A meta-analysis of treatments for panic disorder with agoraphobia: Imipramine, alprazolam, and in vivo exposure

Cox, Brian J.; Endler, Norman S.; Lee, Paul S.; Swinson, Richard P.

doi:10.1016/0005-7916(92)90034-g

Cited by 58 publications

(46 citation statements)

References 27 publications

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“…Now, while the relationship of the change in panic and in avoidance is of both theoretical and clinical interest, the pervasiveness of PDA as a clinical disorder is not fully accounted for in this relationship. And, indeed, the successful treatment of agoraphobia has been found associated with altered depression (Chambless, 1985) and general anxiety (Cox, 1992). Findings also indicate that psychological treatment for panic disorder is accompanied by a decline in other comorbid anxiety disorders or mood disorders (Brown, Anthony & Barlow, 1995).…”

Section: Generalization Of Symptomsmentioning

confidence: 94%

“…In vivo exposure has been found to not only address the problem of agoraphobic avoidance, but it has also been found to have a substantial impact on panic frequency, even in the absence of interventions specifically targeting these attacks (Cox et al, 1992;Williams & Falbo, 1996). The literature does seem consistent with a change route where a decrease in panic follows reductions in avoidance.…”

Section: Generalization Of Symptomsmentioning

confidence: 98%

“…The authors argued that their data provided quite strong evidence that the effects on panic were by way of psychological treatments verified. Cox, Endler, Lee and Swinson (1992) conducted a meta-analysis of treatment studies published during the eighties. Studies were included if they focused on panic disorder with/without agoraphobia (or agoraphobia with panic attacks, if DSM-III nomenclature was used), and treatment with alprazolam, imipramine, in vivo exposure, or placebo.…”

Section: Treatment Efficacymentioning

confidence: 99%

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Behavioral Treatments of Panic Disorder with Agoraphobia: Treatment Process and Determinants of Change

Ramnerö¹

2005

PsycEXTRA Dataset

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The present dissertation comprises four empirical studies within the area of behavioral treatment of panic disorder with agoraphobia. The focus is on studying issues pertaining to outcome, treatment process and determinants of change. The first study is a randomized controlled treatment study of 73 patients undergoing 16 sessions of either exposure in vivo (E), or cognitive behavior therapy (CBT). Both treatments showed clear improvements at post-treatment that were well maintained at 1-year follow up, and there were no significant differences between the treatments. The second study concerned prediction of outcome in the same sample. From a variety of pre-treatment characteristics severity of avoidance was the one most related to outcome. Most predictors were found unrelated. Two approaches of prediction were also compared: treating outcome as a categorical vs. continuous variable. The different approaches yielded a somewhat dissimilar picture of the impact of pre-treatment severity of avoidance. The third study examined different aspects of the therapeutic relationship, and their relation to outcome. Clients' perceptions of therapists and their ratings of the working alliance were generally not related to outcome at any point. On the other hand, therapists' perceptions of patients as showing goal-direction and active participation were related to outcome from early on in therapy. The fourth study examined different aspects of change. It was found that change in indices of the frequency of panic attacks was not closely related to change in agoraphobic avoidance at post-treatment. Change in avoidance was also more related to other aspects of outcome. At one-year follow-up, a more unitary picture, regarding the different aspects of change was observed.

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Section: Generalization Of Symptomsmentioning

confidence: 94%

Section: Generalization Of Symptomsmentioning

confidence: 98%

Section: Treatment Efficacymentioning

confidence: 99%

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Behavioral Treatments of Panic Disorder with Agoraphobia: Treatment Process and Determinants of Change

Ramnerö¹

2005

PsycEXTRA Dataset

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“…In een meta-analyse van 34 onderzoeken kon geen significant effect van exposure op paniek worden vastgesteld (Cox et al, 1992). De auteurs schrijven dit echter toe aan factoren die samenhangen met verschillen in de steekproefgrootte van de diverse onderzochte groepen.…”

Section: Effecten Van De Behandeling Van Paniekunclassified

“…In één meta-analyse werd voor deze factor op de Fear Questionnaire (Marks & Mathews, 1979) een effect-grootte van 1.93 gevonden (Ogles et al, 1990), in een andere meta-analyse was dat 3.32 (Cox et al, 1992 …”

Section: Gepercipieerd Agorafobisch Gedragunclassified

Paniekmanagement en exposure in vivo bij paniekstoornis met agorafobie

Korrelboom¹,

Kernkamp²,

Hoogduin³

et al. 1995

DITH

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VTwee mensen wil ik speciaal bedanken. Allereerst Bobby Kernkamp. Zonder hem zou dit proefschrift er nooit zijn gekomen. Het begon als een aardigheidje om, werkend bij verschillende werkgevers, toch te kunnen samenwerken. Bobby, al zo dikwijls gewend om 'groter' te denken dan ik, maakte het tot een wetenschappelijk onderzoek waarop wij gezamenlijk zouden promoveren. Om het project niet uit de hand te laten lopen moesten we besluiten, veel later en in vriendschappelijk overleg, dat het werk gescheiden zou worden voltooid. Het is voor beiden, denk ik, een verstandig besluit geweest. Het project is pas echt afgelopen, wanneer ook zijn dissertatie klaar is.Dan is er mijn Rooie. Onmisbare hulp bij het temmen van mijn PC. Onmisbare steun door aan te moedigen waar dat nodig en te zwijgen waar dat verstandig was. Gezegend met een onganse behoefte aan slaap. Terwijl zij sliep kon ik, zonder al te veel gevoelens van schuld, 's ochtends plaatsnemen achter mijn bureau. In de weekends en op vrije dagen. Onmisbaar vooral als levenspartner en vriendin. Zonder haar zou het zeker uit de hand zijn gelopen. Ik dank haar. Ons leven zal voortaan een beetje anders zijn.

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Fears and phobias in people with diabetes

Green¹,

Feher

Catalán³

2000

Diabetes Metab. Res. Rev.

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Phobic disorders are more common in people with diabetes than in the general population. The management of phobic disorders in patients with diabetes, particularly when associated with a fear of hypoglycaemia, is especially challenging and requires close collaboration between psychological medicine and diabetes teams. Difficulty in distinguishing symptoms of anxiety from those of hypoglycaemia, and the real dangers associated with hypoglycaemia, complicate the delivery of psychological interventions that are used routinely in the treatment of phobias. Avoidance of hypoglycaemia can lead to deterioration in diabetes control. This case report describes a man with Type 1 diabetes who developed agoraphobia with panic disorder, associated with fear of hypoglycaemia and deterioration in glycaemic control. The management of patients with diabetes and phobic disorders, with particular reference to those associated with fear of hypoglycaemia, is discussed.

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A meta-analysis of treatments for panic disorder with agoraphobia: Imipramine, alprazolam, and in vivo exposure

Cited by 58 publications

References 27 publications

Behavioral Treatments of Panic Disorder with Agoraphobia: Treatment Process and Determinants of Change

Behavioral Treatments of Panic Disorder with Agoraphobia: Treatment Process and Determinants of Change

Paniekmanagement en exposure in vivo bij paniekstoornis met agorafobie

Fears and phobias in people with diabetes

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