A Demographic Study of Disease due to Mycobacterium kansasii or M intracellulare-avium in Texas

Epidemiology of Infection by Nontuberculous Mycobacteria

“…Whether one or the other predominated depended upon the locale; M. kansasii disease was mostly urban, with many cases in the central United States (5). M. intracellulare and M. avium disease was principally rural and centered in the southeastern United States (5).…”

“…M. intracellulare and M. avium disease was principally rural and centered in the southeastern United States (5). In some regions, the incidence of disease caused by nontuberculous mycobacteria was increasing (5).…”

“…In fact, over the period from 1953 through 1970, there was an increase in the incidence of M. kansasii infections in Wales (387). In Texas, over the period from 1967 to 1976, there was an increase in the number of cases of M. kansasii infection and there were approximately twice the number of M. kansasii cases as M. avium complex cases (5). The number of M. kansasii isolates submitted to the Centers for Disease Control and Prevention is quite variable (174,176), and certain areas, including Louisiana, have large numbers (546).…”

“…In a demographic study of pulmonary disease caused by M. kansasii in Texas, it was reported that cases were significantly more likely to come from urban than rural areas and that patients were unlikely to have Spanish surnames (5). In Japan, most M. kansasii lung infections were found in Tokyo (501,503).…”

Immunosuppression and mycobacteria other thanMycobacterium tuberculosis: results from patients with and without HIV infection

“…In immunocompetent individuals more than the half of these atypical mycobacterioses are caused by M. kansasii (5), while the rest of these infections commonly is due to the Mycobacterium avium-Mycobacterium intracellulare complex (MAI) (6). In normal hosts disseminated rnycobacterial infections are rare (7) and generally associated with malignancy or corticosteroid therapy (8)(9)(10).…”