A Long-Term Follow-Up Study of Severe Variant of Central Serous Chorioretinopathy

Otsuka, S; Ohba, Norio; Nakao, Kumiko

doi:10.1097/00006982-200202000-00005

Cited by 79 publications

(86 citation statements)

References 12 publications

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“…While CSC is usually associated with small to moderated sized shallow, serous, retinal detachments and PEDs in association with focal pigment epithelial leaks, a small subset of patients have been reported to present with large, bullous, serous retinal detachments. [1][2][3][4][5][6] Peripheral neovascularization, an uncommon finding in chronic CSC, is believed to be the result of retinal ischemia, which can develop in these dependent detachments once they become chronic. 3 These cases can be of diagnostic and therapeutic challenge, especially when occurring in the absence of contributing systemic conditions like corticosteroid therapy, hemodialysis, pregnancy, or organ transplantation.…”

Section: Discussionmentioning

confidence: 99%

Central Serous Chorioretinopathy and Peripheral Retinal Neovascularization

Barbazetto

Cinquini²,

Takahashi³

et al. 2009

RETINAL Cases &Amp; Brief Reports

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Patients with chronic CSC and a large, dependent serous detachment with peripheral retinal ischemia and neovascularization may be managed by focal treatment to active pigment epithelial leaks alone. This could spare patients of the adverse effects associated with widespread laser treatment and reduce the risk of visual loss due to vitreous hemorrhage and/or more severe complications resulting from progressive retinal ischemia.

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Section: Discussionmentioning

confidence: 99%

Central Serous Chorioretinopathy and Peripheral Retinal Neovascularization

Barbazetto

Cinquini²,

Takahashi³

et al. 2009

RETINAL Cases &Amp; Brief Reports

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“…4,17 The chronic and severe variants have been reported more frequently from the Asian countries than from the West. 33,34 We propose TTT as an effective and safe alternative to PDT for subfoveal treatment of persistent CSC with focal leaks. Adequate care should be exercised in applying this treatment in a subthreshold manner, to avoid complications like CNV and macular burn.…”

Section: Discussionmentioning

confidence: 99%

Transpupillary thermotherapy for subfoveal leaks in central serous chorioretinopathy

Shukla

Kolluru

Vignesh

et al. 2006

Eye

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Aim To evaluate transpupillary thermotherapy (TTT) for the treatment of subfoveal focal leaks in central serous chorioretinopathy (CSC). Methods The patients presenting with long-standing CSC, but without the features of chronicity, were offered the options of TTT, photodynamic therapy (for subfoveal leaks), photocoagulation (for extrafoveal leaks), or observation. The patients who opted for TTT or observation were enrolled in this study. TTT was performed using a spot diameter of 0.5 mm for 1 min. Best-corrected visual acuity (BCVA), status of macular detachment, and fluorescein angiographic status were evaluated at 1, 3, and 6 months. Results This study included 39 patients (40 eyes) with CSC between 4 and 12 months, of whom 25 patients (25 eyes) opted for TTT for subfoveal leaks. Fourteen patients (15 eyes) were followed up without treatment. The groups were comparable in age, sex, and baseline BCVA. Minimum follow-up was 6 months. Within 3 months, TTT resulted in the resolution of the serous detachment in 24 (96%) eyes with a single session; one eye required a repeat treatment. Eight control eyes demonstrated persisting CSC at the last follow-up. Visual acuity improved in 23 (92%) treated and five (33%) control eyes; the difference in outcome was statistically significant (Po0.001). One case developed choroidal neovascularization, which resolved with visual recovery to 20/20 after repeat-TTT. Conclusion TTT resulted in the resolution of CSC with subfoveal angiographic leaks with significant improvement in visual outcome, in comparison to the natural history of persistent CSC.

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“…CSC became exceptionally severe in our patient. An initial, apparently benign episode 16 years earlier progressively led, after many remissions and exacerbations, to uncommonly extended posterior pole lesions and to a very poor visual result in a professionally active Exceptionally severe cases of CSC have been described in association with corticosteroid administration [6,7]. In the present case, although corticosteroid use was denied, the disease progressed to one of the most severe variants.…”

Section: Discussionmentioning

confidence: 56%