A primary method for determination of optical parameters of turbid samples and application to intralipid between 550 and 1630nm

Chen, Cheng; Lu, Jun Q.; Ding, Huafeng; Jacobs, Kenneth M.; Du, Yong; Hu, Xin

doi:10.1364/oe.14.007420

Cited by 80 publications

(64 citation statements)

References 27 publications

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“…2(c) where we calculate g for varying particle diameter, this particle diameter corresponds to the scattering anisotropy g = 0.35 ± 0.03. This value agrees very well with previously reported measurements of g for Intralipid at 1300 nm g = 0.32 ± 0.07 [20]. Fig.…”

Section: Intralipidsupporting

confidence: 93%

Determination of the scattering anisotropy with optical coherence tomography

Kodach¹,

Faber²,

Marle³

et al. 2011

Opt. Express

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Abstract:In this work we demonstrate measurements with optical coherence tomography (OCT) of the scattering phase function in the backward direction and the scattering anisotropy parameter g. Measurements of the OCT attenuation coefficient and the backscattering amplitude are performed on calibrated polystyrene microspheres with a time-domain OCT system. From these measurements the phase function in the backward direction is determined. The measurements are described by the single scattering model and match Mie calculations very well. Measurements on Intralipid demonstrate the ability to determine the g of polydisperse samples and, for Intralipid, g = 0.35 ± 0.03 is measured, which is well in agreement with g from literature. These measurements are validated using the Intralipid particle size distribution determined from TEM measurements. Measurements of g and the scattering phase function in the backward direction can be used to monitor changes in backscattering, which can indicate morphological changes of the sample or act as contrast enhancement mechanism.

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Section: Intralipidsupporting

confidence: 93%

Determination of the scattering anisotropy with optical coherence tomography

Kodach¹,

Faber²,

Marle³

et al. 2011

Opt. Express

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“…Overall, our results are in good agreement with other measured data. The scattering values reported by Chen et al 35 are 30% lower than our and other published results and are not included in the diagram. Figure 9 also shows the reduced scattering coefficient calculated by Mie theory using our particle size measurement, as well as values derived from the van Staveren et al 19 Mie theory fit.…”

Section: Discussioncontrasting

confidence: 71%

Characterizing liquid turbid media by frequency-domain photon-migration spectroscopy

et al. 2009

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We present a wavelength-tunable frequency-domain instrument for the characterization of liquid turbid media. The instrument employs a tunable titanium-sapphire laser modulated by an acousto-optic modulator. The absorption and reduced scattering coefficient of Intralipid(R) 20%, diluted to concentrations of 0.94 to 4.00%, are measured over the wavelength range 710 to 850 nm at 10-nm intervals. The standard measurement errors for the absorption and reduced scattering coefficients are 1 and 2.5%, respectively. Extrapolation to 0% Intralipid(R) concentration gives an absorption coefficient that closely follows that of water, overestimating the absorption of pure water by less than 10%. The reduced scattering coefficient is compared at 750 nm with published results and is found consistent within the experimental error. We compare the reduced scattering coefficient to an estimate based on Mie theory and find the reduced scattering coefficient underestimated the Mie theory result by about 9%.

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“…By comparison, we find that g agrees with the estimation but m s is underestimated. Nevertheless, m s is close to Moes's result (38.6 mm À1 )[23] and Chen's result (30 mm À1 )[24]Curves of diffuse reflectance vs. x for Intralipid solution with different concentrations. The raw data are plotted with circle label and the fitted results generated by our algorithm are plotted with solid line.…”

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confidence: 87%