A mitochondria-targeting ratiometric fluorescent probe for the detection of hypochlorite based on the FRET strategy

Abstract

In this study, a ratiometric fluorescent probe (IRP) for À OCl was designed based on the fluorescence resonance energy transfer (FRET) platform. The probe was fabricated by integrating an imidazo [1,5-a] pyridine moiety (donor) with a rhodamine moiety (acceptor). We evaluated its properties for recognizing

A fluorescence sensing platform of theophylline based on the interaction of RNA aptamer with graphene oxide

“…The result is similar to a previous report. 28 The typical HRTEM image of asprepared GO showed that the GO sheet was about 1 Â 1 mm in size with occasional folds, crinkles and rolled edges (Fig. 1C).…”

Luminescent Imidazo[1,5‐a]pyridine Scaffold: Synthetic Heterocyclization Strategies‐Overview and Promising Applications

“…In general, the donor emission dye must have a strong overlap with the acceptor absorption, which essentially restricts the development of FRET‐based couple systems. To this end, different groups have recently designed and synthesized new impy probes, demonstrating their value for FRET‐based practical applications [11,125,126,131] …”

“…Moreover, hydrogen ion plays an important role in the entire cell life (tumour growth and corresponding enzymatic and metabolic activity proliferation), at this regards impy probes have been reported as “ on‐off ” pH probe in living cells [10,31] . In this context, different groups have recently designed and synthesized new fluorophores based on impy nucleus, demonstrating their value for ratiometric pH‐sensors based on a dual emission pathway [29,30] and FRET‐based practical applications in biological systems [11,125,126,131] …”

“…To this end, different groups have recently designed and synthesized new impy probes, demonstrating their value for FRET-based practical applications. [11,125,126,131] The electroluminescence of impy has been recently investigated by G. Albrecht et al, studying layered OLEDs based on this emissive nucleus. [18,20] up to now only copper complexes bearing impy ligands have been successfully employed in lightemitting electrochemical cells (Figure 3, images collected by the author).…”

“…[10,31] In this context, different groups have recently designed and synthesized new fluorophores based on impy nucleus, demonstrating their value for ratiometric pH-sensors based on a dual emission pathway [29,30] and FRET-based practical applications in biological systems. [11,125,126,131]…”