A New 675 nm Laser Device in the Treatment of Facial Aging: A Prospective Observational Study

Cannarozzo, Giovanni; Fazia, Gilda; Bennardo, Luigi; Tamburi, Federica; Amoruso, Giuseppe Fabrizio; Duca, Ester Del; Nisticò, Steven Paul

doi:10.1089/photob.2020.4908

Cited by 31 publications

(34 citation statements)

References 15 publications

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“…The macroscopic characteristics of skin photoaging include wrinkle formation, rough texture, pigmentation, and loss of skin elasticity. Histological and ultrastructural studies have shown epidermal hyperplasia, damage, and disorder of collagen fibers, and a large accumulation of abnormal elastic substances in connective tissue in photoaged skin [32,33]. These effects are less pronounced in the epidermis owing to high turnover.…”

Section: Uv-induced Skin Photoagingmentioning

confidence: 99%

Boosting the Photoaged Skin: The Potential Role of Dietary Components

et al. 2021

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Skin photoaging is mainly induced by ultraviolet (UV) irradiation and its manifestations include dry skin, coarse wrinkle, irregular pigmentation, and loss of skin elasticity. Dietary supplementation of nutraceuticals with therapeutic and preventive effects against skin photoaging has recently received increasing attention. This article aims to review the research progress in the cellular and molecular mechanisms of UV-induced skin photoaging. Subsequently, the beneficial effects of dietary components on skin photoaging are discussed. The photoaging process and the underlying mechanisms are complex. Matrix metalloproteinases, transforming growth factors, skin adipose tissue, inflammation, oxidative stress, nuclear and mitochondrial DNA, telomeres, microRNA, advanced glycation end products, the hypothalamic–pituitary–adrenal axis, and transient receptor potential cation channel V are key regulators that drive the photoaging-associated changes in skin. Meanwhile, mounting evidence from animal models and clinical trials suggests that various food-derived components attenuate the development and symptoms of skin photoaging. The major mechanisms of these dietary components to alleviate skin photoaging include the maintenance of skin moisture and extracellular matrix content, regulation of specific signaling pathways involved in the synthesis and degradation of the extracellular matrix, and antioxidant capacity. Taken together, the ingestion of food-derived functional components could be an attractive strategy to prevent skin photoaging damage.

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Section: Uv-induced Skin Photoagingmentioning

confidence: 99%

Boosting the Photoaged Skin: The Potential Role of Dietary Components

et al. 2021

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“…Surgical techniques offer immediate results; however, they are expensive and associated with a risk of pain and swelling [ 5 ]. Various laser and light treatments were also proposed to prevent and treat facial aging and dry skin, with variable results [ 6 , 7 ]. Topical drugs and cosmetic creams are relatively inexpensive treatment options.…”

Section: Introductionmentioning

confidence: 99%

Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study

Hsu

Hsieh

et al. 2021

Nutrients

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Hyaluronan (HA) is present in all connective tissues and organs, including the skin and joint fluid. However, few clinical trials have comprehensively evaluated the impacts of oral HA on skin conditions, including wrinkles and moisturization. In this study, we conducted a placebo-controlled, randomized, double-blind trial of daily HA (120 mg) intake for 12 weeks in 40 healthy Asian men and women (aged 35–64 years). Skin condition was determined by the evaluation of wrinkles, stratum corneum water content, the amount of transepidermal water loss, elasticity, and through image analysis. After 12 weeks, skin condition was significantly improved in terms of wrinkle assessment, stratum corneum water content, transepidermal water loss, and elasticity in the HA group compared to the placebo group. Regarding the percentage change from baseline, wrinkle assessment, stratum corneum water content, and skin elasticity were significantly improved in the HA group versus the placebo group after 8 and 12 weeks of ingestion. The present findings indicate that oral ingestion of HA may suppress wrinkles and improve skin condition.

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“…Despite excellent results, they have been associated with considerable disadvantages such as pain, crusting, swelling, infections due to a prolonged recovery period, long-lasting erythema, and potential complications such as pigmentary changes and scarring [3][4][5]. For several years, researchers have been looking for non-invasive methods that will allow the deposition of thermal energy in the dermis in a way that triggers collagen remodeling and neocollagenesis while sparing the epidermis from injury [6].…”

Section: Introductionmentioning

confidence: 99%

Periocular rejuvenation using a unique non-ablative long-pulse 2940 nm Er:YAG laser

Badawi

Sobeih

Jasmina³

2021

Lasers Med Sci

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The periocular region is challenging for cosmetic laser surgeons. Surgery and laser resurfacing have traditionally been used to correct periorbital lines and wrinkles. Although effective, the associated downtime with these methods has made many people reluctant to decide for such treatments. More recently, the non-ablative long-pulse 2940 nm Er:YAG laser is being used to improve the structure and function and hence the appearance of skin in the periorbital region. The objective of this study is to evaluate the safety and efficacy of long-pulse 2940 nm Er:YAG laser for non-ablative treatment of periorbital static wrinkles and skin laxity. This is a prospective analysis of 30 patients treated for periorbital rejuvenation using three sessions of non-ablative long-pulse Er:YAG laser over a 3-month period. All patients were assessed according to Fitzpatrick’s classification of periorbital wrinkles to class I, II, or III and were treated with 2940 nm Er:YAG laser using a fluence of 3.75 J/cm2, a repetition rate of 1.7–2 Hz, and with the SMOOTH™ pulse mode (250 ms). The treatment sessions were performed on each patient, 4 weeks apart. Patient improvement was assessed before each laser session as well as at 12 months after the final treatment. Blind photographic evaluations were performed by three independent physicians using unlabeled before and after photos arranged in non-chronological order. Reviewers were asked to determine the before and after photos. Patients were asked to answer a questionnaire measuring satisfaction 4 weeks after each session, and to report any adverse reactions. There was statistically and clinically significant improvement in the Fitzpatrick classification of the periorbital wrinkles. Blinded evaluators correctly identified the before and after photos in all cases. All patients reported mild edema and erythema, which persisted for 1 to 2 days, and superficial peeling of the skin for 4 to 6 days after each laser treatment. No long-term adverse effects were reported. The non-ablative long-pulse 2940 nm Er:YAG laser seems to be a safe and effective treatment for periocular rejuvenation with minimal and tolerable adverse reaction. The improvement attained from the laser sessions was persisting after 1 year denoting the long-term efficacy of the procedure.

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A New 675 nm Laser Device in the Treatment of Facial Aging: A Prospective Observational Study

Cited by 31 publications

References 15 publications

Boosting the Photoaged Skin: The Potential Role of Dietary Components

Boosting the Photoaged Skin: The Potential Role of Dietary Components

Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study

Periocular rejuvenation using a unique non-ablative long-pulse 2940 nm Er:YAG laser

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