A comprehensive review on chlorpyrifos toxicity with special reference to endocrine disruption: Evidence of mechanisms, exposures and mitigation strategies
“…damage, embryonic malformations and DNA damage, influence on the mental development in children, immunological disorders and effect on male reproductive system [19,20]. It has also been shown that exposure to CPF can enhance the growth of breast tumors and be a risk factor for developing breast cancer [21].…”
Chlorpyrifos (CPF), an organophosphate insecticide, due to its high efficiency and low cost is widely used in the agricultural industry. CPF may lead to lung deficiency, central nervous system damage, developmental and autoimmune disorders. In recent decades, the advanced oxidation processes (AOPs) have been considered in water and wastewater treatment due to their high efficiency in decomposition of organic and inorganic compounds, specially hardly biodegradable or non-biodegradable compounds. In the present review study, the most common AOPs (such as Fenton and Photo-Fenton processes, UV/H 2 O 2 photolysis, UV/TiO 2 heterogeneous photo catalysis, electrochemical processes, sonolysis technology, gamma irradiation technology and sulfate-based AOPs) applied for CPF removal from aqueous matrices has been investigated. It can be concluded that the use of AOPs are effective for CPF removal from aqueous media. In addition, Fenton and photocatalytic processes appear to be the most common techniques for CPF degradation.
“…damage, embryonic malformations and DNA damage, influence on the mental development in children, immunological disorders and effect on male reproductive system [19,20]. It has also been shown that exposure to CPF can enhance the growth of breast tumors and be a risk factor for developing breast cancer [21].…”
Chlorpyrifos (CPF), an organophosphate insecticide, due to its high efficiency and low cost is widely used in the agricultural industry. CPF may lead to lung deficiency, central nervous system damage, developmental and autoimmune disorders. In recent decades, the advanced oxidation processes (AOPs) have been considered in water and wastewater treatment due to their high efficiency in decomposition of organic and inorganic compounds, specially hardly biodegradable or non-biodegradable compounds. In the present review study, the most common AOPs (such as Fenton and Photo-Fenton processes, UV/H 2 O 2 photolysis, UV/TiO 2 heterogeneous photo catalysis, electrochemical processes, sonolysis technology, gamma irradiation technology and sulfate-based AOPs) applied for CPF removal from aqueous matrices has been investigated. It can be concluded that the use of AOPs are effective for CPF removal from aqueous media. In addition, Fenton and photocatalytic processes appear to be the most common techniques for CPF degradation.
“…However, CP is relatively persistent in the environment, with a half-life in soil from 60-120 days [8] and is also highly toxic to both terrestrial and aquatic organisms [9] by causing immunotoxic and neurotoxic effects in humans and animals [10,11]. The presence of chlorpyrifos can be detected in agricultural soil and water samples throughout the world, even after it has been banned in most countries [12]. Due to its easy availability, low price and expensive agricultural basis, chlorpyrifos is the most commonly used pesticide in South America and Asian countries such as Pakistan, India, etc.…”
The widespread environmental contamination of chlorpyrifos (CP) has raised human health concerns and necessitated cost-effective methods for its remediation. The current study evaluated the degradation behavior of CP in compost and biochar amended and unamended (original and sterilized) soils in an incubation trial. Two levels of CP (100 and 200 mg kg−1), compost and biochar (0.50%) were applied, and soil was collected at different time intervals. At the higher CP level (200 mg kg−1), CP a showed lower degradation rate (ƙ = 0.0102 mg kg−1 d−1) compared with a low CP level (ƙ = 0.0173 mg kg−1 d−1). The half-lives of CP were 40 and 68 days for CP at 100 and 200 mg kg−1 in original soil, respectively, and increased to 94 and 141 days in sterilized soils. CP degradation was accelerated in compost amended soils, while suppressed in biochar amended soils. Lower half lives of 20 and 37 days were observed with compost application at CP 100 and 200 mg kg−1 doses, respectively. The activities of soil enzymes were considerably affected by the CP contamination and significantly recovered in compost and biochar amended soils. In conclusion, the application of organic amendments especially compost is an important strategy for the remediation of CP contaminated soil.
“…OP insecticides are grouped as moderately hazardous, class II by WHO. The toxicity of CPF was related to neurological dysfunctions, endocrine disruption, and cardiovascular diseases (CVDs) ( ur Rahman et al, 2021 ). The lethal human doses limit is 90–444 mgkg −1 .…”
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