A longitudinal prospective study of men with mild symptoms of BOO treated with watchfull waiting over 4 years

Integrating risk profiles for disease progression in the treatment choice for patients with lower urinary tract symptoms/benign prostatic hyperplasia: a combined analysis of external evidence and clinical expertise

“…Although symptoms wax and wane in individual patients and some patients may remain stable or improve, the majority of patients experience symptom deterioration over time. 1,2 In addition, LUTS/BPH may lead to the development of serious complications such as acute urinary retention (AUR), which usually necessitates invasive treatment. 3 Over the last few years, the focus in managing LUTS/BPH has therefore been widened from short-term symptom relief to durable efficacy, the prevention of serious complications, and the reduction of the risk of invasive treatment.…”

Management of lower urinary tract symptoms suggestive of benign prostatic hyperplasia: the central role of the patient risk profile

“…In an Austrian study that followed 1208 patients with LUTS/BPH for 4 years of watchful waiting, the percentage of patients whose symptoms worsened from mild to severe increased from 13% at 1 year to 31% at 4 years (Fig. 1) [8]. After 1 year, 20% of the patients reported an improvement in symptoms, but after 4 years only 3% of the patients did.…”