A novel approach in electron beam radiation therapy of lips carcinoma: A Monte Carlo study

Shokrani, Parvaneh; Baradaran‐Ghahfarokhi, Milad; Zadeh, Maryam Khorami

doi:10.1118/1.4795756

Cited by 6 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is estimated that MMS procedures performed in the USA in 2013 will have cost more than US$2 billion. 67 Furthermore, data on 217 patients showed that the addition of local adjuvant radiotherapy improved 5-year relapse-free survival from 51% after surgery alone to 92% after adjuvant radiotherapy. Several case series suggest that well-differentiated, slowgrowing tumors of <1.0 cm in diameter can be removed by electrodessication and curettage (ED&C).…”

Section: Treatment Modalitiesmentioning

confidence: 99%

“…66 Another group utilized 6-MeV and 8-MeV electron beam radiotherapy (EBRT) for SCC of the lip and achieved their best outcomes in patients with lesions of 1.5 cm in diameter. 67 Furthermore, data on 217 patients showed that the addition of local adjuvant radiotherapy improved 5-year relapse-free survival from 51% after surgery alone to 92% after adjuvant radiotherapy. 68 The total radiotherapy dose used in SCC of the subungual region is approximately 62 Gy over six weeks; this dose results in no recurrence.…”

Section: Treatment Modalitiesmentioning

confidence: 99%

See 1 more Smart Citation

Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends

2014

View full text Add to dashboard Cite

Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer. It originates from epidermal keratinocytes or adnexal structures (such as eccrine glands or pilosebaceous units). We describe the salient features of cutaneous SCC. We also review novel classification schemes proposed during the last decade which attempt to stratify SCC lesions based on prognosis. Biopsy leads to definitive diagnosis. Treatment includes surgical excision; Mohs micrographic surgery produces excellent cure rates and spares the maximal amount of tissue. Other modalities include electrodessication and curettage, cryosurgery, radiotherapy, topical medications, photodynamic therapy, and systemic therapy. Management and follow-up depend on the risk stratification of individual lesions.

show abstract

Section: Treatment Modalitiesmentioning

confidence: 99%

Section: Treatment Modalitiesmentioning

confidence: 99%

Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends

2014

View full text Add to dashboard Cite

show abstract

“…Lesions may be found early, and so treatment involving surgery and radiotherapy is effective. For radiotherapy, electron beam therapy and brachytherapy are used because the radiation field is limited and located superficially . In 326 lip SCC patients, lymph node metastasis was found in 26 (8%), suggesting that the frequency of cervical lymph node involvement is relatively low.…”

Section: Current Treatment Of Oral Cancermentioning

confidence: 99%

Current treatment, particle radiotherapy, and boron neutron capture therapy for advanced oral cancer in patients

Yura

Tada

Fujita

et al. 2019

Oral Science International

View full text Add to dashboard Cite

Malignant tumors such as squamous cell carcinoma (SCC), malignant salivary gland tumor, mucosal melanoma, sarcoma, and lymphoma occur in the oral cavity. Among them, oral SCC accounts for 90%. The frequency of lymph node metastasis of oral SCC varies depending on the site of occurrence, which affects the prognosis. Surgery is the primary treatment for oral cancer, but when the tumor extends, postoperative radiation with or without chemotherapy is required. Photons including X-rays and γ-rays are the most widely used types of ionizing radiation in cancer radiotherapy. Particle radiotherapy using protons and carbon ions shows a highly focused dose distribution to tumor tissues. Carbon ion therapy is effective for salivary gland tumors, malignant melanomas, and sarcomas which are less susceptible to photons. Furthermore, boron neutron capture therapy with tumor selectivity is expected to further reduce damage to surrounding normal cells. The introduction of novel radiotherapy to current treatment might improve the prognosis of patients and organ preservation. K E Y W O R D S chemotherapy, oral cancer, particle radiotherapy, radiotherapy, surgery How to cite this article: Yura Y, Tada S, Fujita Y, Hamada M. Current treatment, particle radiotherapy, and boron neutron capture therapy for advanced oral cancer in patients. Oral Sci Int. 2019;16:49-68. https://doi.

show abstract

“…This dose enhancement is caused by electron backscattering from the interface. Many studies have measured or calculated the dose enhancement using Monte Carlo simulation (10)(11)(12)(13)(14)(15).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Putty Metal for Internal Shielding for Patient Protection in Electron Therapy by Monte Carlo Study

Birgani¹,

Zabihzadeh²,

Aliakbari³

et al. 2019

Jundishapur J Nat Pharm Prod

View full text Add to dashboard Cite

Background: Lead has been widely used for internal shielding. It is recognized as a toxic material that pollutes the environment and does not fit well the patient's body because of its inflexibility. Objectives: In this study, a specific combination (70% W, 18.61% Ni, and 11.39% C) of lead-free and flexible putty metal was introduced and validated for internal shielding by Monte Carlo study. Methods: To evaluate the putty metal for internal shielding by Monte Carlo study, Varian 2100 C/D was validated within measurements. Then, using the given energy spectrum of Varian 2100 C/D, the shield thickness and backscatter factors were calculated by Monte Carlo study and compared with those of lead. Results: The results showed that this putty metal shield required a comparable thickness compared to lead for providing protection. In addition, it is nontoxic and flexible and can be easily cut. Internal shielding with high atomic number materials causes dose enhancement that is not taken into account in treatment planning systems. This study showed that this composition as an internal shield causes 5%-7% reduction in electron backscatter factor compared to lead. Conclusions: It can be concluded that lead can be replaced by putty metal with a specific combination (70% W, 18.61% Ni, and 11.39% C). It is lead-free and flexible and its required thickness for protection is acceptable under clinical condition. It causes a 5%-7% reduction in electron backscattering.

show abstract

A novel approach in electron beam radiation therapy of lips carcinoma: A Monte Carlo study

Cited by 6 publications

References 24 publications

Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends

Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends

Current treatment, particle radiotherapy, and boron neutron capture therapy for advanced oral cancer in patients

Evaluation of Putty Metal for Internal Shielding for Patient Protection in Electron Therapy by Monte Carlo Study

Contact Info

Product

Resources

About