Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis

Picciani, Bruna Lavinas Sayed; Santos, Vanessa de Carla Batista dos; Teixeira‐Souza, Thays; Izahias, Lívia Maria Santos; Curty, Áquila Almenara; Avelleira, João Carlos Regazzi; Azulay, David Rubem; Pinto, Jony Arrais; Carneiro, Sueli; Dias, Eliane Pedra

doi:10.1111/ijd.13460

Cited by 31 publications

(51 citation statements)

References 39 publications

(70 reference statements)

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“…A few authors have queried whether this could be some local form of psoriasis. An investigation into the molecular mechanism of the disease has revealed that some cases of geographic tongue are caused by a mutation in the interleukin 36 receptor antagonist gene, which is also found in generalized pustular psoriasis . The interleukin 36 receptor antagonist gene encodes the interleukin 36 receptor antagonist, a soluble molecule that counteracts the inflammatory effect of interleukin 36 cytokines by binding their receptor, the interleukin 1 receptor L2, and preventing the downstream activation of nuclear factor kappa‐B signaling .…”

Section: Benign Migratory Glossitismentioning

confidence: 99%

White, red, and mixed lesions of oral mucosa: A clinicopathologic approach to diagnosis

Warnakulasuriya

2019

Periodontology 2000

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A wide range of conditions could present as persistent white or red, or mixed white and red patches on the oral mucosa. Discussed here are some common conditions encountered in clinical practice that appear as white or red patches, together with some rare, but clinically significant, conditions. Based on pathognomonic features, major diagnostic criteria are outlined to help with the differential diagnosis, while some require further investigation (eg, biopsy and/or microbiologic or hematologic investigation) to confirm the provisional clinical diagnosis. Two conditions that require special consideration are leukoplakia and erythroplakia, as they have the potential to transform to cancer.

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Section: Benign Migratory Glossitismentioning

confidence: 99%

White, red, and mixed lesions of oral mucosa: A clinicopathologic approach to diagnosis

Warnakulasuriya

2019

Periodontology 2000

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“…Most cases reported in the literature showed that concomitant tongue involvement, in the form of conventional geographic tongue, is very common (2,7). In contrast to GS, geographic tongue is very common and is characterized by the isolated tongue involvement (8). Patients affected by geographic tongue can be also affected by fissured tongue (3,8,9).…”

Section: Discussionmentioning

confidence: 99%

Geographic stomatitis: An enigmatic condition with multiple clinical presentations

Netto¹,

Dias²,

Garcia³

et al. 2019

J Clin Exp Dent

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Geographic stomatitis is an uncommon inflammatory condition of unknown etiology. It is characterized by reddish areas surrounded by white borders affecting any location in the oral cavity and presenting a migratory and cyclic pattern. The most common affected sites include buccal mucosa, labial mucosa and mucobuccal fold. Some patients can complain of pain or burning sensation. There are few reports in the literature about this entity and its relationship with other oral and cutaneous conditions such as fissured tongue, Reiter’s syndrome, atopy and psoriasis has been suggested but it is still controversial. In the present study we describe three cases of geographic stomatitis associated with fissured tongue. Lesions involved the buccal mucosa, labial mucosa, soft palate and mucobuccal fold and all cases were diagnosed based on their clinical features. All patients were oriented about the innocuous behavior of the condition and were advised to avoid exposure of the lesions to irritation factors. The three presented cases highlighted the importance of a detailed oral mucosal examination by clinicians and provided further information about the natural history and clinical presentation of geographic stomatitis. Key words:Geographic stomatitis, geographic mucositis, geographic tongue.

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“…Given that the etiology GT and FT is unknown, many authors tried to connect it with some systematic conditions and disease, as diabetes mellitus 7 , anemia, allergy 8,9 , celiac disease 10 , anxiety and emotional stress 11 etc. Although GT has been even defined as oral psoriasis 12 , lately some authors found difference in clinical appearance between GT at psoriatic and nonpsoriatic subjects 13 .…”

Section: Sample Collection and Cultivationmentioning

confidence: 99%

Geographic tongue: Does Candida play a role in its pathogenesis

Petrović¹,

Đorđević²,

Radunović³

et al. 2019

Balkan J Dent Med

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Background/Aim: Geographic tongue (GT), a benign self-limiting condition (inflammation) is commonly seen in practice. Although quite easy for clinical diagnosis, in clinical practice it is commonly misdiagnosed and treated as Candida infection. The main aim of this study was to compare the prevalence of Candida spp. on tongue in patients with GT and subjects with clinically healthy oral mucosa. Additional aims were to evaluate subjective symptoms, uncontrolled usage of prescribed or non-prescribed antifungal topical medications and the presence of the cancerophobia or other health concerns in patients with GT. Material and Methods: A total of 70 subjects were divided into two groups: Group B-patients with diagnosed Geographic tongue and group A -aged and gender matched controls with clinically health oral mucosa. Anamnestic charts designed for this study included information about symptoms (measured by Visual Analogue Scale), previous knowledge or fear about presence of GT and received therapy for this condition. Detection of Candida spp. from tongue was done using sterile cotton swab and Sabouraud dextrose agar. Results: At the time of this study, 18 (52.94%) of subjects with GT were aware of having this condition and even 12 of them (66.7%) used topical antifungal drugs prescribed by physician. Also, 66.7% of them experienced fear about the presence of GT at some moment. Detection of Candida spp. was similarly distributed in both groups (22.2% in group A and 17.6% in group B). Conclusions: Geographic tongue has frequently been treated by topical antifungal drugs. In this study, GT was not associated with presence of Candida spp.

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Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis

Cited by 31 publications

References 39 publications

White, red, and mixed lesions of oral mucosa: A clinicopathologic approach to diagnosis

White, red, and mixed lesions of oral mucosa: A clinicopathologic approach to diagnosis

Geographic stomatitis: An enigmatic condition with multiple clinical presentations

Geographic tongue: Does Candida play a role in its pathogenesis

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