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2021
DOI: 10.1016/j.scitotenv.2020.142649
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A comprehensive review on chlorpyrifos toxicity with special reference to endocrine disruption: Evidence of mechanisms, exposures and mitigation strategies

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Cited by 140 publications
(61 citation statements)
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“…damage, embryonic malformations and DNA damage, influence on the mental development in children, immunological disorders and effect on male reproductive system [19,20]. It has also been shown that exposure to CPF can enhance the growth of breast tumors and be a risk factor for developing breast cancer [21].…”
Section: Introductionmentioning
confidence: 99%
“…damage, embryonic malformations and DNA damage, influence on the mental development in children, immunological disorders and effect on male reproductive system [19,20]. It has also been shown that exposure to CPF can enhance the growth of breast tumors and be a risk factor for developing breast cancer [21].…”
Section: Introductionmentioning
confidence: 99%
“…However, CP is relatively persistent in the environment, with a half-life in soil from 60-120 days [8] and is also highly toxic to both terrestrial and aquatic organisms [9] by causing immunotoxic and neurotoxic effects in humans and animals [10,11]. The presence of chlorpyrifos can be detected in agricultural soil and water samples throughout the world, even after it has been banned in most countries [12]. Due to its easy availability, low price and expensive agricultural basis, chlorpyrifos is the most commonly used pesticide in South America and Asian countries such as Pakistan, India, etc.…”
Section: Introductionmentioning
confidence: 99%
“…OP insecticides are grouped as moderately hazardous, class II by WHO. The toxicity of CPF was related to neurological dysfunctions, endocrine disruption, and cardiovascular diseases (CVDs) ( ur Rahman et al, 2021 ). The lethal human doses limit is 90–444 mgkg −1 .…”
Section: Introductionmentioning
confidence: 99%