2007
DOI: 10.1016/j.saa.2006.08.032
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A new spectrophotometric method for the determination of finasteride in tablets

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Cited by 25 publications
(20 citation statements)
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“…Flow injection analysis (FIA) based on natural absorption greatly improves the speed of the analysis but naturally not its selectivity as shown for deflazacort tablets [119]. Spectrophotometrically poorly active steroids such as finasteride in tablets can be determined using colour reactions (in this case the classical extractive colorimetric reaction with bromophenol blue or related dyes) [120]. Of course the selectivity and stability indicating nature of these methods are not any better than those based on natural absorption.…”
Section: Other Methodsmentioning
confidence: 99%
“…Flow injection analysis (FIA) based on natural absorption greatly improves the speed of the analysis but naturally not its selectivity as shown for deflazacort tablets [119]. Spectrophotometrically poorly active steroids such as finasteride in tablets can be determined using colour reactions (in this case the classical extractive colorimetric reaction with bromophenol blue or related dyes) [120]. Of course the selectivity and stability indicating nature of these methods are not any better than those based on natural absorption.…”
Section: Other Methodsmentioning
confidence: 99%
“…Ion-pair complex between cationic surfactants and anionic organic moieties is widely described in the literature [56][57][58][59]. Changes in spectral characteristics of the organic moieties in the presence of different amounts of surfactant may be associated with equilibria involving the surfactant monomers, micelles, aggregation of the organic moiety, complex formation between the organic moiety and surfactant, and the incorporation of additive in the micelle [60][61][62].…”
Section: Partition Constant and Gibbs Energy Changesmentioning
confidence: 99%
“…Multiple analytical procedures have been reported for the analysis of FNS in pharmaceutical preparations when it is present as a single active ingredient or in combination dosage forms, using spectrophotometry (10)(11)(12), thin-layer chromatography (13,14), infrared spectrophotometry (15), polarography (16), voltammetry (17), gas chromatography (18), gas chromatography-mass spectrometry (19), high performance liquid chromatography (HPLC) (20)(21)(22)(23), and ultra-high performance liquid chromatography (UH-PLC) (24,25).…”
Section: Fns Is N-(11-dimethylethyl)-3-oxo-4-aza-5α-androst-1-ene-17mentioning
confidence: 99%