A new near-infrared ratiometric fluorescent probe for hydrazine

Abstract

It is important to develop fluorescent probes for rapid, selective, and sensitive detection of highly toxic hydrazine in both environmental and biological science. In this text, under mild conditions, a novel nearinfrared (NIR) ratiometric and on-off fluorescent probe 1 was synthesized based on hemicyanine and coumarin derivatives, which can detect hydrazine with high selectivity and anti-interference over other amines, biological species, anions and metal ions. The limit of quantification (LOQ) value was 0-400 mM and the detection limit could be as low as 560 nM.

MB-UiO-66-NH2 Metal-Organic Framework as Chromogenic and Fluorogenic Sensor for Hydrazine Hydrate in Aqueous Solution

“…As a result tedious modifications with the catalyst are required, which increases the complexity and cost. There are also several reports on the sensing of hydrazine using chromogenic and fluorogenic organic chemosensors which act as chemodosimeters and produces ratiometric changes in fluorescence upon the addition of hydrazine . However most chemosensors are either chromogenic or fluorogenic and cannot be applied in pure aqueous systems.…”

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

“…Ni and coworkers reported a hemicyanine and coumarin derivatives based NIR fluorescent on‐off probe 75 for detection of hydrazine (Figure ). This probe itself exhibits two emission peaks centered at 510 nm and 660 nm when excited at 450 nm.…”

Recent progress in the development of fluorescent probes for hydrazine

“…By utilizing 2‐benzothiazoleacetonitrile as a new recognition site, Lin and co‐workers reported a turn‐on two‐photon fluorescent hydrazine probe ( 46 ) . By conjugating hemicyanine to a coumarin fluorophore, Ni and co‐workers developed a NIR‐emissive ( λ ex = 580 nm, λ em = 660 nm) hydrazine selective probe ( 47 ) . Reaction of 47 with hydrazine gives a coumarin hydrazone derivative and a corresponding blue‐shift emission, and thus a ratiometric fluorescence response is achieved.…”