A Case Report of Prurigo Nodularis-Like Lesions in a Patient with Lepromatous Leprosy

Abstract

Leprosy or Hansen’s disease is a chronic granulomatous infection that primarily affects the peripheral nerves and, consequently, the skin. Clinical manifestations vary from hypopigmentation to erythematous plaques, and it can present with leonine facies. We report a case of a patient with an uncommon clinical presentation of prurigo nodularis-like lesions without loss of sensation, for which two biopsy specimens demonstrated different histological subtypes. The first was the classic histology of lepromatous leprosy, whereas the other specimen revealed an atypical histoid leprosy variant pattern. This case report describes a patient with an atypical presentation of leprosy.

Lepromatous leprosy with a suspected 30-year incubation period: A case report of a practically eradicated area

“…The global prevalence rate of leprosy is 0.2 cases per 10,000 population as of 2018, 3 while its prevalence rate in Thailand is 10-fold lower than the global prevalence in the year 2019 (0.02 cases per 10,000 persons). 4 In Thailand, leprosy as a public health problem is eliminated according to the definition of the World Health Organization (WHO). 3 In 2021, 5 the WHO launched the campaign for “Toward zero leprosy” for the decade.…”