A new regioselective synthesis and bioactivity of 1H‐pyrazolo[3,4‐d]pyrimidin‐4(5H)‐one derivatives

A facile synthesis and fungicidal activities of novel fluorine-containing pyrido[4,3-d]pyrimidin-4(3H)-ones

“…Recently, we have become interested in the synthesis of new bioactive heterocycles such as pyrazolopyrimidinones [13], thienopyrimidinones [14], and triazolopyrimidinones [15] from various iminophosphoranes, with the aim of evaluating their biological activities. Herein, we would like to describe a facile synthesis of 2-substituted-5,8,9-trimethyl-3-(4-fluoro-substituted)phenylthieno[3 0 ,2 0 -5,6]pyrido [4,3-d]pyrimidin-4(3H)-ones (5) via the tandem aza-Wittig and cyclization reaction.…”