A highly sensitive and specific capacitive aptasensor for rapid and label-free trace analysis of Bisphenol A (BPA) in canned foods

Mirzajani, Hadi; Cheng, Cheng; Wu, Jayne; Chen, Jiangang; Eda, Shigetoshi; Aghdam, Esmaeil Najafi; Ghavifekr, Habib Badri

doi:10.1016/j.bios.2016.09.109

Cited by 80 publications

(21 citation statements)

References 51 publications

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“…While several PCB-implemented electrochemical biosensors are being increasingly demonstrated over the past few years for several applications [4][5][6][7][8][9], little care is being given to the sensing electrode characteristics and their significance in sensor characteristics. Nonetheless, in the case of sensors exploiting SAM-assisted capture molecule immobilization, the physical and chemical properties of the electrodes can severely affect the sensing characteristics.…”

Section: Introductionmentioning

confidence: 99%

Commercially Fabricated Printed Circuit Board Sensing Electrodes for Biomarker Electrochemical Detection: The Importance of Electrode Surface Characteristics in Sensor Performance

2018

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Here we report the first PCB-implemented electrochemical glucose biosensor usingcovalently immobilized glucose oxidase (GOx) on the commercially fabricated PCB electrodesurface, taking particular care on the electrode surface characteristics and their effect on sensorperformance. Based on the results, this assay exhibits a highly linear response from 500 μM to 20mM (R = 0.9961) and a lower limit of detection of 500 μM.

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Section: Introductionmentioning

confidence: 99%

Commercially Fabricated Printed Circuit Board Sensing Electrodes for Biomarker Electrochemical Detection: The Importance of Electrode Surface Characteristics in Sensor Performance

2018

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“…In recent years, microfluidic chips have aroused increasing interest for various application because of their desirable features, such as the smaller sample amount needed and lowered reagent consumption. The substrate materials of microfluidic chips such as polymers (e.g., PDMS, PMMA, PS) [ 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ], ceramics (e.g., glass) [ 6 , 13 , 14 , 16 , 17 , 18 , 19 , 21 , 25 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 ], and semiconduct...…”

Section: Classification Of Microdevicesmentioning

confidence: 99%

Recent Microdevice-Based Aptamer Sensors

et al. 2018

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Since the systematic evolution of ligands by exponential enrichment (SELEX) method was developed, aptamers have made significant contributions as bio-recognition sensors. Microdevice systems allow for low reagent consumption, high-throughput of samples, and disposability. Due to these advantages, there has been an increasing demand to develop microfluidic-based aptasensors for analytical technique applications. This review introduces the principal concepts of aptasensors and then presents some advanced applications of microdevice-based aptasensors on several platforms. Highly sensitive detection techniques, such as electrochemical and optical detection, have been integrated into lab-on-a-chip devices and researchers have moved towards the goal of establishing point-of-care diagnoses for target analyses.

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“…21 However, these techniques are expensive and required complicated instruments, skilled operators and time-consuming pretreatment steps, which restrict their usability towards broad applications. Hence, few other methods such as fluorimetry, 22 enzyme-linked immunosorbent assay, 23 aptamer based assay, 24 flow injection chemiluminescence 25 and electrochemical methods 26 have been developed for BPA detection towards further significant progress. However, the use of probe molecules based methods such as antibody, enzyme and aptamer as a recognition element for BPA is expensive and complicated due to the risk of stability, multistep immobilization process of biomolecules and non-specific binding of the probe molecules towards BPA analogs.…”

Section: Graphical Abstractmentioning

confidence: 99%

Development of Bis-Phenol A sensor based on Fe2MoO4·Fe3O4·ZnO nanoparticles for sustainable environment

Subhan

Saha

Alam

et al. 2018

Journal of Environmental Chemical Engineering

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A versatile nano-molybdenum-iron-zinc-oxide (Fe2MoO4•Fe3O4•ZnO) nanoparticles (NPs) were prepared by co-precipitation method. The as-synthesized catalyst was characterized by several analytical techniques such as XRD, SEM, and FTIR spectroscopy. From the XRD pattern, particle size of the synthesized nanocomposite was calculated and found to be 20.5 nm. Elemental composition and their homogenies distribution in Fe2MoO4•Fe3O4•ZnO was confirmed by EDS study. The proposed Bis-phenol (BPA) chemical sensor with active Fe2MoO4•Fe3O4•ZnO NPs displays good selectivity with lower detection limit (DL) and longterm stability with enhanced electrochemical response. The calibration plot is linear (r 2 : 0.9978) over the concertation range (LDR) of 0.1 nM0.1 mM of BPA. The calculated sensitivity is 2.2468 µAµM-1 cm-2 with detection limit (DL) of 42.25±2.11pM at signal to noise ratio of 3(S/N). The BPA chemical sensor fabricated with Fe2MoO4•Fe3O4•ZnO NPs may be a promising with high sensitivity in reliable I-V method. Thus, this novel effort initiates a well-organized way to the development of reliable Fe2MoO4•Fe3O4•ZnO NPs/binder/GCE chemical sensor for efficiently detection of real hazardous toxins in environment as well as health career sector in a broad scale.

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A highly sensitive and specific capacitive aptasensor for rapid and label-free trace analysis of Bisphenol A (BPA) in canned foods

Cited by 80 publications

References 51 publications

Commercially Fabricated Printed Circuit Board Sensing Electrodes for Biomarker Electrochemical Detection: The Importance of Electrode Surface Characteristics in Sensor Performance

Commercially Fabricated Printed Circuit Board Sensing Electrodes for Biomarker Electrochemical Detection: The Importance of Electrode Surface Characteristics in Sensor Performance

Recent Microdevice-Based Aptamer Sensors

Development of Bis-Phenol A sensor based on Fe2MoO4·Fe3O4·ZnO nanoparticles for sustainable environment

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