A Comparative Study on the Antimicrobial Susceptibility Patterns of Klebsiella and Enterobacter Species from the Lagos University Teaching Hospital

Aibinu, I.; Ohaegbulam, V.C.; Odugbemi, T

doi:10.4314/jnica.v3i2.10720

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“…Isolates were susceptible to gentamycin and ceftazidime. This high susceptibility pattern might support gentamycin as a suitable antibiotics to treat Klebsiella infection 22 . Among eight isolated Pseudomonas spp., all were resistant to cephradine, penicillin, cloxacillin, cefuroxime, amoxicillin, and cefotaxime in this study.…”

Section: Discussionmentioning

confidence: 83%

Evaluation of antibiotic susceptibility in wound infections: A pilot study from Bangladesh

Roy¹,

Ahmed²,

Uddin³

et al. 2017

F1000Res

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Introduction: Infections due to antibiotic resistant bacteria have increased alarmingly in both developed and developing countries. Unrestrained and rapidly spreading bacterial growth has turned the management of wound infections into a serious challenge. This study aimed to determine the prevalence of different bacterial pathogens and their antibiotic susceptibility in various types of wound infections. Methods: A cross-sectional study was conducted to collect 105 wound swabs. All isolated bacteria were identified based on colony characteristics, gram stain and standard biochemical tests, and antibiotic susceptibility testing (AST) with the disc diffusion method. Descriptive statistics were used to present the study findings, and all analyses were performed using Stata Version 13. Results: The rate of isolation of bacteria was 92.3%. Staphylococcus aureus was found to be the most frequent isolate (55.7%), followed by Escherichia coli (23.7%), Pseudomonas spp. (8.2%), and Streptococcus pyogenes (7.2%). Gram-positive bacteria were mostly (60%) found sensitive to vancomycin, azithromycin, gentamicin, imipenem, cefixime, and ceftriaxone in this study. Among the Gram-negative bacteria, Escherichia coli (>60%) showed sensitivity to cefixime, azithromycin, cefuroxime, ceftriaxone, cefotaxime, gentamycin, and ceftazidime. Conclusions: The diversity of isolated bacteria and their susceptibility patterns signify a need to implement a proper infection control strategy, which can be achieved by carrying out antibiotic sensitivity tests of the isolates.

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Section: Discussionmentioning

confidence: 83%