A rare case of uterine leiomyosarcoma: a case report

Vellanki, Venkata Sujatha; Rao, Meiying; Sunkavalli, Chinna Babu; Chinamotu, Rao N; Kaja, Shailaja

doi:10.1186/1752-1947-4-222

Cited by 23 publications

(23 citation statements)

References 5 publications

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“…Senol et al reported a very large leiomyosarcoma in a 62-year-old female presenting with abdominal mass, fatigue, and associated tenderness [ 16 ]. Vellanki et al also reported a uterine leiomyosarcoma in a 40-year-old nulliparous woman presenting with abdominal pain and no menstrual irregularity and no vaginal bleeding [ 17 ]; our patient had no vaginal bleeding and no abdominal pain, just complains from 3 months' period of abdominal distension attributed to gastrointestinal diseases. However, abdominal distension is usually attributed to gastrointestinal diseases which leads to misdiagnosis, mismanagement, and overgrowth of tumor [ 18 ].…”

Section: Discussionmentioning

confidence: 56%

Misdiagnosis of a Giant Uterine Leiomyosarcoma: Clinic and Image Challenges

Agah

Karimzadeh

Ahmadi

2017

Case Reports in Oncological Medicine

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A 41-year-old woman (G3P2L2Ab1) was referred to gynecology clinic with chief complaints of abdominal distension and localized abdominal wall pruritus for three months. She was misdiagnosed with gastrointestinal disorder and ultimately had undergone imaging. Ultrasonography and computed tomography (CT) scan disclosed a huge solid-cystic mass originating from the ovary. On clinical examination the patient had no pain or tenderness and no gynecologic complaints. Laboratory tests showed normal tumor markers and hemoglobin at 8 g/dl. Laparotomy was carried out as diagnosis of ovarian serous cyst adenoma, but a huge tumor with attachment to uterus and ovaries and extension to pelvic floor, peripheral tissues of ureter, and upper abdomen was found. Hysterectomy with bilateral salpingooophorectomy was done. Pathology report demonstrated uterine leiomyosarcoma measuring 40 centimeters and weighing 10 kilograms. In conclusion, as pelvic masses even in a large size may present unspecific symptoms misdiagnosis may occur which lead to overgrowth, local invasion, or other complications. So, it is rather to suggest ultrasonography in patients with persistent abdominal or pelvic symptoms and if needed, more exact diagnostic modalities like magnetic resonance imaging (MRI) could be offered to avoid misdiagnosis and mismanagement.

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Section: Discussionmentioning

confidence: 56%

Misdiagnosis of a Giant Uterine Leiomyosarcoma: Clinic and Image Challenges

Agah

Karimzadeh

Ahmadi

2017

Case Reports in Oncological Medicine

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“…[10] Vellanki et al reported a case of pelvic mass with raised CA125, which on histology was diagnosed as uterine leiomyosarcoma. [11] Local control of soft tissue sarcomas is usually achieved with surgical resection. Pre operative planning based upon radiographic and pathologic information is important to ensure adequate surgical margins.…”

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma with unknown primary

Khare¹,

Airun²,

Sharma³

et al. 2017

APALM

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Leiomyosarcoma is a malignant tumor which does not arise from the leiomyoma. Leiomyosarcoma is an extremely rare form of cancer and accounts for 5-10% of soft tissue sarcomas, which are in themselves relatively rare. This case report shows unusual presentation of the multifocal leiomyosarcoma along with diagnostic dilemma. The prognosis and treatment modality are also discussed in the discussion.Keywords: Leiomyosarcoma, Multifocal, Poor Prognosis tumor and leiomyosarcoma. Further IHC panel was applied.

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“…In postmenopausal women, the incidence of sarcoma is 1%–2% and they have a rapid doubling time of 4 weeks 2. Uterine leiomyosarcoma behave aggressively with a high rate of recurrence and poor prognosis 3.…”

Section: Differential Diagnosismentioning

confidence: 99%

Management of a giant uterine leiomyoma

Lim¹,

Tan

Chia

et al. 2018

BMJ Case Reports

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Uterine leiomyomas are the most common tumours arising from the female reproductive tract. However, giant myomas, which are greater than 11.4 kg in weight, are exceedingly rare. They may cause a pressure effect on surrounding organs, heart and lungs, which can be potentially life threatening. We present a case of a 53-year-old woman with a massive uterine mass complicated by restrictive lung disease. She underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy with frozen section and reconstruction of the abdominal wall by the gynaecologists and plastic surgeons. The excised specimen weighed 27.8 kg, which included a benign subserosal leiomyoma measuring 64 by 50.5 by 15 cm. Intraoperative blood loss was 7 L and her postoperative recovery was complicated by coagulopathy and haemorrhagic shock. This case illustrates the pivotal role of multidisciplinary care in the management of complicated surgical patients and the need for careful perioperative care.

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A rare case of uterine leiomyosarcoma: a case report

Cited by 23 publications

References 5 publications

Misdiagnosis of a Giant Uterine Leiomyosarcoma: Clinic and Image Challenges

Misdiagnosis of a Giant Uterine Leiomyosarcoma: Clinic and Image Challenges

Leiomyosarcoma with unknown primary

Management of a giant uterine leiomyoma

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