A comparison of experimental compressive axial loading testing with a numerical simulation of topologically optimized cervical implants made by selective laser melting

Schnitzer, Marek; Hudák, Radovan; Sedlačko, Peter; Rajťúková, Viktória; Balogová, Alena Findrik; Živčák, Jozef; Kula, Tomáš; Bocko, Jozef; Džupon, Miroslav; Ižaríková, Gabriela; Karasek, M; Filip, Vladimír; Ivančová, Eleonóra; Sajty, M.; Szedlák, Peter; Somoš, Andrej

doi:10.1016/j.jbiotec.2020.07.010

Cited by 5 publications

(6 citation statements)

References 32 publications

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“…The reason for this is that bone growth occurs in the cage’s microporous structure, resulting in a greater overall mechanical structural stability and more effective fusion ( McGilvray et al, 2018 ). The holes, in addition to providing space for new bone to grow in, can be used for the injection of bioactive structures, such as BMPs, antibiotics, and bioceramics, as well as for post-processing for better fusion results ( Schnitzer et al, 2020 ).…”

Section: Strategies For Designing Interbody Fusion Cagesmentioning

confidence: 99%

Biomaterials for Interbody Fusion in Bone Tissue Engineering

Zhang

Wang

et al. 2022

Front. Bioeng. Biotechnol.

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In recent years, interbody fusion cages have played an important role in interbody fusion surgery for treating diseases like disc protrusion and spondylolisthesis. However, traditional cages cannot achieve satisfactory results due to their unreasonable design, poor material biocompatibility, and induced osteogenesis ability, limiting their application. There are currently 3 ways to improve the fusion effect, as follows. First, the interbody fusion cage is designed to facilitate bone ingrowth through the preliminary design. Second, choose interbody fusion cages made of different materials to meet the variable needs of interbody fusion. Finally, complete post-processing steps, such as coating the designed cage, to achieve a suitable osseointegration microstructure, and add other bioactive materials to achieve the most suitable biological microenvironment of bone tissue and improve the fusion effect. The focus of this review is on the design methods of interbody fusion cages, a comparison of the advantages and disadvantages of various materials, the influence of post-processing techniques and additional materials on interbody fusion, and the prospects for the future development of interbody fusion cages.

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Section: Strategies For Designing Interbody Fusion Cagesmentioning

confidence: 99%

Biomaterials for Interbody Fusion in Bone Tissue Engineering

Zhang

Wang

et al. 2022

Front. Bioeng. Biotechnol.

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“…Titanium-based alloys Ti6Al4V wrought products have been used extensively for implant structures in bone healing and remodeling within the medical sector. With the advent of SLM today, it is possible to print one-of-a-kind tailored implants for subject-specific damaged or resected bone regions (Jamshidi et al, 2020;Munir et al, 2020;Schnitzer et al, 2020). Combinations with other alloy elements that provide better osteogenesis have also been a current subject of intense research.…”

Section: Feedstock Materials Used In the Selective Laser Melting Processmentioning

confidence: 99%

Selective laser melting: lessons from medical devices industry and other applications

Fé-Perdomo

Ramos‐Grez

Beruvides³

et al. 2021

RPJ

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Purpose The purpose of this paper is to outline some key aspects such as material systems used, phenomenological and statistical process modeling, techniques applied to monitor the process and optimization approaches reported. All these need to be taken into account for the ongoing development of the SLM technique, particularly in health care applications. The outcomes from this review allow not only to summarize the main features of the process but also to collect a considerable amount of investigation effort so far achieved by the researcher community. Design/methodology/approach This paper reviews four significant areas of the selective laser melting (SLM) process of metallic systems within the scope of medical devices as follows: established and novel materials used, process modeling, process tracking and quality evaluation, and finally, the attempts for optimizing some process features such as surface roughness, porosity and mechanical properties. All the consulted literature has been highly detailed and discussed to understand the current and existing research gaps. Findings With this review, there is a prevailing need for further investigation on copper alloys, particularly when conformal cooling, antibacterial and antiviral properties are sought after. Moreover, artificial intelligence techniques for modeling and optimizing the SLM process parameters are still at a poor application level in this field. Furthermore, plenty of research work needs to be done to improve the existent online monitoring techniques. Research limitations/implications This review is limited only to the materials, models, monitoring methods, and optimization approaches reported on the SLM process for metallic systems, particularly those found in the health care arena. Practical implications SLM is a widely used metal additive manufacturing process due to the possibility of elaborating complex and customized tridimensional parts or components. It is corroborated that SLM produces minimal amounts of waste and enables optimal designs that allow considerable environmental advantages and promotes sustainability. Social implications The key perspectives about the applications of novel materials in the field of medicine are proposed. Originality/value The investigations about SLM contain an increasing amount of knowledge, motivated by the growing interest of the scientific community in this relatively young manufacturing process. This study can be seen as a compilation of relevant researches and findings in the field of the metal printing process.

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Section: Introductionmentioning

confidence: 99%

“…Schnitzer et al 25 optimized a titanium cage called Ti6A14V using the finite element method. They applied a compressive load of 70 kN on the cage and introduced an optimal cage that minimized the stiffness to reduce subsidence.…”

Section: Introductionmentioning

confidence: 99%

“…In general, cage optimization can be carried out in form of mechanical 23 and design algorithms such as Taguchi 14 and asymptotic homogeneous method 24 or with help of the finite element methods. 25 Moussa et al 23 optimized a toothless lumbar cage using a density-based mechanical algorithm through relatively cumbersome calculations. Their objective function was to minimize the amount of subsidence.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Optimization of cervical cage and analysis of its base material: A finite element study

Jalilvand

Abolfathi

Khajehzadeh

et al. 2022

Proc Inst Mech Eng H

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Nowadays, cervical disorders are common due to human lifestyles. Accordingly, the cage design should be optimized as an essential issue. For an optimal design, an objective function is utilized to calculate the proper geometrical parameters. Additionally, the base material of the cage plays a key role in its functionality and final cost. Novel materials are currently introduced with more compatibility with the bone in terms of mechanical and chemical properties. In this study, a cervical cage was modeled based on PEEK material with three types of tooth designs on its surface. The cervical cage is assumed to be implanted between C6 and C7 vertebrae. The geometric parameters of the cage were optimized to minimize the mass by determining allowable stress and subsidence. The effect of complete cortical removal was investigated as a surgical mistake. Finally, a new composition of PEEK/titanium was introduced as the base material of the cage. Ansys 18.2 was used for FEA. The cage with a straight tooth was chosen due to its lower stress and subsidence compared with other designs. Furthermore, the optimized structures of all three tooth designs were determined. The mass and volume of the optimal cages were reduced by 41.47% and 41.52% respectively. Besides, complete cortical resection should not be carried out during fusion surgery, since it may lead to higher subsidence. The composition of PEEK/titanium was chosen as an appropriate base material due to its better performance compared with PEEK or titanium alone.

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A comparison of experimental compressive axial loading testing with a numerical simulation of topologically optimized cervical implants made by selective laser melting

Cited by 5 publications

References 32 publications

Biomaterials for Interbody Fusion in Bone Tissue Engineering

Biomaterials for Interbody Fusion in Bone Tissue Engineering

Selective laser melting: lessons from medical devices industry and other applications

Optimization of cervical cage and analysis of its base material: A finite element study

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