A mathematical model for agitation-induced fragmentation of

Jüsten, Peter; Paul, Gour Chandra; Nienow, Alvin W.; Thomas, Carelle

doi:10.1007/s004490050404

Cited by 3 publications

(2 citation statements)

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“…4. The results are in the same range as found by Jüsten et al [35]. The difference may be explained in terms of the different stirrer diameter/vessel diameter ratios.…”

Section: Power Numbersupporting

confidence: 86%

Flow Field Analysis of Stirred Liquid‐Liquid Systems in Slim Reactors

Maaß¹,

Eppinger²,

Altwasser³

et al. 2011

Chem Eng & Technol

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Previous studies have shown the great potential, but also the great challenges, in handling slim reactors often used for polymerization reactions. Experiments and simulations were carried out in reactors with aspect-to-diameter ratios of up to 5, to test and to evaluate the mixing and dispersion efficiency for liquid-liquid systems of single-and multiple-stage impellers. Therefore, power consumption, mixing time and minimum dispersion speed were determined for five different stirrer types under turbulent conditions. It was found that the dimensionless mixing time is highly sensitive to the configuration of the impellers, with almost no dependency on the turbulent power number. Another focus was the analysis of the effect of the baffles. The influence of the baffle length in slim reactors on the mixing time and the macroscopic flow field was determined.

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“…4. The results are in the same range as found by Jüsten et al [35]. The difference may be explained in terms of the different stirrer diameter/vessel diameter ratios.…”

Section: Power Numbersupporting

confidence: 86%

Flow Field Analysis of Stirred Liquid‐Liquid Systems in Slim Reactors

Maaß¹,

Eppinger²,

Altwasser³

et al. 2011

Chem Eng & Technol

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“…To quantify morphology, samples were prepared and images of fungal elements were analyzed as described previously (3, 7, 11, 12). Both freely dispersed mycelia and clumps were measured together to determine average projected area (μm 2 ), which is a frequently used measure of fungal element size (13, 14). Comparisons made using analysis of variance, with significance level ( P ) of <0.05 considered indicative of significant difference.…”

Section: Methodsmentioning

confidence: 99%

Pulsed Feeding during Fed-Batch Aspergillus oryzae Fermentation Leads to Improved Oxygen Mass Transfer

2003

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Productivity in many fungal fermentations is detrimentally affected by high broth viscosity and consequent reduced oxygen mass transfer capacity. The goal here was to determine whether pulsed feeding of limiting carbon in a fungal fermentation could lead to reduced viscosity and improved oxygen mass transfer. As a model, an industrially relevant recombinant strain of Aspergillus oryzae was grown in carbon-limited, fed-batch mode. Maltodextrin was used as a carbon source and was added either continuously or in 1.5-min pulses, 3.5 min apart. In both feeding modes the same total amount of carbon was added, and carbon feed rate was at sufficiently low levels to ensure cultures were always carbon-limited. Compared to continuous feeding, pulsed addition of substrate led to smaller fungal elements, which resulted in a significant reduction in broth viscosity. This in turn led to higher dissolved oxygen concentrations and increased oxygen uptake rates during pulsed feeding.

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The Effect of Hydrodynamics on Biological Materials

Thomas

Zhang

1998

Advances in Bioprocess Engineering

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A mathematical model for agitation-induced fragmentation of

Cited by 3 publications

References 0 publications

Flow Field Analysis of Stirred Liquid‐Liquid Systems in Slim Reactors

Flow Field Analysis of Stirred Liquid‐Liquid Systems in Slim Reactors

Pulsed Feeding during Fed-Batch Aspergillus oryzae Fermentation Leads to Improved Oxygen Mass Transfer

The Effect of Hydrodynamics on Biological Materials

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