A peptide aptamer based electrochemical amperometric sensor for sensitive L-glutamate detection

Wang, Wenjing; He, Yumin; Gao, Yunling; Gao, Hongrui; Deng, Lei; Gui, Qingwen; Cao, Zhong; Yin, Yan; Feng, Zemeng

doi:10.1016/j.bioelechem.2022.108165

Cited by 11 publications

(6 citation statements)

References 49 publications

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“…They are a well-known group of sensing methods because the techniques and equipment needed are straightforward. To date, various electrochemical systems for a wide range of analytes, including hormones, viruses, disease indicator biomarkers, and metabolites, have been reported [ 61 , 62 ]. With the help of smartphones, electrochemical sensors are becoming practical biomedical testing tools.…”

Section: Smartphone-based Sensing Methodsmentioning

confidence: 99%

Smartphone-Based Multiplexed Biosensing Tools for Health Monitoring

et al. 2022

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Many emerging technologies have the potential to improve health care by providing more personalized approaches or early diagnostic methods. In this review, we cover smartphone-based multiplexed sensors as affordable and portable sensing platforms for point-of-care devices. Multiplexing has been gaining attention recently for clinical diagnosis considering certain diseases require analysis of complex biological networks instead of single-marker analysis. Smartphones offer tremendous possibilities for on-site detection analysis due to their portability, high accessibility, fast sample processing, and robust imaging capabilities. Straightforward digital analysis and convenient user interfaces support networked health care systems and individualized health monitoring. Detailed biomarker profiling provides fast and accurate analysis for disease diagnosis for limited sample volume collection. Here, multiplexed smartphone-based assays with optical and electrochemical components are covered. Possible wireless or wired communication actuators and portable and wearable sensing integration for various sensing applications are discussed. The crucial features and the weaknesses of these devices are critically evaluated.

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Section: Smartphone-based Sensing Methodsmentioning

confidence: 99%

Smartphone-Based Multiplexed Biosensing Tools for Health Monitoring

et al. 2022

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“…It is essential to adopt a new strategy to fabricate enzyme-free sensors while not reducing the selectivity. 39–41…”

Section: Introductionmentioning

confidence: 99%

“…It is essential to adopt a new strategy to fabricate enzymefree sensors while not reducing the selectivity. [39][40][41] Molecularly imprinted polymers (MIPs) 42 are dense and rigid crosslinked products from crosslinkers and prepolymerization complexes between functional monomers and template molecules. 43,44 Aer the removal of template molecules subsequently, well-dened binding sites are revealed, whereas the arrangement of functional groups is particularly suited for binding the template molecule or to a minor extent structurally related molecules.…”

Section: Introductionmentioning

confidence: 99%

Highly sensitive determination of l-glutamic acid in pig serum with an enzyme-free molecularly imprinted polymer on a carbon-nanotube modified electrode

Yu,

He,

Tang

et al. 2023

Anal. Methods

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“…In medicine, the amount of L-glutamate (L-Glu) in the human body is closely related to various neurological disorders, Parkinson's disease, and amyotrophic lateral sclerosis. 17 Because of the complex operation, time requirements, and high cost of traditional methods for the detection of glutamate, researchers are encouraged to seek a simple, rapid, and economic detection method. 18 Recently, due to the convenience and economy of fluorescence recognition, researchers generally believe that CPs have the potential prospect for fluorescence recognition.…”

Section: Introductionmentioning

confidence: 99%

“…In medicine, the amount of l -glutamate ( l -Glu) in the human body is closely related to various neurological disorders, Parkinson’s disease, and amyotrophic lateral sclerosis . Because of the complex operation, time requirements, and high cost of traditional methods for the detection of glutamate, researchers are encouraged to seek a simple, rapid, and economic detection method .…”

Section: Introductionmentioning

confidence: 99%

Bifunctional Zn Coordination Polymers for High-Performance Fluorescence Turn-On Detection of l-Glutamate and Adsorption of Malachite Green in Aqueous Medium

Gao

Zhang

2023

Crystal Growth & Design

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Two time-induced Zn(II) coordination polymers (CPs), namely {[Zn(BIPA-TC)0.5(1,3-bimb)]·0.75DMF} n (1) and {[Zn(BIPA-TC)0.5(1,3-bimb)]·0.5EtOH·DMF·H2O} n (2) were constructed based on 5,5′-(1,3,6,8-tetraoxybenzo[3,8]phenanthroline 2–7-substituent) bis-1,3-benzoic acid (H4BIPA-TC) and zinc salts. The structure analysis showed that 1 is 3D networks with the point symbol {62, 84} {64, 82}2 and 2 is 2D layered structures with the point symbol of {4, 64, 8}2 {42, 64}. Interestingly, the transformation from single crystal 1 to 2 is only due to the prolongation of reaction time, which can be confirmed by structural analysis and powder X-ray diffraction patterns. Meanwhile, the fluorescence sensing properties of 1 and 2 showed that both 1 and 2 had high sensitivity for l-glutamate with limits of detection of 0.10 (1) and 0.13 μM (2). The fluorescence mechanism analysis showed that the fluorescence enhancement of 1 and 2 is attributed to absorbance caused enhancement and photoinduced electron transfer. In addition, 1 and 2 can also be used as recyclable adsorbents to remove malachite green (MG) in aqueous medium. The adsorption isotherms and kinetics of both 1 and 2 follow the Freundlich model and the quasi-second-order kinetic model, respectively. The maximum equilibrium adsorption capacities of 1 and 2 for MG can reach 351.06 and 250.45 mg/g, respectively. The excellent adsorption properties of 1/2 for MG can be attributed to π–π interaction, hydrogen bonding, and electrostatic interaction between 1/2 and the MG molecule. Therefore, 1 and 2 have potential application prospects in fluorescence recognition and adsorption.

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A peptide aptamer based electrochemical amperometric sensor for sensitive L-glutamate detection

Cited by 11 publications

References 49 publications

Smartphone-Based Multiplexed Biosensing Tools for Health Monitoring

Smartphone-Based Multiplexed Biosensing Tools for Health Monitoring

Highly sensitive determination of l-glutamic acid in pig serum with an enzyme-free molecularly imprinted polymer on a carbon-nanotube modified electrode

Bifunctional Zn Coordination Polymers for High-Performance Fluorescence Turn-On Detection of l-Glutamate and Adsorption of Malachite Green in Aqueous Medium

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