A method for studying the ultrastructure of intercellular contacts in leukocyte cultures

High-resolution microscopy of the implant-tissue interface

“…For practical purposes, however, the plane of separation obviously does not disturb the fine anatomy of the fibrillar or cellular structure at the interface. Consequently, it would seem that the technique of separating monolayers of cells from culture dishes applies to whole tissue as well (Chang 1971, Elias et al 1971). …”