A new dicyanoisophorone-based ratiometric and colorimetric near-infrared fluorescent probe for specifically detecting hypochlorite and its bioimaging on a model of acute inflammation

Lan, Jin‐Shuai; Guo, Jing; Jiang, Xiaoyi; Chen, Yi; Hu, Zhenghao; Que, Yuan-Fang; Li, Hongxin; Gu, Jing-Yi; Ho, Rodney J. Y.; Zeng, Ruifeng; Ding, Yue; Zhang, Tong

doi:10.1016/j.aca.2019.09.076

Cited by 28 publications

(6 citation statements)

References 36 publications

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“…Zebrafish experiments proved that BK was organism-permeable and can monitor ClO − in living organisms. Importantly, BK is the first fluorescent turn-off sensor capable of sensing ClO − in zebrafish ( Table S1 ) [ 1 , 38 , 54 , 55 , 56 , 57 , 58 , 59 ].…”

Section: Resultsmentioning

confidence: 99%

An Acridine-Based Fluorescent Sensor for Monitoring ClO− in Water Samples and Zebrafish

Lee

Park

et al. 2020

Sensors

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A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO− and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, BK was satisfactorily applied for sensing ClO− in water samples and zebrafish.

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Section: Resultsmentioning

confidence: 99%

An Acridine-Based Fluorescent Sensor for Monitoring ClO− in Water Samples and Zebrafish

Lee

Park

et al. 2020

Sensors

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“…The fabrication of DDPB was improved referring to Ding 30 with the precursor chemical catalyst replaced by common ammonium acetate. Simply, (3,5,5-trimethylcyclohexane-2-enyl)malonitrile (187 mg, 1 mmol) and 4-formylbenzenboric acid (150 mg, 1 mmol) were added into 10 mL of dry ethanol at room temperature.…”

Section: Methodsmentioning

confidence: 99%

A latent reversible ratiometric optical pH sensing probe based on phenylboronic acid for alkaline pH detection and applications in test paper and alkalotic HK-2 cells

Fang,

Xu,

Gong

et al. 2023

New J. Chem.

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“…Endogenous ClO − is helpful for the immune system of organisms. [ 43 ] However, ClO − concentration disorders can cause various diseases, such as lung injury, [ 44 ] cardiovascular diseases, [ 45 ] inflammation, [ 46 ] and cancers. [ 47 ] Pu et al explored an amphiphile SOA‐based nanoprobe for the in vivo visualization of ClO − via ratiometric PA imaging ( Figure a).…”

Section: Stimuli‐responsive Organic Nir Pa Probesmentioning

confidence: 99%

Stimuli‐Responsive Organic Near‐Infrared Photoacoustic Probes

Shen

Wang

Ruan

et al. 2023

Adv Funct Materials

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Photoacoustic (PA) imaging is an emerging biomedical imaging technique with the features of non‐invasiveness and non‐ionization. It takes advantage of the photothermal effect of PA probes to convert absorbed photon energy into heat and subsequent transient thermoelastic tissue expansion for ultrasonic waves for PA images. Thus, PA imaging exhibits the combined superiority of high‐contrast optical imaging and deep tissue penetration of acoustic imaging, which furnishes high‐resolution and high‐contrast tissue images. Stimuli‐responsive organic PA agents in the near‐infrared (NIR) biological window have attracted increasing attention because of their low biological toxicity and response characteristics. This review focuses on the recent research progress of stimuli‐responsive organic NIR probes for PA imaging, including the temperature response, pH response, redox response, metal ion response, and enzyme response. And the stimuli‐responsive mechanisms are highlighted in detail. Moreover, their perspectives and challenges are discussed. It will be of great help for the further development of organic NIR PA probes with stimuli‐response.

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A new dicyanoisophorone-based ratiometric and colorimetric near-infrared fluorescent probe for specifically detecting hypochlorite and its bioimaging on a model of acute inflammation

Cited by 28 publications

References 36 publications

An Acridine-Based Fluorescent Sensor for Monitoring ClO− in Water Samples and Zebrafish

An Acridine-Based Fluorescent Sensor for Monitoring ClO− in Water Samples and Zebrafish

A latent reversible ratiometric optical pH sensing probe based on phenylboronic acid for alkaline pH detection and applications in test paper and alkalotic HK-2 cells

Stimuli‐Responsive Organic Near‐Infrared Photoacoustic Probes

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