Misdiagnosis of a Giant Uterine Leiomyosarcoma: Clinic and Image Challenges

Agah, Jila; Karimzadeh, Sedighe; Ahmadi, Fateme Moharrer

doi:10.1155/2017/3568328

Cited by 3 publications

(3 citation statements)

References 16 publications

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“…Although there is ambiguity in the diagnostic accuracy of individual characteristics, MRI is still the preferred imaging method for in-depth evaluation of uterine fibroid tumors and depicting the local spread of malignant diseases [7]. Compared to MRI, the main advantage of CT scanning is that CT is less expensive and easier for patients to accept [8].…”

Section: Discussionmentioning

confidence: 99%

CT diagnosis of uterine leiomyosarcoma: a case report

Wang,

Wu,

et al. 2024

Radiology Science

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Background: A uterine leiomyosarcoma is a relatively rare malignant tumor of the uterus with a high degree of malignancy that is prone to distant metastasis and recurrence in the early stages, and therefore has a poor prognosis. Plain and enhanced CT scans are important for the early diagnosis of uterine leiomyosarcoma. Case report: We report the case of a 47-year-old woman with a uterine leiomyosarcoma. A preoperative plain CT scan showed significant uterine enlargement, whereas an enhanced CT scan showed an uneven and significantly enhanced mass. A large mass was observed in the lower and middle parts of the abdomen intraoperatively. The large mass in the abdominal and pelvic cavities was a uterine mass with bilateral adnexal lesions, approximately 20 cm × 20 cm × 15 cm in size. Bilateral retroperitoneal masses were palpated. A total hysterectomy, left salpingectomy, right adnexectomy, and resection of the retroperitoneal mass were performed. The pathologic diagnosis was uterine leiomyosarcoma with bleeding and necrosis. Conclusions: Diagnosis of uterine leiomyosarcoma lacks clinical specificity. Imaging is helpful for early diagnosis, treatment, disease course assessment, and efficacy evaluation. Ultimately, a pathologic examination and biopsy are required to confirm the diagnosis.

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Section: Discussionmentioning

confidence: 99%

CT diagnosis of uterine leiomyosarcoma: a case report

Wang,

Wu,

et al. 2024

Radiology Science

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“…However, our results differed from those of previous reports. In humans, heterogeneous enhancement is caused by haemorrhage, necrosis and calcification (Agah et al., 2017 ). In this study, necrosis or cystic areas were present in leiomyoma, which may have affected the enhancement pattern.…”

Section: Discussionmentioning

confidence: 99%

Computed tomography and magnetic resonance imaging findings in dogs with vaginal leiomyoma and leiomyosarcoma

Tanaka

Noguchi

Wada

et al. 2022

Veterinary Medicine & Sci

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Background: In humans, magnetic resonance imaging (MRI) is preferred over computed tomography (CT) for the assessment of pelvic lesions. Although CT findings of several pelvic tumours have been reported in veterinary medicine, MRI findings are limited. Objectives:The purpose of this study was to retrospectively compare the CT and MRI findings in dogs with vaginal leiomyoma and leiomyosarcoma.Methods: This retrospective study of five dogs compared the CT and MRI findings of intrapelvic lesions, including vaginal leiomyoma (n = 4) and leiomyosarcoma (n = 1). No invasion of the surrounding tissue was detected on histopathological examination. In this retrospective study, the following parameters of CT and MRI were recorded for each dog: the border between the lesion and the adjacent pelvic organs, including the prostate, rectum or urethra; signal intensity (SI) of the lesion; enhancement pattern; presence of haemorrhage; necrosis or cystic areas and lymphadenopathy. Because SI on MRI is affected by cell density, tumour cell density was analysed using a microscope slide. Results:In vaginal leiomyoma, the border between the lesion and the surrounding pelvic organ tends to be clearer on MRI than on CT. In vaginal leiomyosarcoma, the border was comparable between MRI and CT. Each lesion showed heterogeneous enhancement on CT and MRI scans. In each lesion, the assessment of haemorrhage, necrosis, cystic areas and lymphadenopathy was comparable between MRI and CT. The SI of the lesion on T2WI of the vaginal leiomyoma and leiomyosarcoma were hyperintense in four cases (4/4; 100%) and mixed intense in one case (1/1; 100%), respectively.The cell density of leiomyosarcoma is higher than that of leiomyomas.

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“…Due to the position of the ovaries, which is deep down the pelvis, the diagnosis of this cancer may be missed in its early stages [9] . Also, it may mimic symptoms of other disorders such as gastrointestinal or uterine abnormalities which may delay its diagnosis [10,11] . Ovarian germ cell tumors result from primordial cells and may be malignant or benign.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Malignant Ovarian Germ Cell Tumor and Distribution of Demographic Features in a Main Tertiary Hospital in Iran

Akhavan

Agah

Alipour

2018

J Obstet Gynecol Cancer Res

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Misdiagnosis of a Giant Uterine Leiomyosarcoma: Clinic and Image Challenges

Cited by 3 publications

References 16 publications

CT diagnosis of uterine leiomyosarcoma: a case report

CT diagnosis of uterine leiomyosarcoma: a case report

Computed tomography and magnetic resonance imaging findings in dogs with vaginal leiomyoma and leiomyosarcoma

Frequency of Malignant Ovarian Germ Cell Tumor and Distribution of Demographic Features in a Main Tertiary Hospital in Iran

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