Central Serous Chorioretinopathy and Peripheral Retinal Neovascularization

Barbazetto, Irene; Cinquini, Marco; Takahashi, Beatriz Sayuri; Yannuzzi, Lawrence A.

doi:10.1097/icb.0b013e31816b31e3

Cited by 2 publications

(6 citation statements)

References 14 publications

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“…In addition, some cases may be complicated by choroidal neovascularization, 15 retinal pigment epithelium rips, 16 or bullous dependent detachment. 17 However, we did not find these complications in our cases.…”

Section: Discussioncontrasting

confidence: 70%

Analysis of Optical Coherence Tomography in Acute versus Chronic Central Serous Chorioretinopathy

Jin

Lü

et al. 2021

Optom Vis Sci

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SIGNIFICANCE: Central serous chorioretinopathy (CSC) is a common retinal disease that causes vision loss worldwide. Studying the imaging characteristics of CSC is helpful for the differential diagnosis of diseases. This study analyzed the differences between acute and chronic CSC and provide related information. PURPOSE:The aim of this study was to describe the optical coherence tomography features in patients with acute and chronic CSC.METHODS: Sixty-two eyes of 56 patients with CSC were included in the study. Optical coherence tomography was performed to observe the image features. The photoreceptor outer-segment (PROS) thickness above the pigment epithelium detachment (PED) coinciding with the leakage point in fundus fluorescein angiography was measured and compared with the mean PROS thickness outside the PED in acute cases. The SPSS 23.0 software (IBM Co., Chicago, IL) was used for statistical analysis.RESULTS: Of our 56 patients (62 eyes), 41 (73.21%) were male and 15 (26.79%) were female. There were 53 eyes (85.48%) with acute CSC and 9 eyes (14.52%) with chronic CSC. Besides other common features, the new feature of a high-reflection band in the outer nuclear layer was found to be limited to the macular detachment area. In acute cases, the mean PROS thickness above the retinal pigment epithelium layer protuberance coinciding with the leakage point was 22.7 ± 8.8 μm, which was less than the mean PROS thickness outside the PED at 64.3 ± 21.3 μm ( P ≤ .001). CONCLUSIONS:The high-reflection band in the outer nuclear layer within the serous neurosensory detachment limited to the macular area was a new finding in CSC patients. This finding can be used as an imaging feature to aid in the diagnosis of CSC.

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Section: Discussioncontrasting

confidence: 70%

Analysis of Optical Coherence Tomography in Acute versus Chronic Central Serous Chorioretinopathy

Jin

Lü

et al. 2021

Optom Vis Sci

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“…This hyperfluorescence descends inferiorly conforming to the dependent retinal detachment [ 4 ]. Furthermore, slow and rather diffuse bilateral leakage attest diffuse decompensation of the RPE [ 22 ]. In particular, the crescent RPE tear appears as a window defect (the bare choroid) next to an hypofluorescence (the rolled RPE layer), in all angiographic phases if it has a crescent shape type [ 20 ].…”

Section: Resultsmentioning

confidence: 99%

“…In the case of peripheral retinal ischemia and neovascularization, wide-field FA can detect retinal capillaries obliteration and neovascularization with profuse leakages at the junction between perfused and non-perfused retina during the late angiographic phase [ 18 , 22 ]. Finally, no disk leak or vasculitis are detected [ 14 ].…”

Section: Resultsmentioning

confidence: 99%

“…In particular, the patient received one injection of Bevacizumab (1.25 mg) followed by one of Ranibizumab (0.5 mg) without performing a loading dose [ 21 ]. Besides, peripheral neovascularization complicating bCSCR, have been successfully treated with argon laser photocoagulation of leakage sites [ 22 ]. Therefore, further studies are warranted to clarify the possible anti-VEGF therapeutic role in bCSCR.…”

Section: Resultsmentioning

confidence: 99%

“…Eight articles were excluded: six not written in English, 1 review papers and 1 ex vivo studies. After full-text evaluation, 34 studies about bCSCR were included [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 17 , 18 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 31 , 32 , 33 , 35 , 36 , 37 , 38 , 39 , 40 ].…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Bullous Central Serous Chorioretinopathy: A Rare and Atypical Form of Central Serous Chorioretinopathy. A Systematic Review

et al. 2020

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Bullous central serous chorioretinopathy (bCSCR) is a rare variant of the central serous chorioretinopathy, complicated by an exudative retinal detachment with shifting fluid. This systematic review aims to present the epidemiology, the pathogenesis, the clinical presentation, the imaging, the differential diagnosis, and the latest treatments of this disease. A total of 60 studies were identified following a literature search adhering to PRISMA guidelines. After full-text evaluation, 34 studies about bCSCR were included. bCSCR usually affects middle-aged men, and the principal risk factor is corticosteroid medications. Pathogenesis is related to an increased choroidal vessel and choriocapillaris permeability, with subsequent subretinal fluid accumulation, rich in fibrin, which may provoke the exudative retinal detachment. Clinical presentation and imaging are fundamental to distinguish bCSCR from other pathologies, avoiding unappropriated treatment. Corticosteroid withdraws (if assumed) and laser photocoagulation of leakage sites seen at angiography may speed up retinal reattachment. Verteporfin photodynamic therapy, transpupillary thermal therapy, oral eplerenone and scleral thinning surgery are other therapeutic options. An early diagnosis might prevent disease progression due to harmful medications as well as unnecessary surgery.

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Central Serous Chorioretinopathy and Peripheral Retinal Neovascularization

Cited by 2 publications

References 14 publications

Analysis of Optical Coherence Tomography in Acute versus Chronic Central Serous Chorioretinopathy

Analysis of Optical Coherence Tomography in Acute versus Chronic Central Serous Chorioretinopathy

Bullous Central Serous Chorioretinopathy: A Rare and Atypical Form of Central Serous Chorioretinopathy. A Systematic Review

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