A nanostructured Fabry-Perot interferometer

Zhang, Tianhua; Gong, Zhongcheng; Giorno, Rebecca; Que, Long

doi:10.1364/oe.18.020282

Cited by 40 publications

(25 citation statements)

References 18 publications

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“…Taiwan Yuan Ze University formed metal bipolar plate by chemical corrosion and simulations for this process were also carried out using the finite element method. Zhang in Louisiana Tech University had made a nanostructured Fabry-Perot interferometer by MEMS technology [8]. Technology for deformed metal bipolar with low cost, high efficiency and mass production were needed in order to meet the demand of market.…”

Section: Introductionmentioning

confidence: 99%

Study of micro electromagnetic bulging on a stainless steel foil

Zhao

Wang

et al. 2015

Manufacturing Rev.

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-Electromagnetic micro-forming is a novel technology of micro-fabrication with high-energy rate which shows superiority in fabricating shallow and concave parts. In the research reported in this paper, micro electromagnetic bulging process was carried out with stainless steel foil, and the effects of discharge parameters and foil thickness on the deformation quality were analyzed. The results show that the surface quality and the forming depth of micro channels could be improved by increasing discharge energy and frequency. The discharge frequency has more effect on the micro electromagnetic forming quality. With the increase of the discharge frequency, the depth of micro channel reaches maximum value firstly and then decreases. The surface quality and depth of micro channel decreases with increase of the foil thickness. Optimum parameters arrays of micro channel with good surface quality and dimensional accuracy were obtained in the electromagnetic micro-forming of a stainless steel foil.

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Section: Introductionmentioning

confidence: 99%

Study of micro electromagnetic bulging on a stainless steel foil

Zhao

Wang

et al. 2015

Manufacturing Rev.

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“…12 One category of the label-free bionanosensors is enabled by the nanopore structures as the thin film reflective interferometric devices. 13 14 Recently the white-light source operated polymer-based Fabry-Perot interferometer (FPI) chips and the polymer-based nanostructured FabryPerot interferometer (FPI) chips have been developed for biodetection, [15][16][17][18][19] offering potentially powerful label-free technical platforms for the detection of protein/cancer biomarkers. For instance, the nanostructured FPI chips have been demonstrated for the detection of prostate cancer biomarkers free prostate-specific antigen (f -PSA) at 140 femtomolar concentration, indicating its great potential for early stage detection of various diseases.…”

Section: Introductionmentioning

confidence: 99%

“…Another very important issue related to current technologies is that both the silicon and AAO nanopore layer for the thin-film devices or the nanopore layer anchored inside the FPI cavity is not optically transparent. [13][14][15][16][17][18] As a result, the transducing signals from these devices or microchips are the reflected interference fringes. While it is not too inconvenient and problematic for measurements on one single device, it is becoming increasingly challenging and difficult for measurements on large-scale arrayed devices, which is the key for achieving the multiplexed detection with high throughput.…”

Section: Introductionmentioning

confidence: 99%

A Transparent Nanostructured Optical Biosensor

He¹,

Li²,

Que³

2014

j biomed nanotechnol

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Herein we report a new transparent nanostructured Fabry-Perot interferometer (FPI) device. The unique features of the nanostructured optical device can be summarized as the following: (i) optically transparent nanostructured optical device; (ii) simple and inexpensive for fabrication; (iii) easy to be fabricated and scaled up as an arrayed format. These features overcome the existing barriers for the current nanopore-based interferometric optical biosensors by measuring the transmitted optical signals rather than the reflected optical signals, thereby facilitating the optical testing significantly for the arrayed biosensors and thus paving the way for their potential for high throughput biodetection applications. The optically transparent nanostructures (i.e., anodic aluminum oxide nanopores) inside the FPI devices are fabricated from 2.2 microm thick lithographically patterned Al thin film on an indium tin oxide (ITO) glass substrate using a two-step anodization process. Utilizing the binding between Protein A and porcine immunoglobulin G (IgG) as a model, the detection of the bioreaction between biomolecules has been demonstrated successfully. Experiments found that the lowest detection concentration of proteins is in the range of picomolar level using current devices, which can be easily tuned into the range of femtomolar level by optimizing the performance of devices.

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“…5 Additionally, the aluminum oxide (AAO) nanopores are fabricated from Al foil thin film (typically 1.0 mm thick, purity 99.998%) using a two-step anodization process. 6,7 Once the nanopore thin film has been fabricated, the drugs can be loaded into the nanopores, followed by depositing a layer of polymer. As a result, the a) Author to whom correspondence should be addressed.…”

Section: Introductionmentioning

confidence: 99%

A microfluidic chip for controlled release of drugs from microcapsules

Cheng

Chang

et al. 2013

Biomicrofluidics

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A new microfluidic device with liquid-droplet merging and droplet storage functions for the controlled release of drugs from microcapsules is reported. A switching channel is designed and integrated within the microfluidic device, facilitating the generation and capturing of uniform droplets by the storage chambers. The drug model is the MnCO 3 microparticle, which is encapsulated by a microcapsule and fabricated using a simple layer-by-layer nanoassembly process. The merging function is used for dynamically adding the control solution into the droplets, which contain drugs within the microcapsules (DWlCs) and water. The storage chambers are used for collecting DWlCs-laden droplets so that the controlled-drug release in specific droplets can be monitored for an extended period of time, which has been experimentally implemented successfully. This technology could offer a promising technical platform for the long-term observation and studies of drug effects on specific cells in a controlled manner, which is especially useful for single cell analysis. V C 2013 AIP Publishing LLC.

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A nanostructured Fabry-Perot interferometer

Cited by 40 publications

References 18 publications

Study of micro electromagnetic bulging on a stainless steel foil

Study of micro electromagnetic bulging on a stainless steel foil

A Transparent Nanostructured Optical Biosensor

A microfluidic chip for controlled release of drugs from microcapsules

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