A pixel ionization chamber used as beam monitor at the Institut Curie—Centre de Protontherapie de Orsay (CPO)

Rosa, A. La; Garella, Ma; Bourhaleb, F.; Cirio, R.; Donetti, M.; Giordanengo, S.; Givehchi, N.; Marchetto, F.; Martin, F.D.; Meyroneinc, S.; Peroni, C.; Pitta, G.

doi:10.1016/j.nima.2006.06.024

Cited by 30 publications

(13 citation statements)

References 6 publications

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“…The size of these detectors is 24 × 24 cm 2 , to cover the maximum beam size. The detector front-end readout is based on custom designed boards, which host application specific integrated circuit (ASIC) electronics custom designed for this purpose [15,16]. The readout frequency for the integral chamber is about 1 MHz, while for the strip chambers 20 and 10 kHz respectively for x and y strips.…”

Section: Detectors For Beam Control 21 Ionization Chambersmentioning

confidence: 99%

Control Of The Dose Distribution In Charged Particle Therapy

Manganaro¹,

Attili²,

Dalmasso³

et al. 2017

Proceedings of the 26th International Nuclear Physics Conference — PoS(INPC2016)

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The use of ions in radiation therapy aims at improving the selectivity of the irradiation thanks to a favourable depth-dose profile and, in case of heavy ions, to their enhanced radiobiological effect. The treatment modality employing actively scanned pencil beams provides highly conformal dose distributions but is sensitive to uncertainties in the dose calculation, delivery and measurement. During the treatment, the delivery of the beam has to be controlled in real time and monitored with high accuracy, including any effect due to patient positioning and motion. Based on the experience gained in the collaboration with the CNAO (Centro Nazionale di Adroterapia Oncologica, Pavia, Italy), this paper is intended to give an overview of recent techniques and trends for the delivery, measurement and verification of the dose distribution in charged particle therapy with scanned ion beams, focusing in particular on real time and online techniques.

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Section: Detectors For Beam Control 21 Ionization Chambersmentioning

confidence: 99%

Control Of The Dose Distribution In Charged Particle Therapy

Manganaro¹,

Attili²,

Dalmasso³

et al. 2017

Proceedings of the 26th International Nuclear Physics Conference — PoS(INPC2016)

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“…Their design is similar to other detectors successfully developed by the Torino group for different medical applications [5,6]. For safety and redundancy requirements, two independent detectors have been designed for each treatment line: they are housed in separate boxes (called BOX1 and BOX2) and are read out and processed independently during the treatment.…”

Section: Detector Descriptionmentioning

confidence: 99%

“…As described in [5], the electrodes are stretched and glued on fiberglass frames which also provide mechanical support for the front-end readout boards. Additional frames are added between the electrodes to provide a gas gap of 5 mm for each chamber.…”

Section: Detector Descriptionmentioning

confidence: 99%

Design and characterization of the beam monitor detectors of the Italian National Center of Oncological Hadron-therapy (CNAO)

Giordanengo

Donetti

Garella

et al. 2013

Nuclear Instruments and Methods in Physics Research Section A:

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A new hadron-therapy facility implementing an active beam scanning technique has been developed at the italian National Center of Oncological Hadron-therapy (CNAO). This paper presents the design and the characterization of the beam monitor detectors developed for the online monitoring and control of the dose delivered during a treatment at CNAO. The detectors are based on five parallel-plate transmission ionization chambers with either a single large electrode or electrodes segmented in 128 strips (strip chambers) and 32x32 pixels (pixel chamber). The detectors are arranged in two independent boxes with an active area larger than 200 x 200 mm 2 and a total water equivalent thickness along the beam path of about 0.9 mm. A custom front-end chip with 64 channels converts the integrated ionization channels without dead-time. The detectors were tested at the clinical proton beam facility of the Paul Scherrer Institut (PSI) which implements a spot scanning technique, each spot being characterized by a predefined number of protons delivered with a pencil beam in a specified point of the irradiation field. The short-term instability was measured by delivering several identical spots in a time interval of few tenths of seconds and is found to be lower than 0.3%. The non-uniformity, measured by delivering sequences of spots in different points of the detector surface, results to be lower than 1% in the single electrode chambers and lower than 1.5% in the strip and pixel chambers, reducing to less than 0.5% and 1% respectively in the restricted 100 x 100 mm 2 central area of the detector.

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“…Most of the beam monitor detectors are based on ionization chambers [6,7] that offer several advantages in terms of simplicity, robustness and minimal perturbation of the beam. In the perspective of these emerging technologies, the chamber efficiency has to be monitored and eventually corrected for.…”

Section: Introductionmentioning

confidence: 99%

“…In this paper we present a simple and effective solution to increase by almost two orders of magnitude the input current range of an Application Specific Integrated Circuit (ASIC) which was designed by our group and used in several laboratories worldwide [6][7][8], still maintaining a good performance in terms of noise and resolution. The chip, named TERA, implements an architecture based on a charge-to-count converter and integrates 64 equal channels.…”

Section: Introductionmentioning

confidence: 99%

A simple method to increase the current range of the TERA chip in charged particle therapy applications

Cirio

Fausti

Guarachi

et al. 2015

Nuclear Instruments and Methods in Physics Research Section A:

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a b s t r a c tThe development of the next generation of accelerators for charged particle radiotherapy aims to reduce dimensions and operational complexity of the machines by engineering pulsed beams accelerators. The drawback is the increased difficulty to monitor the beam delivery. Within each pulse, instantaneous currents larger by two to three orders of magnitude than present applications are expected, which would saturate the readout of the monitor chambers. In this paper, we report of a simple method to increase by almost two orders of magnitude the current range of an Application Specific Integrated Circuit chip previously developed by our group to read out monitor ionization chambers.

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A pixel ionization chamber used as beam monitor at the Institut Curie—Centre de Protontherapie de Orsay (CPO)

Cited by 30 publications

References 6 publications

Control Of The Dose Distribution In Charged Particle Therapy

Control Of The Dose Distribution In Charged Particle Therapy

Design and characterization of the beam monitor detectors of the Italian National Center of Oncological Hadron-therapy (CNAO)

A simple method to increase the current range of the TERA chip in charged particle therapy applications

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