A Comparative Evaluation of In-Vitro Antioxidant Activity of Some Commonly Used Spices of Northern India

Singhal, Paavan; Singla, Neha; Sakhare, Dhanashree; Sharma, Anil Kumar

doi:10.2174/2210315506666161123120821

Cited by 10 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some studies suggest that N. sativa oil and extracts have antioxidant properties and can modulate oxidative stress, which could be beneficial for oxidative stress related diseases/disorders. In this sense, oils and solvent extracts from N. sativa seeds possessed antioxidant activity in vitro ( Toma et al, 2015 ; Mohammed et al, 2016 ; Abedi et al, 2017 ; Singhal et al, 2017 ), ex vivo ( Ghoreyshi et al, 2020 ), in vivo ( Mahmoudi et al, 2018 ; Rasoli et al, 2018 ) and in humans ( Nikkhah-Bodaghi et al, 2019 ). Moreover, in vivo regular intake of ethanolic extract of N. sativa seed (400 mg/kg) lowered the lipid peroxidation, and enhanced catalase activity in Wistar rats ( Rasoli et al, 2018 ).…”

Section: Biological Activities: Preclinical In Vitro/in Vivo Studies Of the Genus Nigella And Activmentioning

confidence: 99%

Nigella Plants – Traditional Uses, Bioactive Phytoconstituents, Preclinical and Clinical Studies

et al. 2021

View full text Add to dashboard Cite

Nigella is a small genus of the family Ranunculaceae, which includes some popular species due to their culinary and medicinal properties, especially in Eastern Europe, Middle East, Western, and Central Asia. Therefore, this review covers the traditional uses and phytochemical composition of Nigella and, in particular, Nigella sativa. The pharmacological studies reported in vitro, in vivo, and in humans have also been reviewed. One of the main strength of the use of Nigella is that the seeds are rich in the omega-6 fatty acid linoleic acid and provide an extra-source of dietary phytochemicals, including the bioactive thymoquinone, and characteristics saponins, alkaloids, and flavonoids. Among Nigella species, N. sativa L. is the most studied plant from the genus. Due to the phytochemical composition and pharmacological properties, the seed and seed oil from this plant can be considered as good candidates to formulate functional ingredients on the basis of folklore and scientific knowledge. Nonetheless, the main limations are that more studies, especially, clinical trials are required to standardize the results, e.g. to establish active molecules, dosage, chemical profile, long-term effects and impact of cooking/incorporation into foods.

show abstract

Section: Biological Activities: Preclinical In Vitro/in Vivo Studies Of the Genus Nigella And Activmentioning

confidence: 99%

Nigella Plants – Traditional Uses, Bioactive Phytoconstituents, Preclinical and Clinical Studies

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Spices and herbs have been extensively studied in different countries because of the high antioxidant activity in certain spices and their beneficial effects on human health [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. As part of our diet, spices and herbs, in addition to fruits and vegetables, could provide us with additional sources of natural antioxidants.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activity of Spices and Their Impact on Human Health: A Review

et al. 2017

View full text Add to dashboard Cite

Antioxidants are substances that prevent oxidation of other compounds or neutralize free radicals. Spices and herbs are rich sources of antioxidants. They have been used in food and beverages to enhance flavor, aroma and color. Due to their excellent antioxidant activity, spices and herbs have also been used to treat some diseases. In this review article, the chemical composition and antioxidant activity of spices and culinary herbs are presented. The content of flavonoids and total polyphenols in different spices and herbs are summarized. The applications of spices and their impacts on human health are briefly described. The extraction and analytical methods for determination of antioxidant capacity are concisely reviewed.

show abstract

“…They were housed in netted cages, fed with standard rat's diet and allowed water ad libitum throughout the period of the study. 23,24 The untreated Group received normal saline to expose them to the same stress as other groups. Groups B and C received Lead acetate solution (3.5 mg/kg) daily and 24 -hours later the aqueous extract was administered.…”

Section: Experimental Design and Groupingmentioning

confidence: 99%

Ficus vogelii Stembarks; A Promising Herbal Remedy for Lead Induced Reproductive Toxicity

Obinna¹,

Egwu²,

Uzomba³

et al. 2020

BIOMEDICA

View full text Add to dashboard Cite

Background and Objectives:Toxicity is fast becoming a major cause of infertility in this century unknowingly and researchers can no longer be mute over this situation. In this work, we aimed at exploring the potency of the bark of Ficus vogelii as an herbal product in protecting against female toxicity. Methods:The twenty 25 female Wistar rats used weighed between 140 -180g and were randomly assigned into five groups of five rats per group with group A servicing as control which received normal saline. Groups B and C received 3.5 mg/kg of Lead acetate 14 days and later received low and high dose of extract respectively. Group D served as lead acetate group while group E received extract only.Results: There were changes in body, uterine and ovarian weight (P > 0.01). Superoxide Dismutase (SOD) enzyme levels were reduced significantly in B and C (P > 0.01) group animals while there was an increase in its levels in group D. Several alterations were seen in the ovary and uterus which includes reduced folliculogenesis with a marked increase in the number of atretic follicles, oedema and necrotic zones. These effects were seen to be restored near normal in the groups that were administered with extract. Conclusions:This work showed that the bark of Ficus vogelii could be a good herbal remedy for infertility.

show abstract

A Comparative Evaluation of In-Vitro Antioxidant Activity of Some Commonly Used Spices of Northern India

Cited by 10 publications

References 0 publications

Nigella Plants – Traditional Uses, Bioactive Phytoconstituents, Preclinical and Clinical Studies

Nigella Plants – Traditional Uses, Bioactive Phytoconstituents, Preclinical and Clinical Studies

Antioxidant Activity of Spices and Their Impact on Human Health: A Review

Ficus vogelii Stembarks; A Promising Herbal Remedy for Lead Induced Reproductive Toxicity

Contact Info

Product

Resources

About