A possible relationship of human leucocyte antigens with psoriasis vulgaris and geographic tongue

Picciani, Bruna Lavinas Sayed; Carneiro, Sueli; Sampaio, Ana Luisa; Santos, Bruna Michalski dos; Santos, Vanessa Costa; Gonzaga, H.F.S.; Oliveira, Jorge; Pôrto, Luís Cristóvão; Dias, Eliane Pedra

doi:10.1111/jdv.12691

Cited by 15 publications

(11 citation statements)

References 47 publications

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“…Similar to GT, psoriasis is a dermal, inflammatory, genetic, and immunological disease with much clinical importance . Studies show that GT is the most common oral lesion associated with psoriasis based on the microscopic similarity between these conditions and the presence of a common genetic marker, HLA‐Cw6 . Some authors have questioned the diagnosis of GT as oral psoriasis since there are some patients who present with GT but not psoriasis …”

Section: Discussionmentioning

confidence: 99%

Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis

et al. 2017

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GT is a symptomatic lesion with a thick halo. In contrast, psoriatic patients are frequently asymptomatic and exhibit severe lesions with greater loss of papillae that are associated with severe FT. The present study is the first to demonstrate clinical differences in the GT of patients with and without psoriasis, suggesting that some GT cases may represent true oral psoriasis and some cases may represent only GT.

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Section: Discussionmentioning

confidence: 99%

Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis

et al. 2017

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“…19,54 The serologic equivalent for these alleles (HLA-B*57 e -B*58) is the HLA-B17 antigen. Possibly this may explain the association between psoriasis and geographic tongue, respectively, with these alleles.…”

Section: Histopathologic and Immunogenetic Similarities Between Geogrmentioning

confidence: 99%

“…Possibly this may explain the association between psoriasis and geographic tongue, respectively, with these alleles. 54 …”

Section: Histopathologic and Immunogenetic Similarities Between Geogrmentioning

confidence: 99%

Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review

Picciani

Domingos

Teixeira‐Souza

et al. 2016

An. Bras. Dermatol.

122

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Geographic tongue is a chronic, inflammatory, and immune-mediated oral lesion of unknown etiology. It is characterized by serpiginous white areas around the atrophic mucosa, which alternation between activity, remission and reactivation at various locations gave the names benign migratory glossitis and wandering rash of the tongue. Psoriasis is a chronic inflammatory disease with frequent cutaneous involvement and an immunogenetic basis of great importance in clinical practice. The association between geographic tongue and psoriasis has been demonstrated in various studies, based on observation of its fundamental lesions, microscopic similarity between the two conditions and the presence of a common genetic marker, human leukocyte antigen (HLA) HLA-C*06. The difficulty however in accepting the diagnosis of geographic tongue as oral psoriasis is the fact that not all patients with geographic tongue present psoriasis. Some authors believe that the prevalence of geographic tongue would be much greater if psoriatic patients underwent thorough oral examination. This study aimed to develop a literature review performed between 1980 and 2014, in which consultation of theses, dissertations and selected scientific articles were conducted through search in Scielo and Bireme databases, from Medline and Lilacs sources, relating the common characteristics between geographic tongue and psoriasis. We observed that the frequency of oral lesions is relatively common, but to establish a correct diagnosis of oral psoriasis, immunohistochemical and genetic histopathological analyzes are necessary, thus highlighting the importance of oral examination in psoriatic patients and cutaneous examination in patients with geographic tongue.

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“…Several studies have demonstrated associations between BMG and psoriasis, suggesting that BMG is a form of oral psoriasis (6)(7)(8). Emotional stress and other environmental factors may be responsible for different types of diseases.…”

Section: Discussionmentioning

confidence: 99%

“…While most epidemiological studies report a mean prevalence of 0.78 to 6.8% (2)(3)(4)(5), the etiology and pathogenesis of BMG remain obscure. In addition to psoriasis, it has been implied that BMG is an oral manifestation of this cutaneous disease (6)(7)(8)(9), and several authors have suggested the presence of a relationship between psoriasis and BMG, fissured tongue, and geographic stomatitis (6)(7)(8)(9). Emotional stress has been reported to be a triggering factor in these conditions.…”

Section: Introductionmentioning

confidence: 99%

Avaliação do traço e estado de ansiedade em pacientes com Glossite Migratória Benigna

Gonzaga

Aguiar

Jorge³

et al. 2016

Rev. Bras. Odontol.

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ResumoObjetivo: avaliar estado e traço de ansiedade em pacientes com glossite migratória benigna (GMB). O estudo consistiu de 78 pacientes com GMB, apresentando ou não ocorrência simultânea de língua fissurada. Um grupo controle de 48 pacientes, sem lesões orais e/ou cutâneas, também foi incluído no estudo. Foi aplicado o Inventário de Traço-Estado de Ansiedade (STAI). Resultados: estado moderado e pontuações de ansiedade-traço foram observados nos grupos. Não houve diferenças estatisticamente significativas nos escores de ansiedade entre os grupos GMB e controle. Conclusão: a ansiedade não parece desempenhar um papel significativo na GMB, apesar dos níveis moderados observados em pacientes com GMB. No entanto, o estado emocional pode ser um fator determinante para as diferentes formas de manifestações de GMB. Palavras-chave: ansiedade; glossite migratória benigna; língua fissurada. AbstRActObjective: To assess state and trait anxiety in patients with benign migratory glossitis (GMB). The study consisted of 78 patients with GMB, presenting or not simultaneous occurrence of fissured tongue. A control group of 48 patients without oral lesions and / or skin, was also included in the study. Inventory -Trait State Anxiety (STAI) was applied. Results: moderate state and trait anxiety scores were observed in groups. There were no statistically significant differences in anxiety scores between the GMB and control groups. Conclusion: The anxiety seems to play a significant role in the GMB, despite moderate levels observed in patients with GMB. However, the emotional state can be a determining factor for the different forms of manifestations of GMB.

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A possible relationship of human leucocyte antigens with psoriasis vulgaris and geographic tongue

Cited by 15 publications

References 47 publications

Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis

Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis

Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review

Avaliação do traço e estado de ansiedade em pacientes com Glossite Migratória Benigna

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