A confirmatory method for the determination of tetracyclines in muscle using high-performance liquid chromatography with diode-array detection

Cristofani, Elisa; Antonini, Chiara; Tovo, Gloria Raquel; Fioroni, Laura; Piersanti, Arianna; Galarini, Roberta

doi:10.1016/j.aca.2008.10.029

Cited by 42 publications

(22 citation statements)

References 16 publications

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“…Tetracyclines were determined applying the method by Cristofani et al (2009) with some minor amendments. After the milk defatting procedure, the compounds were extracted with a mixture of 0.1 M succinic acid (pH 4.0) and methanol.…”

Section: High Performance Liquid Chromatography Methodsmentioning

confidence: 99%

“…Many chromatographic confirmatory methods have been developed for the determination of antibiotics (Cinquina, Longo, & Anastasi, 2003;Cristofani et al, 2009;Di Corcia & Nazzari, 2002;Juan, Moltó, Mañes, & Font, 2010;Makeswaran, Patterson, & Points, 2005;Mamani, Reyes, & Rath, 2009;McGlinchey, Rafter, Regan, & McMahon, 2008;Msagati & Nindi, 2007;Oka, Ito & Matsumoto, 2000;Spisso et al, 2009;Van Rhijn, Lasaroms, Berendsen, & Brinkman, 2002).…”

Section: Introductionmentioning

confidence: 99%

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Veterinary drug residues determination in raw milk in Croatia

et al. 2011

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Section: High Performance Liquid Chromatography Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Veterinary drug residues determination in raw milk in Croatia

et al. 2011

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“…The total analysis time was 6 min for the monolithic column and 50 min for the conventional column. Determination of tetracyclines (oxytetracycline, tetracycline, chlortetracycline, and doxycycline) and their 4-epimers (4-epioxytetracycline, 4-epitetracycline, and 4-epichlortetracycline) in animal tissues (muscle) [13] was developed in the basis of a monolithic column of 50 mm length with a total analysis time of less than 8 min. The new method was compared to that using the original LUNA C18 column for which the analysis time was 24 min.…”

Section: Introductionmentioning

confidence: 99%

Application of monolithic columns in pharmaceutical analysis. Determination of indomethacin and its degradation products

Žáková

Sklenářová

Nováková

et al. 2009

J of Separation Science

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Comparison of HPLC methods using conventional particle-based and monolithic columns for determination of indomethacin and its two degradation products, viz. 5-methoxy-2-methylindoleacetic acid and 4-chlorobenzoic acid, was carried out. Ketoprofen was used as an internal standard for data evaluation throughout the study. Conventional separation was based on analytical column Zorbax SB-Phenyl (75x4.6 mm; 3.5 microm particles) used with a mobile phase composition of acetonitrile and phosphoric acid 0.2% (50:50, v/v) and isocratic flow at 0.6 mL/min. Three different lengths of Chromolith columns RP-18e (25x4.6 mm, 50x4.6 mm, and 100x3 mm) were tested with respect to the validation parameters peak asymmetry, resolution, height equivalent to a theoretical plate, repeatability, and after optimisation compared to values obtained using a conventional Zorbax column. The developed methods were used to determine all three compounds in a pharmaceutical formulation--Indobene gel. Chromatographic parameters were comparable to those of a conventional particle-based column. The analysis time was shortened as expected (retention times were lowered by a factor of two). Moreover, the repeatability of peak areas and retention times obtained with a 50 mm monolithic column was greatly improved (RSD values were lower than 0.40%).

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“…[343]. Other groups have developed more novel clean-up procedures using dispersive SPME [344] and metal chelate affinity chromatography (MCAC) [345].…”

Section: Tetracyclinesmentioning

confidence: 99%

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

Kinsella

O’Mahony

Malone

et al. 2009

Journal of Chromatography A

180

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A comprehensive review is presented on the current trends in sample preparation for isolation of veterinary drugs and growth promotors from foods. The objective of the review is to firstly give an overview of the sample preparation techniques that are applied in field. The review will focus on new techniques and technologies, which improve efficiency and coverage of residues. The underlying theme to the paper is the developments that have been made in multi-residue methods and particularly multi-class methods for residues of licensed animal health products, which have been developed in the last couple of years. The role of multi-class methods is discussed and how they can be accommodated in future residue surveillance.

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A confirmatory method for the determination of tetracyclines in muscle using high-performance liquid chromatography with diode-array detection

Cited by 42 publications

References 16 publications

Veterinary drug residues determination in raw milk in Croatia

Veterinary drug residues determination in raw milk in Croatia

Application of monolithic columns in pharmaceutical analysis. Determination of indomethacin and its degradation products

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

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