A HKUST-1 MOF inclusion compound with in-situ reduced copper(I) as [Cu(NCCH3)4]+ cation complex in the octahedral A-type pore

Tahli, Anas; Elshaarawy, Reda F.M.; Köc, Ümit; Kautz, Anna Christin; Janiak, Christoph

doi:10.1016/j.poly.2016.06.039

Cited by 13 publications

(6 citation statements)

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“…In addition, distinctive properties make MOF-NPs have considerable several applications like sensing, biomedical, drug delivery gas separation/storage, catalysis, etc. [34][35][36][37][38][39] In the present work, a novel nanoparticles of Zn(II) metal-organic framework (Zn-MOF-NPs) was prepared via reaction of zinc acetate with nano organic linker previously prepared [37]. The prepared Zn(II)-MOF-NPs was characterized using various micro/analytical techniques for proving the structure and morphology.…”

Section: Introductionmentioning

confidence: 99%

WITHDRAWN: Zn(II) Metal-organic Framework Nanoparticles: Synthesis, Characterization and Application as Optical Biosensor for Prostate-Specific Antigen

El‐Sheikh

2021

Preprint

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PSA, abbreviated of “Prostate-Specific Antigen” is widely used as a considered a significant cancer biomarker for diagnosing prostate cancer. Improvement of a fast, facile, and less cost with high accurate/sensitive/selective methodologies for the PSA determination is stock-still a challenge. In this work, we reported a simple biosensor based on a Zn(II) metal-organic framework nanoparticles (Zn-MOF-NPs) derived from reaction of zinc acetate with nano organic linker. The structure, morphology, and physicochemical properties of the prepared Zn(II)-MOF-NPs were definite using various spectroscopic and microanalytical tools as SEM-EDX, HR-TEM, XRD, XPS, elemental analysis, FT-IR, UV-vis spectroscopy, mass spectroscopy, thermogravimetric Analysis (DSC/TGA), and photoluminescence (PL). Obviously, the results revealed that the Zn(II)-MOF-NPs is chemical stable, highly selective and sensitive to PSA, without interferences with other common interfering analytes. The detection limit for PSA was 0.145 fg/mL, in a wide-linear range of concentrations (0.1 fg/mL-20 pg/mL), with a correlation coefficient 0.983. The Zn(II)-MOF-NPs was successfully used as an up-and-coming biosensor for PSA-monitoring and quantification in biological real samples (plasma/whole blood/serum) at clinical target concentration levels. Moreover, the present approach will help the human-beings from the hazard’s prostatic cancer through early discovery and diagnosis process via the detection of PSA at low limits of concentrations. Meantime, the interaction mechanism between the Zn(II)-MOF-NPs and PSA was well studied and investigated.

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Section: Introductionmentioning

confidence: 99%

WITHDRAWN: Zn(II) Metal-organic Framework Nanoparticles: Synthesis, Characterization and Application as Optical Biosensor for Prostate-Specific Antigen

El‐Sheikh

2021

Preprint

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“…46–49 These materials are currently receiving a lot of attention because of the many different ways in which they can be used, as well as their excellent thermal and chemical stability, high surface area, and manageable pore size. 50–59…”

Section: Introductionmentioning

confidence: 99%

A novel test device and quantitative colorimetric method for the detection of human chorionic gonadotropin (hCG) based on Au@Zn–salen MOF for POCT applications

Mohamed¹,

El‐Sheikh

Kadi³

et al. 2023

RSC Adv.

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“…MOF-NPs, due to their superior physicochemical characteristics, are very selective and sensitive methods for forming bonds with both organic and biological molecules, and they may be dealt with more effectively than the rest of the components by relatively simple means [ 52 ]. In addition, MOF-NPs’ unique features allow them to be used in a wide range of fields, from sensing and biomedical to drug delivery and gas separation/storage, to catalysis and beyond [ 53 , 54 , 55 , 56 , 57 , 58 ].…”

Section: Introductionmentioning

confidence: 99%

Prostate-Specific Antigen Monitoring Using Nano Zinc(II) Metal–Organic Framework-Based Optical Biosensor

et al. 2022

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Background: The prostate-specific antigen (PSA) is an important cancer biomarker that is commonly utilized in the diagnosis of prostate cancer. The development of a PSA determination technique that is rapid, simple, and inexpensive, in addition to highly accurate, sensitive, and selective, remains a formidable obstacle. Methods: In this study, we developed a practical biosensor based on Zn(II) metal–organic framework nanoparticles (Zn-MOFs-NPs). Many spectroscopic and microanalytical tools are used to determine the structure, morphology, and physicochemical properties of the prepared MOF. Results: According to the results, Zn-MOFs-NPs are sensitive to PSA, selective to an extremely greater extent, and stable in terms of chemical composition. Furthermore, the Zn-MOFs-NPs did not exhibit any interferences from other common analytes that might cause interference. The detection limit for PSA was calculated and was 0.145 fg/mL throughout a wide linear concentration range (0.1 fg/mL–20 pg/mL). Conclusions: Zn-MOFs-NPs were successfully used as a growing biosensor for the monitoring and measurement of PSA in biological real samples.

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A HKUST-1 MOF inclusion compound with in-situ reduced copper(I) as [Cu(NCCH3)4]+ cation complex in the octahedral A-type pore

Cited by 13 publications

References 85 publications

WITHDRAWN: Zn(II) Metal-organic Framework Nanoparticles: Synthesis, Characterization and Application as Optical Biosensor for Prostate-Specific Antigen

WITHDRAWN: Zn(II) Metal-organic Framework Nanoparticles: Synthesis, Characterization and Application as Optical Biosensor for Prostate-Specific Antigen

A novel test device and quantitative colorimetric method for the detection of human chorionic gonadotropin (hCG) based on Au@Zn–salen MOF for POCT applications

Prostate-Specific Antigen Monitoring Using Nano Zinc(II) Metal–Organic Framework-Based Optical Biosensor

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