A Bioactive Glass Particulate in the Treatment of Molar Furcation Invasions

Anderegg, Charles R.; Alexander, David C.; Freidman, M.

doi:10.1902/jop.1999.70.4.384

Cited by 59 publications

(63 citation statements)

References 10 publications

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“…In this study, the size of the S-TCP(G) particles was 300-500 µm. In previous studies 24,25) , β-TCP with a pore size of 300-500 µm facilitated bone remodeling, with a good vascular network and relatively uninhibited bone ingrowth. Therefore, S-TCP(G) particles of 300-500 µm in diameter are presently used as a scaffold for PDGF-BB.…”

Section: Discussionmentioning

confidence: 90%

Effect of β tricalcium phosphate particle size on recombinant human platelet-derived growth factor-BB-induced regeneration of periodontal tissue in dog

Irokawa¹,

Ota²,

Yamamoto³

et al. 2010

Dent. Mater. J.

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The aim of this study was to investigate the effect of β tricalcium phosphate (β-TCP) particle size on recombinant human plateletderived growth factor-BB (rhPDGF-BB)-induced regeneration of periodontal tissue in dog. The control group (rhPDGF-BB alone) was characterized by incomplete, newly formed bone. The large-particle β-TCP (L-TCP(O))/rhPDGF-BB group showed a statistically significant increase in both new bone and cementum formation compared to the small-particle β-TCP (S-TCP(G))/rhPDGF-BB group. These findings suggest that L-TCP(O)-particle promotes rhPDGF-BB-induced formation of bone and cementum.

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Section: Discussionmentioning

confidence: 90%

Effect of β tricalcium phosphate particle size on recombinant human platelet-derived growth factor-BB-induced regeneration of periodontal tissue in dog

Irokawa¹,

Ota²,

Yamamoto³

et al. 2010

Dent. Mater. J.

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“…The high fill density of granule biomaterials indicated good bone formation 14) . The 300-500 μm of the particle diameter allowed efficient migration of bone-producing cells and colonization by blood vessels, that are essential for new bone formation 15,16) . Therefore, we used IP-CHA granules of approximately 500 μm diameter as a graft material.…”

Section: Discussionmentioning

confidence: 99%

Inorganic polyphosphate adsorbed onto hydroxyapatite for guided bone regeneration: An animal study

et al. 2014

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Inorganic polyphosphate (poly(P)) is recognized as a therapeutic agent that promotes fibroblast growth factor and enhances osteogenic differentiation, and in vivo, when adsorbed onto interconnected porous calcium hydroxyapatite (IP-CHA) enhances bone regeneration. The present study focused on the effect of poly(P) adsorbed onto IP-CHA granules (Poly(P)/IP-CHA) in guided bone regeneration (GBR). Dental implants were placed into the edentulous mandibular areas of five Beagle-Labrador hybrid dogs with screw expose on the buccal side, and then bone defects were filled Poly(P)/IP-CHA (test) or IP-CHA (control). After 12 weeks, histological evaluation and histomorphometrical analysis were performed. Newly-bone formation around exposed implant screw was clearly detected in the test-group. The ratio for regenerated bone height in the test group versus the control-group was 85.6±20.2 and 62.6±23.8, respectively, with no significant difference, while, that for bone implant contact was significantly higher (67.9±11.8 and 48.8±14.1, respectively). These findings indicate that Poly(P)/IP-CHA enhances bone regeneration in GBR.

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“…Perioglas® though act as an osteoconductive scaffold but also interacts with the surrounding tissues and imparts an osteostimulatory effect. This phenomenon achieves faster bone regeneration than exhibited by osteoconduction, while simultaneously increasing the resorption rate of the implanted graft material (11) .…”

Section: Materials Usedmentioning

confidence: 99%

“…Researchers suggest hat bioactive glass is a potential bone replacement graft material. Thus it is an effective adjunct to conventional surgery in the treatment of periodontal infrabony defects (11) . Hence the present clinical study was aimed to evaluate the clinical and radiographic outcomes of PRF and Perioglas® in infrabony defects of chronic generalized periodontitis patients.…”

Section: Perioglas ® and Prf As Graft Materials In The Treatment Of Imentioning

confidence: 99%

Perioglas® And Prf As Graft Materials in The Treatment of Intrabony Defects in Chronic Generalized Periodontitis: A Clinical And Radiological Evaluation

Singh¹,

Chandrashekar²,

Mishra³

et al. 2016

IOSR

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A Bioactive Glass Particulate in the Treatment of Molar Furcation Invasions

Abstract: This study revealed the benefits of bioactive glass in the treatment of Class II furcation defects regarding the clinical parameters of probing depth reduction and the reduction in bleeding on probing.

Cited by 59 publications

References 10 publications

Effect of β tricalcium phosphate particle size on recombinant human platelet-derived growth factor-BB-induced regeneration of periodontal tissue in dog

Effect of β tricalcium phosphate particle size on recombinant human platelet-derived growth factor-BB-induced regeneration of periodontal tissue in dog

Inorganic polyphosphate adsorbed onto hydroxyapatite for guided bone regeneration: An animal study

Perioglas® And Prf As Graft Materials in The Treatment of Intrabony Defects in Chronic Generalized Periodontitis: A Clinical And Radiological Evaluation

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