A gold nanoparticles - Graphene based electrochemical sensor for sensitive determination of nitrazepam

Fritea, Luminița; Bănică, Florin; Costea, T.; Moldovan, Liviu; Iovan, Ciprian; Cavalu, Simona

doi:10.1016/j.jelechem.2018.10.015

Cited by 37 publications

(24 citation statements)

References 36 publications

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“…Nowadays, the tendency in pharmaceutical and food industries is to replace synthetic antioxidants with the natural ones. For these reasons there is a growing interest in analyzing natural, healthy and non-toxic additives as potential antioxidants [ 28 , 37 , 38 ]. Some plants, which contain high level of phenolic compounds, present an increasing interest in medicine due to their ability to scavenge free radicals [ 39 , 40 , 41 ].…”

Section: Pharmacological Activitiesmentioning

confidence: 99%

Perspectives on the Combined Effects of Ocimum basilicum and Trifolium pratense Extracts in Terms of Phytochemical Profile and Pharmacological Effects

Mintas

Miere

Fritea

et al. 2021

Plants

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Nowadays, the tendency in pharmaceutical and food industries is to replace synthetic antioxidants with the natural ones. For this reason, there is a growing interest in analyzing natural, healthy and non-toxic additives as potential antioxidants. Some plants, which contain high levels of phenolic compounds, present an increasing interest for medicine due to their ability to scavenge free radicals, along with other pharmacological activities, such as antibacterial activity, wound healing and anti-inflammatory effect, to mention only a few. The aim of this review is to explore the therapeutic potential of Ocimum basilicum and Trifolium pratense in relation with their phytochemical profile and to highlight the pharmacological activity of aqueous or ethanol extracts. Special attention was devoted to the dermal pathology and wound healing effects, in the context of multiple skin conditions such as acne, eczema boils, psoriasis and rashes. Additionally, both extracts (Trifolium sp. and Ocimum sp.) are characterized by high content of antioxidant compounds, which are responsible for the radiance and resistance of the skin and slowing down of the aging process by maintaining estrogen levels. Moreover, the potential combined effect of the mixed extract is pointed out in terms of future applications for wound healing, based on some preliminary results obtained from a “scratch tests” assay performed with respect to human dermal fibroblasts.

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Section: Pharmacological Activitiesmentioning

confidence: 99%

Perspectives on the Combined Effects of Ocimum basilicum and Trifolium pratense Extracts in Terms of Phytochemical Profile and Pharmacological Effects

Mintas

Miere

Fritea

et al. 2021

Plants

Self Cite

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“…In this study the results confirm the microbiological stability of the tested product. In order to keep regulations comming out from above mentioned ISO and EN standards it will be necessary to continue in this research and test the stability of cosmetics products from the point of their odourfor instance by employing electrochemical sensors [31,32].…”

Section: Resultsmentioning

confidence: 99%

Study on the Stability and Compatibility of the Cosmetic Products with Lavandula angustifolia Oil Kept in PPH Polypropylene Homopolymer Plastic Containers

Bogdan¹,

Endres²,

Pasca³

et al. 2019

Mat.Plast.

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The products used in cosmetic formulations are continuously diversifying as a result of researches in the field, which combine the healing and prevention of many skin conditions with the use of natural products such as vegetable extracts and essential oils. Testing the stability and compatibility of new or modified cosmetics is required to ensure that quality standards are met when stored in proper conditions for functionality and aesthetics, to preserve their chemical, microbiological and physical properties. In this study, the stability and compatibility of a new cosmetic product containing lavender essential oil in plastic container-plastic jar 100 mL PPH Polypropylene homopolymer (Moplen HP648T) is tested against the glass receptacle used as a control. The monitored parameters were organoleptic characteristics (appearance, color, fragrance), physicochemical (pH, density), under controlled temperature conditions, and the microbiological ones. The results of this study showed that the tested cosmetic product is compatible with the plastic container; data obtained were comparable with the organoleptic and physicochemical test results obtained in the case of the control sample stored at room conditions.

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“…CNTs were dispersed in this solution so as to obtain a solution of concentration 1 mg CNTs/mL, in an ultrasonication bath SONOREX SUPER (Bandelin-Electronic GmbH & Co. KG, Berlin, Germany), at a temperature of 25 ± 2 • C, for 30 min (1 mg/mL CNTs/CS 5%/GCE). Another suspension prepared for electrode modification contained 20 mg CNTs/mL 0.5% CS solution in 2% acetic acid solution (20 mg/mL CNTs/CS 0.5%/GCE) [32,33]. CS has the role of fixing the strong electroactive material of CNTs to the surface of the glassy carbon electrode.…”

Section: Preparation Of Cnts In Csmentioning

confidence: 99%

Determination of the Total Polyphenols Content and Antioxidant Activity of Echinacea Purpurea Extracts Using Newly Manufactured Glassy Carbon Electrodes Modified with Carbon Nanotubes

et al. 2020

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A sensitive electrochemical method was used for the determination of the total phenolic content and antioxidant activity of Echinacea purpurea extracts. In this study, 3 glassy carbon electrodes (GCE) were used: one unmodified and the other two newly manufactured glassy carbon electrodes modified with carbon nanotubes (CNTs) and chitosan (CS) in different concentrations, having the following composition: 1 mg/mL CNTs/CS 5%/GCE and 20 mg/mL CNTs/CS 0.5%/GCE. The determinations were performed on 3 different pharmaceutical forms (capsules, tablets and tincture), which contain E. pururea extract from the root or aerial part of the plant. Standard chicoric and caftaric polyphenolic acids, as well as food supplements extracts, were characterized using voltammetry, in a Britton-Robinson (B-R) electrolyte buffer. The modified 1 mg/mL CNTs/CS 5%/GCE electrode has superior properties compared to the other two (the unmodified and 20 mg/mL CNTs/CS 0.5%/GCE-modified) electrodes used in the study. Echinacea tincture had the highest antioxidant capacity and the biggest total amount of polyphenols (28.72 mg/equivalent of 500 mg powder). Echinacea capsules had the lowest antioxidant capacity, but also the lowest total amount of polyphenols (19.50 mg/500 mg powder); similarly, tablets had approximately the same values of polyphenols content (19.80 mg/500 mg powder), and also antioxidant capacity. The total polyphenol content was consistent with the one indicated by the manufacturers. Pulse-differential cyclic voltammetry represents a rapid, simple and sensitive technique to establish the entire polyphenolic amount and the antioxidant activity of the E. purpurea extracts.

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A gold nanoparticles - Graphene based electrochemical sensor for sensitive determination of nitrazepam

Cited by 37 publications

References 36 publications

Perspectives on the Combined Effects of Ocimum basilicum and Trifolium pratense Extracts in Terms of Phytochemical Profile and Pharmacological Effects

Perspectives on the Combined Effects of Ocimum basilicum and Trifolium pratense Extracts in Terms of Phytochemical Profile and Pharmacological Effects

Study on the Stability and Compatibility of the Cosmetic Products with Lavandula angustifolia Oil Kept in PPH Polypropylene Homopolymer Plastic Containers

Determination of the Total Polyphenols Content and Antioxidant Activity of Echinacea Purpurea Extracts Using Newly Manufactured Glassy Carbon Electrodes Modified with Carbon Nanotubes

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