A Comprehensive Review of the Structure Elucidation of Tannins from <i>Terminalia</i> Linn.

Zhang, Qiunan; Liang, Wenyi; Zhou, Kun; Jian, Ping; She, Gaimei; Zhang, Lanzhen

doi:10.1155/2019/8623909

Cited by 32 publications

(33 citation statements)

References 183 publications

(57 reference statements)

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“…secondary metabolite profiles of calli were influenced by nutrient, temperature, light, growthregulating substance, and carbon source [26,37,38]. This result is different from the study results of Syamkumar et al [39], which states that the metabolite profiles of callus compounds and leaves are identical.…”

Section: Plos Onecontrasting

confidence: 76%

Growth, secondary metabolite production, and in vitro antiplasmodial activity of Sonchus arvensis L. callus under dolomite [CaMg(CO3)2] treatment

et al. 2021

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Malaria is still a global health problem. Plasmodium is a single-cell protozoan parasite that causes malaria and is transmitted to humans through the female Anopheles mosquito. The previous study showed that Sonchus arvensis L. callus has antiplasmodial activity. Several treatments are needed for callus quality improvement for antimalarial compound production. This study aimed to examine the effect of dolomite [CaMg(CO3)2] on growth (morpho-anatomical structure and biomass), secondary metabolite production, and in vitro antiplasmodial activity of S. arvensis L. callus. In this study, leaf explants were grown in Murashige and Skoog medium with a combination of 2,4-dichlorophenoxyacetic acid (2,4-D, one mg/L) and 6-benzyl amino purine (BAP, 0.5 mg/L) with dolomite (50, 75, 100, 150, and 200 mg/L). The 21 days callus ethanolic and methanolic extract were analyzed by gas chromatography-mass spectrometry (GC-MS) and thin-layer chromatography (TLC). The antiplasmodial test was performed on a blood culture infected with Plasmodium falciparum strain 3D7 using the Rieckmann method. The results showed that dolomite significantly affected callus growth, metabolite profile, and in vitro antiplasmodial activity. Dolomite (150 mg/L) showed the highest biomass (0.590 ± 0.136 g fresh weight and 0.074 ± 0.008 g dry weight). GC-MS analysis detected four compounds from callus ethanolic extract. Pelargonic acid, decanoic acid, and hexadecanoic acid were major compounds. One new terpenoid compound is based on TLC analysis. S. arvensis L. callus has antiplasmodial activity with the IC50 value of 5.037 μg/mL. It was three times lower than leaf methanolic extract and five times lower than leaf ethanolic extract.

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Section: Plos Onecontrasting

confidence: 76%

Growth, secondary metabolite production, and in vitro antiplasmodial activity of Sonchus arvensis L. callus under dolomite [CaMg(CO3)2] treatment

et al. 2021

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“…Over 82 different tannins have been identified from different parts of several Terminalia spp. plants [56].…”

Section: Tanninsmentioning

confidence: 99%

Phenolics from Medicinal and Aromatic Plants: Characterisation and Potential as Biostimulants and Bioprotectants

et al. 2021

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Biostimulants and bioprotectants are derived from natural sources and can enhance crop growth and protect crops from pests and pathogens, respectively. They have attracted much attention in the past few decades and contribute to a more sustainable and eco-friendly agricultural system. Despite not having been explored extensively, plant extracts and their component secondary metabolites, including phenolic compounds have been shown to have biostimulant effects on plants, including enhancement of growth attributes and yield, as well as bioprotectant effects, including antimicrobial, insecticidal, herbicidal and nematicidal effects. Medicinal and aromatic plants are widely distributed all over the world and are abundant sources of phenolic compounds. This paper reviews the characterisation of phenolic compounds and extracts from medicinal and aromatic plants, including a brief overview of their extraction, phytochemical screening and methods of analysis. The second part of the review highlights the potential for use of phenolic compounds and extracts as biostimulants and bioprotectants in agriculture as well as some of the challenges related to their use.biostimulant; bioprotectant; phenolic; medicinal; aromatic

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“…These compounds also have high solubility in methanol and could therefore be in large quantitative in the present sample. T. mollis extract also contain other active compounds including urolithins and benzopyranones, which are cystein protease inhibitors [46][47][48]. The plant has been tested and showed good antioxidant activity attributed to ellagitannins, ellagic acid, as well as condensed tannins such as catechin, epicatechin, gallocatechin and apigallocatechin as well as garlic acid and derivates [49,50].…”

Section: Discussionmentioning

confidence: 99%

In Vitro Antileishmanial Activities of Olea europaea, Kigelia africana, Terminalia mollis, Croton Macrostachyus and Bridella micrantha, Kenyan Medicinal Plants

Wafula

Ayieko

Collins

et al. 2020

IJTDH

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Leishmaniasis is a major public health problem globally. Visceral leishmaniasis is known to be fatal if left untreated, while cutaneous leishmaniasis is the most neglected. The first-line treatment of leishmaniasis is based on pentavalent antimonial drugs which are expensive, requiring inpatient treatment and toxic. The Plants containing active compounds against other protozoan diseases may offer alternatives against leishmania parasites. This study determined the in vitro antileishmanial activity of Olea europaea, Kigelia africana, Terminalia mollis, Croton macrostachyus and Bridella micrantha extracts. The plant samples were dried, pulverized into fine powders and extracted using ethanol at the Center for Traditional Medicine and Drugs Research, KEMRI. The in vitro assays were carried out at the Leishmania laboratory, Centre for Biotechnology Research and Development, KEMRI. In in- vitro assays the inhibitory concentrations (IC50) and Minimum Inhibition Concentration (MIC) on L. major promastigotes, percentage rates of macrophages infected by amastigotes and cytotoxicity on Vero cells were determined. For each parameter analyzed, differences among treatment groups exposed to different drugs were tested by logistic regression. Results showed that promastogote and amastigote growth inhibition was significantly affected by the crude extracts from the plants (P < 0.05) after 24 hours of exposure where the most effective drug was the standard drug (Amphotericin B) while among the crude extracts of the herbal drugs, T. mollis was the most effective against amastigote followed by C. macrostachyus while O. europaea was the least effective. Mammalian cell viability was significantly affected by the various test compounds (P < 0.05) after 24 hours exposure where % cell viability of herbal drugs, B. microstachyus, O. africana resulted to the most toxic effects by reducing the % cell viability to less than 50%. The study recommends the use of T. mollis in management of leishmaniasis in areas they occur. Further analysis of the active compounds that that affect efficacy of the plant extracts is advised.

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A Comprehensive Review of the Structure Elucidation of Tannins from Terminalia Linn.

Cited by 32 publications

References 183 publications

Growth, secondary metabolite production, and in vitro antiplasmodial activity of Sonchus arvensis L. callus under dolomite [CaMg(CO3)2] treatment

Growth, secondary metabolite production, and in vitro antiplasmodial activity of Sonchus arvensis L. callus under dolomite [CaMg(CO3)2] treatment

Phenolics from Medicinal and Aromatic Plants: Characterisation and Potential as Biostimulants and Bioprotectants

In Vitro Antileishmanial Activities of Olea europaea, Kigelia africana, Terminalia mollis, Croton Macrostachyus and Bridella micrantha, Kenyan Medicinal Plants

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