A Knowledge-Based Simulation Approach (K-SIM) for Train Operation and Planning

Sharma, Ghanshyam; Asthana, R.; Goel, Suneeti

doi:10.1177/003754979406200606

Cited by 6 publications

(5 citation statements)

References 5 publications

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“…The steady presence of tungsten for a month in drinking water leads to the inactivation of liver xanthine oxidase and its associated activities, i.e., inactive molecules of this enzyme are formed. As it is known, tungsten, as a chemical analog of molybdenum, is widely used to identify new molybdenum enzymes (Harrison, 2002;Schwarz, 2005;Sharma et al, 2016). Tungsten is very close to molybdenum in atomic and ionic radius, as well as chemical properties.…”

Section: Resultsmentioning

confidence: 99%

“…Thus, xanthine oxidase, contained in the tissue and liquids in the animal body, is a unique tool for decontamination of nitrates and nitrites and the formation of important substances for the body nitric oxide. This study aimed to determine the effect of heat treatment of milk on the activity and biological functions of xanthine oxidase in sheep liver in vivo (Sharma et al, 2016). To accomplish this goal, it is necessary to perform the following tasks: conducting an experiment on the activity of milk xanthine oxidase in the liver using the example of 3 control groups and determining their results, pointing out the differences, and conducting an experiment of xanthine oxidase activity during freezing and heating milk.…”

Section: Introductionmentioning

confidence: 99%

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The xanthine oxidase and its associated activities in the ovine milk and liver: distinctive in impact of in vivo molybdenum

Mukhamejanova

Alikulov

Туганова

et al. 2021

Potr. S. J. F. Sci.

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Xanthine oxidase is molybdenum and iron-containing flavoprotein, catalyzing the final oxidation stage of purines and oxidative transformation of pterins and some aliphatic and aromatic aldehydes. Despite the importance of this enzyme, the distribution of xanthine oxidase in traditional household animal’s milk and tissues is unknown. Formerly, we have found most of the xanthine oxidase molecules in animal milk are inactive because of a lack of molybdenum. Ovine milk was processed by inserting in vivo molybdenum (tungsten) into drinking water. We gave opposite dates in the presence of tungsten too. Heating the milk of animals at 80 °C for 5 minutes in the presence of molybdenum and cysteine led to a sharp increase of xanthine oxidase and its associated – nitrate reductase and nitrite reductase activities. The change of xanthine oxidase and its associated activities were examined by spectrophotometry after treatment. It was established that metal ions added in drinking water for animals have an impact on enzyme activities. The activity is formed in the ovine liver even in the absence of exogenous molybdenum in drinking water. The associated activities of liver enzymes in the presence of molybdenum in drinking water had slightly increased. Tungsten-containing water led to the loss of all activities of liver xanthine oxidase. It is proposed that the liver contains a special protein involving in the incorporation of molybdenum (or tungsten) into xanthine oxidase molecule, however, the milk or mammary gland compounds lack this protein.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The xanthine oxidase and its associated activities in the ovine milk and liver: distinctive in impact of in vivo molybdenum

Mukhamejanova

Alikulov

Туганова

et al. 2021

Potr. S. J. F. Sci.

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“…They also work in collaboration with (and usually under the supervision of) doctors, nurses, and other healthcare providers to deliver the prescribed healthcare services to their patients. [4] Multifactorial "work-related" diseases are often more common than occupational diseases and therefore they deserve adequate attention by the health services. [5] Healthcare profession is known to be at a high risk for work related musculoskeletal disorders (WMSDs).…”

Section: Introductionmentioning

confidence: 99%

To Assess Pain and Risk of Work-Related Musculoskeletal Disorders in Home Health Care Providers of Pune City

Jadhav,

Thodge,

Jerome

2024

Int J Health Sci Res

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This study aimed to assess pain and risk of work-related musculoskeletal disorders amongst home health care providers of Pune City. The current observational study included 114 participants who had completed the General Duty Assistant course and had more than 1 year of experience. The outcome measures used were Numeric Pain Rating Scale and Rapid Entire Body Assessment. The participants filled the evaluation proforma. In pain evaluation, they specified of having any musculoskeletal pain as well as the pain location. The participants rated their pain on Numeric Pain Rating Scale. Then, the major tasks were identified. Rapid Entire Body Assessment was evaluated while the participants were performing their tasks. The results showed that in pain evaluation, 73.68% experienced musculoskeletal pain at present. The distribution of pain locations states that 46% had pain in the back, 20% in the neck, 19% in the shoulders, 13% in the knees and 1% in the wrist and foot. Using Numeric Pain Rating Scale, the participants had moderate pain on activity (4-6) while the participants had none pain at rest (0). The participants had a high-risk score of 8.53 while they performed patient transfers activities. The study concluded that home health care providers had moderate pain on activity with maximum pain in the back region. The home health care providers are majorly involved in patient transfers activities followed with patient grooming activities. They had a medium to high risk of acquiring work-related musculoskeletal disorders. Key words: Home health care providers, work- related musculoskeletal disorders, General Duty Assistant, Numeric Pain Rating Scale, Rapid Entire Body Assessment Scale, Pune City.

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“…Kesling and Whittaker 17 proposed the simulation model to analyze the structural reliability of rails under train schedules. Sharma et al 18 established the decision support system utilizing the techniques of artificial intelligence, simulation and operational research for the train operation planning. Dessouky and Leachman 19 proposed the simulation modeling methodology to analyze the performances of a complex railway network, such as delay and capacity.…”

Section: Introductionmentioning

confidence: 99%

Modeling and simulation of train movements under scheduling and control for a fixed-block railway network using cellular automata

Zhou

2013

SIMULATION

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The dynamics of train movements is not only determined by the control strength of the train, but also by the interdependence between trains and the scheduling command that specifies the allowable movement distance and speed. This paper attempts to propose a generalized simulation model of train movements using cellular automata so that the scheduling commands are incorporated into the model. Based on the concept of instantaneous movement authority, the proposed model generally decomposes the entire trip into a series of movements on each block section with speed limits at the start and endpoints of, as well as within, the section. It realizes the dynamic speed updates analogous to the feedback adjustments of realistic train movements, and describes both the dynamics of the train itself and the interactions between trains with adjustable parameters. The control strategies are reflected in the configurations of the acceleration and the deceleration. The autonomous, restrictive and synergistic aspects of train movements are completely represented. The model and the simulation algorithm are applied to simulate the train movements with and without the scheduling commands. The observed phenomena can be replicated, and the rationality of simulation results has been analyzed about the speed updates and the performances under the typical scheduling strategies. The proposed simulation model can facilitate the establishment of measures to maximize the transport efficiency of the railway network.

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A Knowledge-Based Simulation Approach (K-SIM) for Train Operation and Planning

Cited by 6 publications

References 5 publications

The xanthine oxidase and its associated activities in the ovine milk and liver: distinctive in impact of in vivo molybdenum

The xanthine oxidase and its associated activities in the ovine milk and liver: distinctive in impact of in vivo molybdenum

To Assess Pain and Risk of Work-Related Musculoskeletal Disorders in Home Health Care Providers of Pune City

Modeling and simulation of train movements under scheduling and control for a fixed-block railway network using cellular automata

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