A Rare Case of Diffuse Pulmonary Nodules in a Patient with Adult-onset Still's Disease

Qi, Haifeng; Yin, Chenghong; Xiao, Hongli; Duan, Ting

doi:10.2169/internalmedicine.53.1868

Cited by 6 publications

(5 citation statements)

References 13 publications

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“…Rare cases of bilateral pulmonary nodules have been reported [56,57]. Parenchymal lung involvement was classified into 2 groups: predominant airway involvement (bronchiolitis and bronchitis) and predominant interstitial lung disease (nonspecific interstitial pneumonia, organizing pneumonia, or unclassifiable interstitial pneumonia) [55].…”

Section: Discussionmentioning

confidence: 99%

Elderly-onset adult Still’s disease

et al. 2021

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Adult-onset Still's disease is a rare inflammatory disorder usually affecting young adults. Elderly-onset Still's disease (EOSD) is reported in some cases, commonly in Japan, the USA and Europe. One of the most commonly used criteria for diagnosing EOSD is Yamaguci criteria. In elderly patients more severe course of the disease and more complications may be expected than in the younger group of patients with Still's disease. The lungs involvement is rather rare manifestation of this disease. In our article we discuss the problem of both the development of Still's disease in the elderly and interstitial lung changes in the course of the disease, based on available literature and own cases from one centre.

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Section: Discussionmentioning

confidence: 99%

Elderly-onset adult Still’s disease

et al. 2021

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“…To the best of our knowledge, the association between lung diseases and AOSD has been reported numerous times (5,15,16), and pleuritis associated with AOSD has been widely reported, ranging between 12 and 53% in various studies (17,18). Pleuritis is usually followed by pleural effusion (12).…”

Section: Discussionmentioning

confidence: 99%

Adult onset Still's disease accompanied by acute respiratory distress syndrome: A case report

Wang

Huang

et al. 2016

Experimental and Therapeutic Medicine

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Abstract. Adult onset Still's disease (AOSD) is a systemic inflammatory disorder characterized by rash, leukocytosis, fever and arthralgia/arthritis. The most common pulmonary manifestations associated with AOSD are pulmonary infiltrates and pleural effusion. The present study describes a 40-year-old male with AOSD who developed fever, sore throat and shortness of breath. Difficulty breathing promptly developed, and the patient was diagnosed with acute respiratory distress syndrome (ARDS). The patient did not respond to antibiotics, including imipenem, vancomycin, fluconazole, moxifloxacin, penicillin, doxycycline and meropenem, but was sensitive to glucocorticoid treatment, including methylprednisolone sodium succinate. ARDS accompanied by AOSD has been rarely reported in the literature. In conclusion, in a patient with ARDS who does not respond to antibiotic treatment, the involvement of AOSD should be considered.

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“…Accordingly, its diagnosis should rely on clinical suspicion and is often supported by the use of classification criteria [12,13] . The classic presentation of AOSD includes fever, a 'salmon-pink' rash, arthralgia, arthritis, and lymphadenopathy while serositis and other atypical manifestations are seldom reported and are considered not to be major diagnostic criteria [12][13][14][15] .…”

Section: Consanguinity Of Parentsmentioning

confidence: 99%

Idiopathic chronic polyserositis with massive ascites responding to colchicine in an adult: A case report

Fernández-Ayala

Carrascosa

Salcines-Caviedes

2014

CRIM

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Objective: While there are many different causes of ascites, most cases are due to cirrhosis. However, a serum/ascites albumin gradient <1.1 indicates that the ascites is not induced by portal hypertension and mandates a search for other etiologies, including causes of serositis. We describe a 70-year-old patient with persistent ascites and pleuropericarditis who underwent a successful outcome while on colchicine treatment. Methods:This study was delineated on a case-report basis. Besides supportive care measures, we performed a comprehensive clinical and complementary assessment of the patient, which included laboratory tests, imaging techniques, endoscopic evaluation, full microbiological and pathological studies, diagnostic laparoscopy and thoracoscopy, and genetic testing for autoinflammatory diseases. Results:Diagnostic workup failed to demonstrate the presence of an underlying etiologic disorder. Large-volume paracentesis was performed once monthly during 13 consecutive months due to painless, massive accumulation of peritoneal fluid. Eventually, colchicine therapy induced a dramatic response with clinical and radiological disappearance of polyserositis within three months of starting on the drug. While on colchicine, the disease has not recurred throughout a thirty two months period of follow-up so far. To our knowledge, the occurrence of idiopathic, chronic refractory ascites and pleuropericarditis resolved under colchicine treatment in an adult not diagnosed with Familial Mediterranean Fever is an exceptional event.Conclusion: We suggest that in adult patients suffering from idiopathic chronic polyserositis including massive ascites the possible existence of an underlying autoinflammatory condition should be sought. In such a case, a colchicine trial might be regarded as an early suitable therapeutic option.

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A Rare Case of Diffuse Pulmonary Nodules in a Patient with Adult-onset Still's Disease

Cited by 6 publications

References 13 publications

Elderly-onset adult Still’s disease

Elderly-onset adult Still’s disease

Adult onset Still's disease accompanied by acute respiratory distress syndrome: A case report

Idiopathic chronic polyserositis with massive ascites responding to colchicine in an adult: A case report

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