A Non-surgical lifeline for Abnormal uterine bleeding (AUB)-the LNG IUS

Seeru, Garg; Shet, Anita

doi:10.5958/2394-2754.2016.00005.9

Cited by 8 publications

(6 citation statements)

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“…In our study, 90% of the patients got relieved of heavy menstrual flow within one month of its use and similar trends were noticed by other authors [2,4,5,7,12,15] . (Table No 5).…”

Section: Discussionsupporting

confidence: 91%

“…Decreased blood flow and downregulation of oestrogen receptors in glandular and stromal endometrial tissue leads to atrophy and shrinkage of adenomyosis foci in the myometrium. This allows myometrium to contract better and decreases blood loss and the size of the uterus [2,5,7,17] . Endometrial hyperplasia may be simple or complex, with or without atypia, is another indication where LNG-IUS is being used with 100% response rate.…”

Section: Discussionmentioning

confidence: 99%

“…LNG has been explored for its non-contraceptive benefits by various researchers and found to be effective for women and adolescents as first line therapy with heavy menstrual bleeding and is associated with improved dysmenorrhoea [1] . It was found to be satisfactory, effective and economical alternative to medical surgical treatment of menorrhagia [2,4,5] . Associated medical diseases in which LNG IUS can be used for treatment of HMB are obesity, severe anaemia, coagulopathies where surgery is either contraindicated, is high risk or is not affordable because of high cost [5,6,7,8] .…”

Section: Introductionmentioning

confidence: 99%

“…It was found to be satisfactory, effective and economical alternative to medical surgical treatment of menorrhagia [2,4,5] . Associated medical diseases in which LNG IUS can be used for treatment of HMB are obesity, severe anaemia, coagulopathies where surgery is either contraindicated, is high risk or is not affordable because of high cost [5,6,7,8] . LNG has been associated with irregular spotting for up to 6weeks after insertion and is associated with progressive amenorrhoea [11][12][13][14][15] .…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of non-contraceptive benefits of LNG-IUS: A clinical study

Anju¹,

Kaur²,

Gupta³

2022

Int. J. Clin. Obstet. Gynaecol.

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Introduction: IUCDs are the most widely used and effective contraceptive methods and are safe. Huge variety of IUCDs are available which include inert, copper containing, and medicated with levonorgestrel or indomethacin. LNG has been explored for its non-contraceptive benefits by various researchers and found to be effective for women and adolescents as first line therapy with heavy menstrual bleeding and is associated with improved dysmenorrhoea.so we did a two year perspective study in deptt of obs and gynae at GMC Patiala to assess the role of LNG-IUS IN various gynaecological indication otherthan contraception. Material and Methods: Women with heavy menstrual period, dysmenorrhea or both who reported in the OPD were examined, including breast and pelvic examination. USG was done to note various pathologies like fibroid, endometriosis, endometrial hyperplasia, adenomyosis and functional ovarian cyst. This was followed by endometrial biopsy. After the biopsy report was available, decision for LNG-IUS insertion was taken. LNG-IUS was inserted, under all sterile conditions without anaesthesia. After insertion, patient was followed up at 1-, 3-, 6-and 12-month interval for menstrual pattern change any complications compliance on part of patient. Results: A total of 30 patients were enrolled over a period of two years. 28 patients were in the age group 30-50 years and only 2 patients were post-menopausal. 56.6% had rural background, 43% were illiterate and 83.3% were multipara. In 50% of the women, the chief complaint was heavy menstrual bleeding with dysmenorrhea and 36% had heavy menstrual bleeding alone. 6.6% had dysmenorrhea alone and another 10% reported with irregular bleeding. According to PALM-COIEN classification, AUB-A was diagnosed in 16.6%, AUB-L in 30%, AUB-O in 40%, AUB-M in 3.3%, endometriosis in 13.3%. LNG-IUS was not used as contraception or HRT in any of the cases. On post insertion follow up after one month, 90 percent had relief from heavy menstrual bleeding. At sixmonth follow-up, 23.3% reported spotting and 60% reported normal flow during periods. After one year 73.9% patient had normal flow and 13% patients achieved amenorrhoea. The irregular bleeding or spotting was managed by giving supportive therapy in form of reassurance in 30%, NSAIDS in 16.6%, and norethisterone in 46.6%. Ormeloxifene and OCPs were given in 3.3% each and response was satisfactory. At one year follow up it was seen that 76.6% patients continued with LNG IUS and found it comfortable with enhanced quality of life. Conclusion: LNG-IUS is a better choice for the management of endometrial hyperplasia simple or complex, with or without atypia, AUB, adenomyosis and endometriosis. LNG-IUS can be a good alternative to hysterectomy.

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“…In our study, 90% of the patients got relieved of heavy menstrual flow within one month of its use and similar trends were noticed by other authors [2,4,5,7,12,15] . (Table No 5).…”

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of non-contraceptive benefits of LNG-IUS: A clinical study

Anju¹,

Kaur²,

Gupta³

2022

Int. J. Clin. Obstet. Gynaecol.

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“…Second limitation is that patient was followed up during only one year and further Analysis are required. [6][7][8][9][10] Roy k, 10 conducted a prospective interventional comparative study conducted on women with abnormal uterine bleeding, found statistical improvement in the Hblevel after insertion of LNG-IUS. [11][12][13][14] A observational study conducted by Tariq N to find out clinical response, side effects, and patients acceptability of levonorgestrel -releasing intrauterine system (LNG-IUS).…”

Section: Discussionmentioning

confidence: 99%

The levonorgestrel intrauterine system as an alternative to hysterectomy for treatment of abnormal uterine bleeding

Hosamani¹,

Bidri²

2019

OGIJ

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This study aims to evaluate the hysterectomy cancellation rates after a year of treatment with the levonorgesterol intra uterine system. Materials and methods Method of collection of data\Source of data: This study will include outpatient and inpatient in BLDE University's Shri B. M. Patil Medical College, Hospital & Research Centre who will be diagnosed with abnormal uterine bleeding. The patients will be informed in all respects and informed consent will be obtained.

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Is LNG-IUS the One-Stop Answer to AUB?

Nayar

Nair

George

2017

J Obstet Gynecol India

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A systematic search of the literature available on the use of Levonorgestrel intra-uterine system (LNG-IUS) in women with abnormal uterine bleeding was done. This included PubMed searches up to February 2017 as well as references available with the authors. LNG-IUS usage in other situations was not included in the study. Each relevant published article was evaluated as to whether it served the purpose of this review. Available data show that LNG-IUS is certainly the one-stop answer to AUB, providing a safe and cost-effective treatment and being a substitute for hysterectomy in most women with AUB.

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A Non-surgical lifeline for Abnormal uterine bleeding (AUB)-the LNG IUS

Cited by 8 publications

References 0 publications

Evaluation of non-contraceptive benefits of LNG-IUS: A clinical study

Evaluation of non-contraceptive benefits of LNG-IUS: A clinical study

The levonorgestrel intrauterine system as an alternative to hysterectomy for treatment of abnormal uterine bleeding

Is LNG-IUS the One-Stop Answer to AUB?

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