A light microscopic study of the development of the roots of premolar teeth in dogs

Owens, Phasefanie

doi:10.1016/0003-9969(74)90068-5

Cited by 33 publications

(19 citation statements)

References 24 publications

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“…Although it is widely held that acellular root cementum is formed by cementoblasts (e.g., Freeman, 19801, several authors have suggested that these cells are not involved in the production of a collagenous matrix (Paynter and Pudy, 1958;Selvig, 1963;Stern, 1964;Owens, 1974Owens, , 1975Beertsen et al, 1983). The present study provides further evidence for this view, but does not provide conclusive insight as to the origin of acellular cementum.…”

Section: Effects Of Hebp On Acellular Cementum Formationcontrasting

confidence: 71%

“…Many of the periodontal ligament fibrils had their origin in the mantle dentin matrix. In this respect our observations provide evidence for the view that the developing periodontal ligament may initially attach to the dentin without the formation of a cementum layer Won Brunn, 1891; Eccles, 1964;Owens, 1974Owens, , 1975. Under the conditions of the present study, collagen fibrils of the periodontal ligament seemed to originate somewhere from in the matrix-vesicle-rich region of the dentin.…”

Section: Effects Of Hebp On Acellular Cementum Formationsupporting

confidence: 46%

“…It is not entirely clear whether the two tissues are interconnected by their own matrix components (Von Brunn, 1891; Eccles, 1964;Owens, 1974Owens, , 1975 or whether they are cemented together by the organic and mineral phases of the developing cementum (Paynter and Pudy, 1958;Selvig, 1963Selvig, , 1964Lindskog, 1982).…”

mentioning

confidence: 98%

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Effects of 1‐hydroxyethylidene‐1, 1‐bisphosphonate (HEBP) on the formation of dentin and the periodontal attachment apparatus in the mouse

1985

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The effects of the bisphosphonate HEBP on dentin formation and the structural relationship between the dentin and the developing periodontal attachment apparatus have been studied in the continuously growing mouse incisor. It was observed that HEBP (in doses greater than or equal to 8 mg P/kg b.w/day) not only inhibited the deposition of mineral crystallites in newly formed dentin matrix, but also entirely prevented the formation of a layer of acellular root cementum. It was further noticed that the drug interfered with the deposition of 3H-serine-containing substances at the predentin-dentin border. This was not always accompanied by an inhibition of dentin mineralization, thereby suggesting that 3H-serine-containing proteins (presumably phosphoproteins) do not play a critical role in the deposition of mineral layers onto previously formed ones. The absence of a cementum layer did not prevent the developing periodontal ligament from establishing matrix-to-matrix connections with the root-analogue dentin. Collagen fibrils of the ligament intermingled with those of the mantle dentin, which in contrast to teeth not exposed to the drug were clearly visible and not masked by electron-dense matrix components. Finally, it was found that the drug had distinct effects on the formation of root-analogue and crown-analogue dentin. Whereas during the course of the experiment the odontoblasts along the crown-analogue aspect of the tooth continued to produce circumpulpal dentin matrix, those along the root-analogue aspect of the tooth did so only when the mantle dentin layer had been mineralized prior to HEBP administration. This phenomenon is interpreted as being indicative of fundamental differences between the formation of crown and root dentin.

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Section: Effects Of Hebp On Acellular Cementum Formationcontrasting

confidence: 71%

Section: Effects Of Hebp On Acellular Cementum Formationsupporting

confidence: 46%

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Effects of 1‐hydroxyethylidene‐1, 1‐bisphosphonate (HEBP) on the formation of dentin and the periodontal attachment apparatus in the mouse

1985

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“…It is a generally accepted fact that the breakup of the inner and outer cell layers of Hertwig's root sheath along the predentinldentin surface is due to epithelial cell degeneration (Avery, 1987;Freeman and Ten Cate, 1971;Furseth et al, 1986;Lester, 1969;Owens, 1974Owens, , 1978Slavkin, 1976). However, we observed that the cells of DFP project cytoplasmic processes from their leading edge towards and eventually into the intercellular spaces between the root sheath cells (Figs.…”

Section: Precementoblasf Stagementioning

confidence: 63%

“…There are the cells of the dental follicle proper (DFP), located nearest to the dental pulp and developing dentin surface, and the cells of the perifollicular mesenchyme (PFM), located more peripherally (Freeman and Ten Cate, 1971;Furseth et al, 1986;Lester, 1969;Owens, 1974;Selvig, 1964;Shibata and Stern, 1967;Ten Cate, 1980a,b). Their specific contributions to the development of the alveolus, PDL connective tissue, and cementum are still somewhat problematical.…”

Section: Fibroblasts During Root Formationmentioning

confidence: 97%