A novel SPR sensor sensitivity-enhancing method for immunoassay by inserting MoS2 nanosheets between metal film and fiber

Song, Hang; Wang, Qi; Zhao, Wan‐Ming

doi:10.1016/j.optlaseng.2020.106135

Cited by 68 publications

(30 citation statements)

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“…Nanomaterial enhancement For OFOF SPR sensors. [101,160,266,283] nanomaterial enhancement has become an effective tool for the detection of low-concentration analytes. For OFOF SPR sensors, many methods to enhance sensitivity have been reported by researchers.…”

Section: Figure 41mentioning

confidence: 99%

“…This means of enhancing the sensitivity has been proved in microfiber modal interferometer, [229] Sagnac interferometer based on elliptic microfiber, [98,232] and microfiber coupler. [247] Fourth, by using some porous, large surface area materials such as, 2D graphene, [101,102] 3D metal oxide, and other nanomaterials, [160,283] the sensitivity of the sensor can be greatly enhanced. Finally, optimizing the spatial distribution of biological receptors to ensure that they can bind more target molecules is also an effective way to improve the sensitivity of the sensors.…”

Section: Sensitivitymentioning

confidence: 99%

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Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Zhang

Zhou

et al. 2021

Laser & Photonics Reviews

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Optofluidic, as an emerging technology that combines photons and microfluidics, has become a powerful, intelligent, and universal sensing platform in the field of bio-chemical sensing. Optical fiber optofluidic (OFOF), as a branch of optofluidic technology, has stimulated a host of remarkable achievements in the field of bio-chemical sensing due to its superiority of compact structure, immunity to electromagnetic interference, low sample consumption, high sensitivity, and real-time dynamic response. In this paper, an overview of OFOF bio-chemical sensors is presented. The OFOF system architectures are introduced and some advanced functional materials and coating technologies that can be utilized in the OFOF sensing platform to achieve high-performance biochemical sensing are summarized. Research progress and current status of OFOF bio-chemical sensors based on various sensing mechanisms are summarized and analyzed, with emphases on their sensing principles, sensing structures, sensing applications, advantages, and disadvantages. Lastly, the existing challenges and future development trends of OFOF biochemical sensors are briefly discussed.

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Section: Figure 41mentioning

confidence: 99%

Section: Sensitivitymentioning

confidence: 99%

Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Zhang

Zhou

et al. 2021

Laser & Photonics Reviews

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“…Examples of BOFS for pH and oxygen detection can be found in Section 3.2.1 and Section 3.2.2 , respectively, whereas those for cancer detection and diagnosis are presented in Section 3.2.3 . In addition, the detection of other diverse biochemical parameters has been recently reported and will be detailed in Section 3.2.4 [ 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 ].…”

Section: Advances In Optical-fibre-based Biomedical Photonic Sensorsmentioning

confidence: 99%

“…To tackle this challenge, a reversible in vivo biosensor based on optical fibres was developed to measure protein carbonylation [ 69 ]. Other recent results are related to SPR optical-fibre sensors for immunoassays, including nanosheets, disposable, and optofluidic systems (for p53 protein) [ 70 , 71 , 72 ].…”

Section: Advances In Optical-fibre-based Biomedical Photonic Sensorsmentioning

confidence: 99%

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Ochoa

Algorri

Roldán-Varona

et al. 2021

Sensors

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In this invited review, we provide an overview of the recent advances in biomedical photonic sensors within the last five years. This review is focused on works using optical-fibre technology, employing diverse optical fibres, sensing techniques, and configurations applied in several medical fields. We identified technical innovations and advancements with increased implementations of optical-fibre sensors, multiparameter sensors, and control systems in real applications. Examples of outstanding optical-fibre sensor performances for physical and biochemical parameters are covered, including diverse sensing strategies and fibre-optical probes for integration into medical instruments such as catheters, needles, or endoscopes.

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“…There are several methods to fabricate the fiber-optic FPI sensor, such as coating film [7], chemical etching [8], laser micromachining [9] and lateral offset splicing [10]. Thus, many fiber-optic FPI sensors have been proposed for temperature monitoring [11], [12], humidity monitoring [13], strain detection [14] gas detection [15], [16], and refractive index (RI) measurement [17], [18].…”

Section: Introductionmentioning

confidence: 99%

All-Fiber Fabry-Perot Interferometer Gas Refractive Index Sensor Based on Hole-Assisted One-Core Fiber and Vernier Effect

Pan

Yang

et al. 2021

IEEE Sensors J.

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A novel high sensitivity all-fiber Fabry-Perot interferometer (FPI) gas refractive index (RI) sensor based on hole-assisted one-core fiber (HAOCF) and Vernier effect was proposed and demonstrated. The sensor is fabricated by splicing a section of HAOCF to a section of silica tube (ST) fused with the lead-in single-mode fiber (SMF), ensuring that the sensor is composed of an air-cavity FPI and a silica-cavity FPI. The cascaded dual-cavities generate the Vernier effect due to a similar free spectrum range (FSR), which significantly improve the sensitivity of the sensor. Owing to the air hole in the cladding of the HAOCF, gases with different RI can enter or leave the in-fiber air cavity, which makes the device usable as a gas RI sensor. The sensor was used to monitor the RI changes of air with different pressures and provided a high sensitivity of −9462.4 nm/RIU. The proposed sensor has a potential to find further applications in the fields of gas composition detection, medical diagnostics and environmental monitoring.

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A novel SPR sensor sensitivity-enhancing method for immunoassay by inserting MoS2 nanosheets between metal film and fiber

Cited by 68 publications

References 1 publication

Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

All-Fiber Fabry-Perot Interferometer Gas Refractive Index Sensor Based on Hole-Assisted One-Core Fiber and Vernier Effect

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