A new phenylpropanoid glucoside from the aerial parts ofLygodium japonicum

Abstract

A new compound, 4-O-caffeoyl-D-glucopyranose (1), and a new natural product, 3-O-caffeoyl-D-glucopyranose (2), together with six known compounds (3-8) were isolated from the aerial parts of Lygodium japonicum. Their structures were elucidated on the basis of extensive spectroscopic data analyses. The oxygen radical absorbance capacity assay was applied to evaluate their antioxidative capacities in vitro, which revealed that 1-8 showed strong antioxidative properties.

Lygodium japonicum (Thunb.) Sw

“…Duan et al . () showed that this species has compounds with strong antioxidant properties. Cho et al .…”

“…Formal studies have been conducted to determine the medicinal benefits of L. japonicum. Duan et al (2012) showed that this species has compounds with strong antioxidant properties. Cho et al (2014) found it to be useful as a preventive and therapeutic agent against the formation of oxalate kidney stones, supporting one of the primary traditional uses.…”

Flavonoid Compounds from Krokot Herb (Lygodium microphyllum) and their Antioxidant Activity against DPPH

“…Comparing the NMR data of 6 (Table 2) with the literature data [16], compound 6 was identified as an isorhamnetin-3-O-β-Dglucopyranoside. Antioxidant activity determination of compounds 1-6 was conducted according to the method described in [9] with L-ascorbic acid as positive control. The antioxidant activities of compounds 1-6 are shown in Table 2.…”

“…In our continuing search for novel biologically active compounds from Indonesia Lygodium plants, we isolated two flavonol, quercetin and quercetin-3-O-β-D-glucopyranoside from the ethyl acetate extract of the L. microphyllum herb [9]. In further screening for antioxidant compounds from the L. microphyllum herb we found that the methanol extract showed a significat antioxidant activity against DPPH radical-scavenging.…”

Stigmast-5(6)-en-3(6)-ol dari Herba Tumbuhan Krokot (Lygodium microphyllum)

“…Beberapa tumbuhan Lygodium banyak digunakan oleh masyarakat salah satunya sebagai obat tradisional sebagai obat hepatitis (Zheng dan Xing, 2009), obat sakit pinggang, rematik dan mengatasi batu empedu (Lee et al, 2008), ekspektoran, obat rematik, terkilir, kudis, eksim, dan kelainan hati (Upreti et al, 2009), diuretik, antiplasmodial, rematik, dan pengobatan penyakit paru-paru dan ginjal (Upreti et al, 2009), diuretik, obat pencahar, penghangat tubuh, sakit kepala, kelainan pencernaan dan hepatitis (Zheng dan Xing, 2009), obat pereda sakit saat menstruasi, pencernaan, kontrasepsi, penyembuhan patah tulang, dan pengobatan ambeien (Cambie dan Ash, 1994) dan meredakan batuk (Karthik, 2011). Studi fitokimia pada genus Lygodiumtelah dilaporkan mengandung senyawa dengan struktur yang khas dan aktivitas biologi yang beraneka ragam seperti flavonoid (Zhang et al, 2006), fenolik glikosida (Ye et al, 2007), naftakuinon (Chen et al, 2010), ekdisterosida (Zhu et al, 2009), dan fenil propanoid glikosida (Duan et al, 2012).…”