A fatal case of necrotizing Aeromonas schubertii fasciitis after penetrating injury

Kao, Ta-Lun; Kao, Man-Ling

doi:10.1016/j.ajem.2010.10.028

Cited by 15 publications

(18 citation statements)

References 11 publications

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“…Aeromonas schubertii was named for a group of mesophilic strains formerly designated Enteric Group 501 by the Centers for Disease Control. Aeromonas schubertii may have a predilection for causing serious disease in humans (Hickman-Brenner et al 1988;Carnahan et al 1989;Kao & Kao 2011). Most human A. schubertii isolates were isolated from moderate-to-severe wound infections or from sterile body fluids and, unlike other aeromonads associated with human disease, were not recovered from gastrointestinal specimens (Carnahan et al 1989).…”

Section: Introductionmentioning

confidence: 99%

Isolation and characterization of Aeromonas schubertii from diseased snakehead, Channa maculata (Lacepède)

Chen

Liang

Zhuo

et al. 2012

Journal of Fish Diseases

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Pure bacterial cultures were isolated from diseased snakeheads, Channa maculata (Lacepède), suffering high mortality in a farm in Zhongshan, southern China. Three isolates, namely ZS20100725, ZS20100725-1 and ZS20100725-2, were identified as Aeromonas schubertii. All the isolates showed high 16S rRNA sequence similarities with A. schubertii. The isolates exhibited strong virulence to snakeheads in experimental challenges with LD(50) ranging between 1.4 × 10(4) and 6.4 × 10(6) CFU g(-1). Two of the isolates were positive for haemolysin, elastase, lipase and lecithinase by phenotypic determination, which was further confirmed by PCR amplification of the haemolysin and elastase genes. In sterile liquid medium, the best growth conditions of strain ZS20100725 were 30 °C, pH 7 and 0.5% salinity (w/v). Antibiotic susceptibility tests showed that strain ZS20100725 was susceptible to cefoxitin, cefoperazone and chloramphenicol. Furthermore, histopathology of diseased snakeheads infected with A. schubertii showed necrosis and congestion in liver, kidney and spleen and also damage to the cardiac muscle, intestine and gills.

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Section: Introductionmentioning

confidence: 99%

Isolation and characterization of Aeromonas schubertii from diseased snakehead, Channa maculata (Lacepède)

Chen

Liang

Zhuo

et al. 2012

Journal of Fish Diseases

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“…Although most cases of diarrhea or colitis have been described in immunocompetent patients, Aeromonas-related diarrhea has also been reported in immunocompromised subjects. The most frequents are skin or soft tissue infections, such as cellulitis 41 or fasciitis, [42][43][44] cholangitis, 45 and septicemia. The most frequents are skin or soft tissue infections, such as cellulitis 41 or fasciitis, [42][43][44] cholangitis, 45 and septicemia.…”

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Aeromonas Species

Lobatón

Hoffman

Vermeire

et al. 2015

Inflammatory Bowel Diseases

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“…There are several pathways through which humans become colonized/infected with The risk of infection in people should also be considered when handling animals, mainly prawns and fish (Kao and Kao 2012).…”

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Virulence and antimicrobial susceptibility of clinical and environmental strains of Aeromonas spp. from northeastern Brazil

et al. 2015

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The aims of the present study were to isolate and identify clinical and environmental strains of Aeromonas spp. by means of biochemical tests and the automated method VITEK 2 and to investigate the presence of the virulence genes cytotoxic enterotoxin (act), hemolysin (asa-1), and type III secretion system (ascV), and also the in vitro antimicrobial susceptibility of the strains. From the clinical isolates, 19 Aeromonas hydrophila, 3 Aeromonas veronii bv. sobria, and 1 Aeromonas caviae were identified, while from the environmental strains, 11 A. hydrophila, 22 A. veronii bv. sobria, 1 A. veronii bv. veronii, and 1 A. caviae were recovered. The gene act was detected in 69.5% of clinical isolates, asa-1 in 8.6%, and ascV in 34.7%. In the environmental strains, the detection rates were 51.4%, 45.7%, and 54.2% for the genes act, asa-1, and ascV, respectively. Resistance to amoxicillin-clavulanate and piperacillin-tazobactam was observed in 15 and 3 clinical strains, respectively, and resistance to ceftazidime, meropenem, imipenem, ciprofloxacin, and trimethoprim-sulfamethoxazole was observed in 1 strain for each drug. Resistance to amoxicillin-clavulanate and piperacillin-tazobactam was detected in 17 and 1 environmental strain, respectively. Higher resistance percentages were observed in clinical strains, but environmental strains also showed this phenomenon and presented a higher detection rate of virulence genes. Thus, it is important to monitor the antimicrobial susceptibility and pathogenic potential of the environmental isolates.

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A fatal case of necrotizing Aeromonas schubertii fasciitis after penetrating injury

Cited by 15 publications

References 11 publications

Isolation and characterization of Aeromonas schubertii from diseased snakehead, Channa maculata (Lacepède)

Isolation and characterization of Aeromonas schubertii from diseased snakehead, Channa maculata (Lacepède)

Aeromonas Species

Virulence and antimicrobial susceptibility of clinical and environmental strains of Aeromonas spp. from northeastern Brazil

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