Mathematical Human Body Models (HBM) are important research tools that are used to study the human response in car crash situations. Development of automotive safety systems requires the implementation of active muscle response in HBM, as novel safety systems also interact with vehicle occupants in the precrash phase. In this study, active muscle response was implemented using feedback control of a non-linear muscle model in the right upper extremity of a Finite Element (FE) HBM. Hill-type line muscle elements were added and the active and passive properties were assessed. Volunteer tests with low impact loading resulting in elbow flexion motions were performed. Simulations of posture maintenance in a gravity field and the volunteer tests were successfully conducted. It was concluded that feedback control of a non-linear musculoskeletal model can be used to obtain posture maintenance and human-like reflexive responses in an FE HBM.Keywords: finite element; human body model; active muscle; feedback control; posture maintenance; upper extremity 2 1 Introduction Road traffic accidents are among the top leading causes of death worldwide. In the European Union, there are about 43,000 reported deaths (ETSC 2008) and 1.3 million casualties because of road traffic accidents each year (European Commission 2001). To prevent accidental injuries, it is vital to understand the mechanics of injury in biological tissues. For traffic safety research addressing this problem Human Body Models (HBM) are important tools. The HBM can be Multi Body (MB) or Finite Element (FE) models. The MB models consist of rigid bodies connected with joints defined by kinematical constraints and can predict occupant kinematics at a relatively low computational cost with relatively simple models. FE models can be more detailed and have the advantage of providing stress and strain data for individual tissues. Therefore, they are well suited to study injury mechanics, to find injury tolerances, determine risk functions, and in the design of preventive systems.Recent development of automotive safety systems imposes new requirements on HBM. Systems that can detect and prevent accidents are integrated with systems that become active when the accident is occurring (Aparicio 2005). The occupant's interaction with safety systems in the pre-crash phase will change the injury outcome in the crash phase. Therefore, HBM that are biofidelic in the pre-crash phase and during the crash phase can be used to study how the integrated safety systems change the injury risk during crash scenarios. FE HBM models used today lack two features that are important for simulation of pre-crash scenarios: