatory, analgesic, anti-microbial activities 7. The hydro-alcoholic extract of leaves has strong anti-urolithic properties and isolated vascular endothelial growth factor and transforming growth factor beta-1 proteins in normal and streptozotocin-induced diabetic rats, during treatment of formulations of Aloe Vera, Henna, Adiantum capillus-veneris, and Myrrha usually claimed 2,10 have been reported very good antidiabetic as well as low side effect at the different dose of aqueous extracts and methanolic extract, Hair growth-promoting activity was reported by 11 on albino mice using a testosterone-induced alopecia model and methanolic extract of whole plant showed the antibacterial activity 11 .…”

Section: Introductionmentioning

confidence: 99%

Antinociceptive Activity of Adiantum Capillus in Experimental Animals

Khan¹,

Jawla²,

Hussain³

2019

Int. Res. J. Pharm.

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In present study 50% ethanolic extract of whole plant of Adiantum capillus (ACE) was evaluated for its analgesic and anti-inflammatory effects in animals at different doses 100, 200 and 300 mg/kg by different method. Eddy's hot plate method, writhing test, formalin test and carrageenan induced revealed that ACE possessed varying degree of analgesic and anti-inflammatory activity significant at 100, 200 and 300 mg/kg and highly significant at 300 mg/kg in comparison to control. In acetic acid induced writhing test, maximum inhibition of writhing was observed at 300 mg/kg where the number of writhes decreased from 40.32 to 18.32 indicating 54.56% inhibition. While formalin induced pain (0.05 ml of 2.5%) was significantly blocked only at higher dose (300 mg/kg) in first phase. ACE significantly blocked pain emanating from inflammation at all the doses in second phase. The reaction time in hot plate was increased significantly and dose dependently whereas pretreatment with diclofenac sodium reduced the analgesic potentials of ACE.

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A report on pharmacognostical evaluation of four Adiantum species, Pteridophyta, for their authentication and quality control

Cited by 18 publications

References 7 publications

Antimicrobial, Antiviral Activity and GC-MS Analysis of Essential Oil Extracted from Achillea fragrantissima Plant Growing In Sinai Peninsula, Egypt

Antimicrobial, Antiviral Activity and GC-MS Analysis of Essential Oil Extracted from Achillea fragrantissima Plant Growing In Sinai Peninsula, Egypt

Evaluation of aphrodisiac properties of the aqueous extract of the trunk barks of Spathodea campanulata P. Beauv. (Bignoniaceae) on albino rats (Rattus norvegicus)

Antinociceptive Activity of Adiantum Capillus in Experimental Animals

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