A Prospective Study of Fractionated Dual‐Wavelength Picosecond Laser in Treating Acne Scar

Abstract

Background and Objectives The picosecond (PICO) laser has been a new and promising device. But, so far, there have not been many prospective studies investigating the efficacy in acne scar treatment. This study evaluated the efficacy and safety of the dual‐wavelength picosecond laser in the treatment of acne scar. Study Design/Materials and Methods A total of 20 patients with skin type III–IV were enrolled in this study. Eighteen patients completed the study. All patients completed six treatment sessions within a 1‐month interval. All patients were treated using both 532 and 1,064 nm fractionated dual‐wavelength picosecond handpieces. In evaluation, Goodman and Baron's quantitative global acne scarring grading system (GSS) was scored by two physicians. Patients also judged the results themselves by Visual Analog Scale (VAS) and pain score. Results The average baseline score of GSS quantity and quality were 15.22 and 3.00, respectively. The final scores were 10.61 and 2.33. The average baseline of patient VAS score was 4.28. The final score was 2.00. All scores achieved statistical significance (P < 0.05). No serious long‐term side effects were recorded. Conclusion Acne scar treatment with the fractionated dual‐wavelength picosecond laser has shown both efficacy and safety in this study. Lasers Surg. Med. © 2020 Wiley Periodicals, Inc.

A Systematic Review of Picosecond Laser in Dermatology: Evidence and Recommendations

“…Picosecond laser for acne scars has been studied in one case series; four retrospective reviews; five prospective open-label clinical trials; and one randomized, split-face, comparison trial versus fractional 1550 nm erbium fiber laser involving a cumulative total of 194 subjects [8,9,63,65,66,71,72]. Additionally, there has been one case series of 16 patients studying picosecond laser treatment of hyperpigmented scars; one retrospective review of 24 patients with hypertrophic scars; one retrospective review of nine patients with atrophic surgical scars which was subsequently extended by the same group to include an additional eight subjects with atrophic scars and eight subjects with hypertrophic surgical scars; and one randomized, evaluator-blinded, split-body comparison trial of fractionated picosecond Nd:YAG laser versus 1565 nm fractional non-ablative laser for the treatment of striae alba in 20 subjects [64,[67][68][69][70].…”

Picosecond‐Domain Fractional Laser Treatment Over Hyaluronic Acid Fillers: In Vivo and Clinical Studies

“…Ablative lasers were superseded by fractionated lasers used to treat small areas of skin between the untreated zones, with which the side effects and downtime were significantly reduced. Recently, picosecond-domain lasers, conventionally developed to remove tattoos and pigmented lesions, have been modified to create fractionated arrays and are used to treat photoaged skin and acne scarring [8][9][10][11][12]. Although noninvasive facial resurfacing has many benefits, it may be necessary to perform combined treatments to optimize the outcomes.…”

Contemporary model of dealing with scars in cosmetology and aesthetic medicine

“…Do oceny skuteczności lasera wykorzystano ilościowy globalny system klasyfikacji blizn potrądzikowych GSS firmy Goodman i Baron oraz subiektywną ocenę pacjetów według skali VAS (visual analog scale). Nie odnotowano żadnych poważnych długoterminowych skutków ubocznych, a leczenie blizn potrądzikowych za pomocą frakcjonowanego lasera pikosekundowego o podwójnej długości fali wykazało w tym badaniu zarówno skuteczność, jak i bezpieczeństwo [26].…”