A case of angioedema-like atypic scleromyxedema responding to treatment with steroid

Polat, Aysegul Yucel; Kapıcıoğlu, Yelda; Şahin, Nurhan; Yılmaz, Mikail

doi:10.4274/turkderm.04809

Cited by 3 publications

(6 citation statements)

References 13 publications

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“…47 It is marked by abrupt onset, permanent, asymptomatic, bilateral edema. 48 Thin, rough, hyperkeratotic skin is another common dermatological manifestation of hypothyroidism. 47 The diagnosis is confirmed by low levels of thyroid hormone and treatment is with hormone replacement therapy.…”

Section: Mucinosis and Other Infiltrating Diseasesmentioning

confidence: 99%

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If not angioedema, what is it? Diagnostic approach to facial edema

Velasco‐Amador,

Prados‐Carmona,

Navarro‐Triviño

2024

J Deutsche Derma Gesell

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SummaryFacial edema is a relatively frequent clinical presentation encountered in patients seen in allergology and dermatology clinics. The differential diagnosis is broad, and sometimes the definitive diagnosis can be a challenge for the clinician. Facial angioedema itself encompasses different etiopathologies (histaminergic, bradykinergic, etc.) that must be distinguished from other causes of facial edema, such as allergic contact dermatitis, granulomatous conditions, inflammatory causes, infections, neoplasms or paraneoplastic syndromes, autoimmune diseases, among other entities hereby referred as miscellanea. A proper diagnostic approach is essential to order the appropriate tests, as well as to prescribe a targeted treatment. This review focuses on entities that present with facial edema and summarize their characteristic clinical features.

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Section: Mucinosis and Other Infiltrating Diseasesmentioning

confidence: 99%

“…Severe hypothyroidism can present with facial, particularly palpebral, edema, which is very similar to angioedema but is not as transient as angioedema 47 . It is marked by abrupt onset, permanent, asymptomatic, bilateral edema 48 . Thin, rough, hyperkeratotic skin is another common dermatological manifestation of hypothyroidism 47 .…”

Section: Miscellaneousmentioning

confidence: 99%

If not angioedema, what is it? Diagnostic approach to facial edema

Velasco‐Amador,

Prados‐Carmona,

Navarro‐Triviño

2024

J Deutsche Derma Gesell

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“…47 Es zeichnet sich durch ein plötzlich einsetzendes, dauerhaftes, asymptomatisches, bilaterales Ödem aus. 48 Dünne, raue, hyperkeratotische Haut ist eine weitere häufige dermatologische Manifestation der Hypothyreose. 47 Die Diagnose wird durch niedrige Schilddrüsenhormonwerte bestätigt, und die Therapie erfolgt mit einer Hormonersatztherapie.…”

Section: Muzinose Und Andere Infiltrierende Krankheitenunclassified

Wenn es kein Angioödem ist, was dann? Diagnostisches Vorgehen bei Gesichtsödemen

Velasco‐Amador,

Prados‐Carmona,

Navarro‐Triviño

2024

J Deutsche Derma Gesell

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ZusammenfassungGesichtsödeme sind ein relativ häufiges Symptom bei Patienten allergologischer und dermatologischer Kliniken. Die Differentialdiagnose ist breit gefächert und die endgültige Diagnose kann manchmal eine Herausforderung für den Kliniker sein. Das faziale Angioödem selbst umfasst verschiedene Ätiopathologien (histaminerg, bradykinininduziert und weitere), die von anderen Ursachen des Gesichtsödems differenziert werden sollten, etwa allergischer Kontaktdermatitis, granulomatösen Erkrankungen, inflammatorischen Ursachen, Infektionen, Neoplasmen oder paraneoplastischen Syndromen, Autoimmunerkrankungen und anderen Entitäten, die hier als „Sonstige“ bezeichnet werden. Um die richtigen Untersuchungen anzuordnen und eine gezielte Therapie zu verordnen, ist ein angemessener diagnostischer Ansatz ausschlaggebend. Diese Übersicht konzentriert sich auf Entitäten, die mit Gesichtsödem einhergehen, und fasst ihre klinischen Charakteristika zusammen.

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“…It is frequently detected with paraproteinemia [1,2,49,50]. The clinical features consist of forehead swelling and deep longitudinal furrows cause a lion-like face [49,50].…”

Section: Mucinosis and Other Infiltrating Disordersmentioning

confidence: 99%

“…The clinical features consist of forehead swelling and deep longitudinal furrows cause a lion-like face [49,50].…”

Section: Mucinosis and Other Infiltrating Disordersmentioning

confidence: 99%

Pseudoangioedema

Akarsu¹,

Canturk²

2017

A Comprehensive Review of Urticaria and Angioedema

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Angioedema is a rapid, localized and temporary subcutaneous edema, which targets the lips, eyelids, gastrointestinal and respiratory mucosa resulting in abdominal pain, asthma and even serious life-threatening conditions like airway obstruction. There are several other disorders such as allergic contact dermatitis, drug rash with eosinophilia and systemic symptoms (DRESS), superior vena cava syndrome (SVCS), orofacial granulomatosis and so on, which manifest with subcutaneous swelling and masquerade as angioedema and are known as 'pseudoangioedema' in the literature. Knowledge of pseudoangioedema for healthcare professionals is crucial to avoid potentially serious results of misdiagnosis such as further investigations, unnecessary applications and delayed diagnosis. We aim to discuss differential diagnosis of angioedema and help physicians recognize the typical features of angioedema and its differential diagnosis in this chapter.

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A case of angioedema-like atypic scleromyxedema responding to treatment with steroid

Cited by 3 publications

References 13 publications

If not angioedema, what is it? Diagnostic approach to facial edema

If not angioedema, what is it? Diagnostic approach to facial edema

Wenn es kein Angioödem ist, was dann? Diagnostisches Vorgehen bei Gesichtsödemen

Pseudoangioedema

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