“…m endocrinology, to a decisive improvement of clinical fc to reyew ^ assay ^pj^ precision> accuracy , diagnosis. specificity, detectability and practicability of enzyme In recent years the usefulness of many other markers -immunoassays currently available for routine use in such as enzymes (2-4), a coenzyme (5-6), a fluorogenic clinical chemical laboratories, substrate (7-9)^ fluorescent dyes (10)(11)(12)(13), chemiluminescence producing compounds (14), ä lüminol reactive heme containing compound (15), stable free Assay principles radicals (16), bacteriophages (17) and polystyrene beads . H hap ten, E-H enzyme labeled hap ten, AB limited amount of antibody, i inhibition of the "marker enzyme", S substrate and P product of the enzymic reaction.…”