1987
DOI: 10.1097/00000421-198706000-00019
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A Randomized Trial of High Dose Bolus Metoclopramide Versus Low-Dose Continuous Infusion Metoclopramide in the Prevention of Cisplatin-Induced Emesis

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Cited by 12 publications
(6 citation statements)
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“…In the BG, doses were: 2 mg/kg metoclopramide (Dana et al . , Agostinucci et al . ), 20 mg metoclopramide (Egerton‐Warburton & Povey ), 1 mg/kg metoclopramide (Navari , Mori et al .…”
Section: Resultsmentioning
confidence: 96%
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“…In the BG, doses were: 2 mg/kg metoclopramide (Dana et al . , Agostinucci et al . ), 20 mg metoclopramide (Egerton‐Warburton & Povey ), 1 mg/kg metoclopramide (Navari , Mori et al .…”
Section: Resultsmentioning
confidence: 96%
“…Most studies collected the sample size in terms of number of patients studied (ranging from 9–154 patients), and only one study collected the number of neoplastic treatment per patients, in which the authors compared the efficacy of metoclopramide in 32 courses of chemotherapy of 16 patients (Dana et al . ).…”
Section: Resultsmentioning
confidence: 97%
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“…In these trials, 8/21 (38,,) of patients given metoclopramide were free from nausea and vomiting but none of the patients given prochlorperazine or placebo were symptom free. A number of studies have assessed the efficacy of high-dose metoclopramide administered as a continuous infusion (29)(30)(31)(32). This method of administration has a number of proposed advantages: rapid attainment and maintenance of therapeutic serum concentrations and prevention of drug accumulation (reduced toxicity).…”
Section: Conventional Anti-emetic Drug Therapymentioning
confidence: 99%