A Case of Hilar Bile Duct Cancer with Intestinal Behcet's Disease

Abstract

We encountered a hilar bile duct cancer patient with intestinal Behçet's disease who manifested various symptoms during a short period in the acute stage after liver resection. Under a diagnosis of hilar bile duct cancer, a 52-year-old Japanese male was referred and admitted to our hospital. Hepatectomy and resection of the extrahepatic bile duct were performed. During the postoperative course, a large number of painful aphthous ulcers developed in the oral mucosa, along with a genital ulcer. A deep excavation-type ulcer was confirmed by colonoscopy in the ileum on the orifice side. We administered colchicine and mesalazine. Thereafter, the patient was treated at the outpatient clinic. Recurrent localized hilar bile duct cancer developed, and the patient died about 8 months after surgery. We present the clinical details of this rare case of hilar bile duct cancer with intestinal Behçet's disease.

Long-term outcome after surgery in a patient with intestinal Behçet’s disease complicated by myelodysplastic syndrome and trisomy 8

“…In conclusion, we report the first case in which surgery provided a favorable 5-year outcome in a patient with MDS-associated BD. As shown in Table 2, 9,10,[15][16][17][18][19][20] there is no case that surgery provides a long-term outcome like our case. The diagnosis and treatment of such patients may be complicated, but we believe that an improved understanding of this complex disease and collaborative therapy can lead to improved care and reduce adverse outcomes.…”

Behcet's disease associated with malignancy: a report of 41 Chinese cases

“…Based on the reports and literature review by Kaklamani, 3 we performed a Medline search from 2004 through 2012 which yielded a total of 167 BD cases with malignancies. 3,4,[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] Malignancies were diagnosed after BD in 132 cases, coincidentally with BD in eight cases and before BD in 27 cases (Table 4). However, several studies demonstrated that the age-standardized rate of cancer in the population of BD patients did not differ significantly from that of the corresponding general population.…”

“…Summaryof BD patients with various types of malignancies from PUMCH and in the literature3,4,[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] …”