A novel optical approach for determination of prolactin based on Pr-MOF nanofibers

A novel biosensor for early diagnosis of liver cancer cases using smart nano‐magnetic metal–organic framework

“…where F 0 and F are the PL intensities of Cu‐MOF‐NPs in the absence and presence of AFP (quencher), respectively, [Q] is the concentration of AFP and K sv is the Stern–Völmer constant and calculated from the slope of the linear regression of a plot of F 0 / F against [Q]. The limit of detection (LOD) and limit of quantitation (LOQ) were calculated from the formulae LOD = 3.3SD/ b and LOQ = 10SD/ b , where SD is the standard deviation of blank PL intensity values and b is the slope of the linear calibration curve . Moreover, the Stern–Völmer graphs also were obtained at four different temperatures (298, 300, 303 and 310 K).…”

“…The synthetic and design strategies of MOFs as well as their applications depend on the choice of metals, ligands, various organic linkers, solvent used and preparation method . MOFs have many fascinating properties like miscellaneous skeletal structures, small particle sizes, large surface areas, porosity and propensity for host–guest interactions which make them promising for applications in various fields, like sensing, biosensing, gas separations, catalysis, nanomedicine, drug delivery, biomedical applications, biological activity, and several more. Recently, there have been extraordinary achievements in the disciplines of sensing, drug‐delivery control, nanomedicine and cancer therapy applications based on MOFs …”

A novel cerium(iii)–isatin Schiff base complex: spectrofluorometric and DFT studies and application as a kidney biomarker for ultrasensitive detection of human creatinine

“…In addition, it was established that the slopes (K sv values) of the C1 plots were directly proportional to the temperature (Table S9, ESI †), which proves that the quenching mechanism between C1 and creatinine is dynamic. 43,52 Experimental Materials All solvents and chemicals used in this study are analytical reagent grade and were used as received. Isatin (C 11 H 10 ), 2- amino-3-hydroxypyridin (C 5 H 6 N 2 O) and cerium(III)chloride anhydrous CeCl 3 ; 99.9% were purchased from Sigma-Aldrich.…”

A novel, fast, high sensitivity biosensor for supporting therapeutic decisions and onset actions for chest pain cases

“…18 These monomeric units are formed by a combination of metal ions and linkers (organic ligands) through coordination bonds. 19 MOFs are substances that have a broad variety of physical and chemical properties and have a lot of promising application like; sensing/biosensing ability, catalysis, drug delivery, thin lms, used as composite materials, and more. [20][21][22][23] On the other hand, the linkers (ligands) which are used in MOFs synthesis must have specic functional groups as carboxylate, phosphate, pyridyl, etc.…”