Untitled

Muturi, Ephantus J.; Mbogo, Charles M.; Mwangangi, Joseph; Ng’ang’a, Zipporah; Kabiru, Ephantus W.; Mwandawiro, Charles; Beier, John C.

doi:10.1186/1475-2883-5-8

Cited by 41 publications

(24 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…and An.funestus , and they occur year-round with peaks of population abundance coinciding with seasonal rains (Mbogo et al 2003, Mutuku et al 2011). The same mosquitoes transmit LF with an added role for Culex quinquefasciatus (Say) (Diptera: Culicidae) (Bögh et al 1998; Muturi et al 2006a,b). The current estimated population for Msambweni and Kwale districts is 288,000 and 152,000, respectively, totaling ≈440,000 (Kenya National Central Bureau of Statistics 2009).…”

Section: Methodsmentioning

confidence: 99%

Monitoring Malaria Vector Control Interventions: Effectiveness of Five Different Adult Mosquito Sampling Methods

et al. 2013

View full text Add to dashboard Cite

Long-term success of ongoing malaria control efforts based on mosquito bed nets (long-lasting insecticidal net) and indoor residual spraying is dependent on continuous monitoring of mosquito vectors, and thus on effective mosquito sampling tools. The objective of our study was to identify the most efficient mosquito sampling tool(s) for routine vector surveillance for malaria and lymphatic filariasis transmission in coastal Kenya. We evaluated relative efficacy of five collection methods—light traps associated with a person sleeping under a net, pyrethrum spray catches, Prokopack aspirator, clay pots, and urine-baited traps—in four villages representing three ecological settings along the south coast of Kenya. Of the five methods, light traps were the most efficient for collecting female Anopheles gambiae s.l. (Giles) (Diptera: Culicidae) and Anopheles funestus (Giles) (Diptera: Culicidae) mosquitoes, whereas the Prokopack aspirator was most efficient in collecting Culex quinquefasciatus (Say) (Diptera: Culicidae) and other culicines. With the low vector densities here, and across much of sub-Saharan Africa, wherever malaria interventions, long-lasting insecticidal nets, and/or indoor residual spraying are in place, the use of a single mosquito collection method will not be sufficient to achieve a representative sample of mosquito population structure. Light traps will remain a relevant tool for host-seeking mosquitoes, especially in the absence of human landing catches. For a fair representation of the indoor mosquito population, light traps will have to be supplemented with aspirator use, which has potential for routine monitoring of indoor resting mosquitoes, and can substitute the more labor-intensive and intrusive pyrethrum spray catches. There are still no sufficiently efficient mosquito collection methods for sampling outdoor mosquitoes, particularly those that are bloodfed.

show abstract

Section: Methodsmentioning

confidence: 99%

Monitoring Malaria Vector Control Interventions: Effectiveness of Five Different Adult Mosquito Sampling Methods

et al. 2013

View full text Add to dashboard Cite

show abstract

“…The co-occurrence of malarial and filarial parasites has been reported in endemic areas [25-28]. Unlike malaria, filariasis, a neglected disease, is rarely fatal but severe morbidity, including disabilities and adverse economic consequences due to disfigurement of limbs and male genitals (elephantiasis and hydrocele, respectively), occurs in 40% of infected individuals [29,30].…”

Section: Introductionmentioning

confidence: 99%

Diversity of Anopheles mosquitoes in Binh Phuoc and Dak Nong Provinces of Vietnam and their relation to disease

et al. 2014

View full text Add to dashboard Cite

BackgroundHuman malaria is still a burden in Dak Nong and Binh Phuoc Provinces in south-central Vietnam that border Cambodia. Several Anopheles species that transmit human malarial Plasmodium may also transmit Wuchereria bancrofti, the nematode that causes Bancroftian lymphatic filariasis. The objective of this study was to investigate the role of Anopheles species in the transmission of these two pathogens in the two highly malaria endemic provinces of Vietnam.MethodsAnopheles mosquitoes were collected in Dak Nong and Binh Phuoc Provinces in November and December of 2010 and 2011. Human landing catches, paired collections on human and buffalo, and resting captures were made with mouth aspirators. Collections were also made with light traps. Morphological and PCR-based methods were used to identify the species. Real-time PCR was used to detect Plasmodium species and W. bancrofti in individual mosquitoes.ResultsTwenty-four Anopheles species were identified among 797 captured mosquitoes. Anopheles dirus was found in both provinces and was the predominant species in Binh Phuoc Province; An. maculatus was the most prevalent species in Dak Nong Province. Anopheles minimus was collected only in Binh Phuoc Province. Some specimens of An. minimus and An. pampanai were misidentified based on morphology. Four specimens of An. scanloni were identified, and this is the first report of this species of the Dirus Complex in Vietnam. Two females, one An. dirus and one An. pampanai, collected in Binh Phuoc Province were infected with P. vivax, for an overall infection rate of 0.41% (2/486): 0.28% for An. dirus (1/361) and 20% for An. pampanai (1/5). No mosquitoes were found to be infected with P. falciparum, P. knowlesi or W. bancrofti in either province.ConclusionA diversity of Anopheles species occurs in Dak Nong and Binh Phuoc Provinces of Vietnam, several of which are considered to be actual and potential vectors of malarial protozoa and microfilariae. It is highly likely that two of the species, An. dirus and An. pampanai, are active in malaria transmission based on the detection of P. vivax in females of these species. This is the first report of An. scanloni in Vietnam.

show abstract

“…A meta-analysis of 54 experiments conducted on laboratory mice investigating the effects of helminth infection on microparasite density suggested that the effect of interactions is dependent on the species pair [11], although none of the studies considered Wuchereria bancrofti (LF) and Plasmodium (malaria) co-infection. However, it is thought that infection with W. bancrofti increases mosquito susceptibility to Plasmodium infection, since migration of microfilariae disrupts the midgut, allowing Plasmodium easier access through the midgut to the salivary glands [3], [5], [29], [30]. On the other hand, mosquitoes carrying worm parasites have been found to reduce Plasmodium infectivity, with such vectors possessing a lower infection intensity compared to uninfected mosquitoes [31].…”

Section: Introductionmentioning

confidence: 99%

Modelling Co-Infection with Malaria and Lymphatic Filariasis

et al. 2013

View full text Add to dashboard Cite

Malaria and lymphatic filariasis (LF) continue to cause a considerable public health burden globally and are co-endemic in many regions of sub-Saharan Africa. These infections are transmitted by the same mosquito species which raises important questions about optimal vector control strategies in co-endemic regions, as well as the effect of the presence of each infection on endemicity of the other; there is currently little consensus on the latter. The need for comprehensive modelling studies to address such questions is therefore significant, yet very few have been undertaken to date despite the recognised explanatory power of reliable dynamic mathematical models. Here, we develop a malaria-LF co-infection modelling framework that accounts for two key interactions between these infections, namely the increase in vector mortality as LF mosquito prevalence increases and the antagonistic Th1/Th2 immune response that occurs in co-infected hosts. We consider the crucial interplay between these interactions on the resulting endemic prevalence when introducing each infection in regions where the other is already endemic (e.g. due to regional environmental change), and the associated timescale for such changes, as well as effects on the basic reproduction number R0 of each disease. We also highlight potential perverse effects of vector controls on human infection prevalence in co-endemic regions, noting that understanding such effects is critical in designing optimal integrated control programmes. Hence, as well as highlighting where better data are required to more reliably address such questions, we provide an important framework that will form the basis of future scenario analysis tools used to plan and inform policy decisions on intervention measures in different transmission settings.

show abstract

Untitled

Cited by 41 publications

References 26 publications

Monitoring Malaria Vector Control Interventions: Effectiveness of Five Different Adult Mosquito Sampling Methods

Monitoring Malaria Vector Control Interventions: Effectiveness of Five Different Adult Mosquito Sampling Methods

Diversity of Anopheles mosquitoes in Binh Phuoc and Dak Nong Provinces of Vietnam and their relation to disease

Modelling Co-Infection with Malaria and Lymphatic Filariasis

Contact Info

Product

Resources

About